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    The Effect of Smoking on the Carriage of Potential Pathogens in Nasopharynx
    (Erciyes Univ Sch Medicine, 2010) Yetkin, Gulay; Ay, Selma; Yetkin, Ozkan; Tastekin, Nese; Gucluer, Nilay
    Purpose: Smoking is associated with an increased risk of respiratory tract infections in adults and also with oral colonization by some potentially pathogenic microorganisms. Smoking or passive exposure is enhancing bacterial adherence of pathogenic bacteria to the epithelial cells of the oropharingeal mucous membrane. The aim of this study is to determine the effect of active smoking on colonization of potential aerobic pathogens and in the nasopharynx. We evaluated Haemophilus Influenza, Moraxella catarrhalis, Streptococcus pneumoniae, Streptococcus pyogenes, Neisseria meningitidis, Staphylococcus aureus and Candida albicans strains. Material and Methods: Study population; 77 healty hospital personel has been selected from several services. Cultures were obtained using sterile swabs. Specimens collected from the nasopharynx through the mouth. Smokers were classified three groups as: mild smokers (n: 29; 0-10 package/year), moderate (n: 16; 11-20 package/year) and heavy (n: 12; 25+ package/year). Cultures were evaluated with semiquantitative technics (roll plate) Results: We isolated Staphylococcus aureus from 3 specimens, Neisseria meningitidis 1, Acinetobacter 'waif/ 1, E.coll 1, intense Candida alb/cans from 12 specimens, afew mold (Candida albicans ye Candida spp.) from 8 specimens, Haemophilus aphrophilus 1 and Group A If haemolytic streptococcus from 1 specimen. We have isolated pathogenic bacteria from 24 of 57 (8.42) smokers and 4 of 20 (8.20) nonsmokers (p<0.05). Conclusion: Distribution of pathojens in three groups described in smokers as follows; mild smokers (6 pathogcn/29 person) (6 pathogen) (/020), moderate (8 pathogen/16 person) (8 pathogen) (%50), and heavy smokers (10 pathogen/12 person) (10 pathogen) (8.83) (p<0.05). All growth rates within these groups have reisen up in comparison with nonsmokers.