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Öğe A comparison of crystal phenol treatment, midline primary closure and Limberg flap reconstruction methods in female patients with primary pilonidal sinus disease(Edizioni Luigi Pozzi, 2021) Kanlioz, Murat; Uyanikoglu, Hacer; Ekici, Ugur; Karatas, Turgay; Tatli, FaikPilonidal sinus disease (PSD) is a chronic problem often occurs in healthy hirsute men, however, women may also be affected. A range of conservative techniques to surgical flaps have been used to treat this condition. Currently, midline primary closure (MPC) is considered the standard of therapy; however, no statistically significant difference has been noted between primary versus secondary (Karydakis flap or Limberg flap) closure. Recently, flap reconstruction methods have been applied and superiority of these methods have been shown. Treatment methods should be employed to the individual, taking into account recurrence and complication rates of the method, recovery time, patients' preference and surgeon's skill.Öğe THE EFFECTS OF ANTIVIRAL DRUGS ON REGENERATION IN CIRRHOTIC LIVERS: A STUDY OF STATS, INTERLEUKINS AND KI-67(John Wiley & Sons Inc, 2009) Kirimlioglu, Hale; Dirican, Abuzer; Tatli, Faik; Aydin, Burcu; Yilmaz, Sezai; Kirimlioglu, Vedat[Abstract Not Available]Öğe Effects of thymoquinone and curcumin on the regeneration of rat livers subject to 70% hepatectomy(Acta Cirurgica Brasileira, 2018) Gozeneli, Orhan; Tatli, Faik; Gunes, Ali Erdal; Guldur, Muhammed Emin; Taskin, Abdullah; Bardakci, Osman; Yilmaz, MehmetPurpose: To investigate thymoquinone, curcumin and a combination of these two drugs were effective or not at the growth of liver. Methods: Forty female Wistar-Albino rats distributed into five groups of eight rats each, control, thymoquinone, curcumin, and thymoquinone/curcumin groups. Pathological specimens were studied using the Ki-67 Proliferation Index(PI); and arginase(Arg), tissue plasminogen activator(tPA), ceruloplasmin(Cer) and nitric oxide(NO) were studied in biochemical analysis. Results: Our results showed that Ki-67 proliferation index was low in Groups 1. The proliferation coefficient was significantly higher in the Group 2 and Group 4 than in the Group 1 and Group 3.(P < 0.001 between Groups 1 and 2, 1 and 4, and 3 and 4). There was no difference between Groups 2 and 4 (P = 1). The results of the biochemical Arg, tPA and Cer test showed statistically between the Group 1 and Group 2. NO showed significant differences Group 1 and 3. Conclusions: Thymoquinone and curcumin both have known positive effects on the organism. Histological and biochemical tests showed that thymoquinone is more effective than curcumin.Öğe Efficacy of Intragastric Balloon Placement and Botulinum Toxin Injection in Bariatric Endoscopy(Lippincott Williams & Wilkins, 2020) Kanlioz, Murat; Ekici, Ugur; Tatli, Faik; Karatas, TurgayBackground: To evaluate the results obtained from the combination of intragastric botulinum toxin A (IGBTA), intragastric balloon (IGB), and IGBTA(+)IGB in the treatment of obesity. Materials and Methods: Three separate treatment groups were set up. IGBTA, IGB, and IGBTA(+)IGB were administered to Group 1, 2, and 3, respectively. The body mass indexes (BMI) of patients were measured before and 6 months after the treatment. The intragroup and intergroup treatment results have been evaluated. PResults: The mean BMI decreased by 1.6 kg/m(2) in 40 patients who received IGBTA in group 1 (P<0.001), 3.95 kg/m(2) in 42 patients who received IGB in group 2 (P<0.001), and 4.9 kg/m(2) in 39 patients who received IGBTA and IGB in group 3 (P<0.001) after 6 months of treatment. The intolerance because of the application was the highest in group 3, followed by group 2. Conclusion: The treatment was most successful in group 3 followed by group 2 and group 1, respectively. The authors recommend the group 3 treatment, provided that nausea, vomiting, and flatulence have a high index of probability in such a treatment. However, when deciding between group 1 and group 2 treatments, the authors recommend opting for group 2 treatment that shows to be more efficient.Öğe Is the appendix length/diameter ratio an early-indicator for the perforation in acute appendicitis?(2018) Ekici, Uğur; Tatli, Faik; Kanlioz, MuratAim: Acute appendicitis is the most frequent reason for the stomachaches resulting in the surgery. The acute appendicitis perforation might create complications that are of vital importance. In this study, it is aimed to examine the relationship of appendix length/ diameter ratio with acute appendicitis perforation. Material and Methods: Using the pathology results of appendectomy materials of 144 patients that applied to emergency service between March 2013 and May 2014 and were operated due to the suspicion of acute appendicitis, the length/diameter ratios were calculated. The patients were divided into 2 groups as perforated appendicitis and non-perforated appendicitis. The number of patients and the length/diameter ratios were calculated and recorded for both groups. Pearson’s Chi-Square test was used for statistical analysis. Results: In pathological examination of 144 patients involved in this study, non-complicated acute appendicitis was diagnosed in 123 (85.4%) patients, while 21(14.6%) patients were found to have perforation. In present study, the results indicating that the length/ diameter ratio might be used as early indicator for the perforation were achieved. When the appendix length/diameter ratio declined below 10, then the perforation frequency significantly increased (p<0.01). Conclusion: Knowing these rate can help the surgeon in early surgical intervention, so the possible complications of perforated appendicitis might be decreased via early surgical intervention.Öğe Laparoscopic splenectomy with a vessel sealing device(Taylor & Francis As, 2008) Aydin, Cemalettin; Kayaalp, Cuneyt; Olmez, Aydemir; Tatli, Faik; Kirimlioglu, VedatWhen compared with open splenectomy, laparoscopic splenectomy was associated with fewer complications, however, with more hemorrhagic complications. Furthermore, the mean operative time for laparoscopy was significantly longer than for the open procedure. Vessel sealing systems are represented as decreasing operative time and blood loss in Several surgical procedures. The aim of this study is to evaluate the blood loss and operating time of laparoscopic splenectomy with a vessel sealing system. We evaluated 19 laparoscopic splenectomies with a vessel sealing device, particularly focusing on operative blood loss and operating time. Patients were operated in the right lateral decubitus position usually with three ports. In all cases, dissection of the spleen and sealing of hilar vessels and short gastric vessels were performed with a vessel sealing system. No clips, sutures, or monopolar bipolar diathermy were used. Mean operative blood loss was 88ml (range 20400 ml) and mean operative time was 107 minutes (range 45-230 minutes). Both results were better than those of most series of laparoscopic splenectomy performed with endostaplers or endoclips. Laparoscopic splenectomy with a vessel sealing system is safe for all vascular controls in laparoscopic splenectomy and can lead to less blood loss. This technique removes the disadvantage of longer operating times for laparoscopic as compared to open splenectomy.Öğe A new seton tightening method for anal fistula treatment: sailor's knot(Edizioni Luigi Pozzi, 2021) Tatli, Faik; Bardakci, Osman; Ozgonul, Abdullah; Erkmen, Firat; Karaca, Emre; Erol, Mehmet Kenan; Yilmaz, MehmetAIM: There are certain problems experienced while retightening the seton material during the patient follow-ups, such as pain and anaesthesia requirements in perianal fistula. The aim of the present study was to compare a sailor's knot with other seton tightening methods for the surgical treatment of perianal fistulas. MATERIAL AND METHODS: The records of 105 patients who underwent surgeries for perianal fistulas using the seton method between 2016 and 2019 were analysed retrospectively. The demographic characteristics, complaints, fistula localizations, surgery types, hospital stay lengths, postoperative complications and imaging modalities of the patients included in the study were recorded. The patients were divided into two groups according to the surgical treatment method. Those patients who underwent seton procedures with a sailor's knot were included in Group 1. Group 2 included those patients who underwent other seton procedures, including silk and penrose drain procedures. Groups were compared with regard to success rates and postoperative recurrence. RESULTS: There was no statistically significant difference between the groups in terms of the age, gender, fistula type and follow-up duration. Success rate in all patient was 88.6%, 91.2% in group 1 and 87.1% in group 2 (p=0.36). The number of patients with a kind of incontinence was 7 (7.1%), 3 (5.8%) in Group 1 and 4 (7.4%) in Group 2 (p = 0.297). CONCLUSION: There were no statistically significant differences with regard to complications and recurrences between the sailor's knot and the other seton tightening methods used for the treatment of anal fistulas. The sailor's knot is recommended with regard to its easy application and seton retightening with satisfactory outcomes.Öğe Pilonidal Sinus Disease: An Analysis of the Factors Affecting Recurrence(Lippincott Williams & Wilkins, 2021) Kanlioz, Murat; Ekici, Ugur; Tatli, Faik; Karatas, TurgayOBJECTIVE: o assess the success of treatment methods at reducing recurrence, the most important problem in pilonidal sinus disease (PSD), along with factors affecting the occurrence of PSD and posttreatment recurrence. METHODS; The researchers retrospectively analyzed files of patients treated for PSD between 2003 and 2018. Three study groups were created: G1, G2, and G3. G1 included all PSDs with recurrence, and a comparable number of cases without recurrence were selected randomly for the G2 group. The control group, G3, included healthy individuals without PSD. In all groups, the following were recorded: body mass index, skin color and oiliness, family history of PSD, hair overgrowth, smoking habit time spent sitting per day, and number of baths per week. The following were additionally recorded for G1 and G2 treatment methods, follow-up periods, pretreatment abscess(es), and time of onset of complaints before treatment The number of recurrences and the period between last treatment and recurrence were also recorded for G1. RESULTS: G1 comprised 234 patients: G2, 247 patients; and G3, 128 healthy individuals. The significant factors causing recurrence included body mass index, family history, bathing habits, hair overgrowth, skin color and oiliness, time spent sitting per day, smoking habit, abscessles), and duration of symptom(s)(P < .05). Limberg flap repair was the most successful treatment method. Sixty-three (27%), 135 (58%), and 185 (79%) recurrences occurred in the first 6 months, in the first year, and in the first 2 years, respectively. CONCLUSIONS: The researchers recommend Limberg flap repair for treatment. It is possible to reduce recurrence by taking preventable factors into consideration.Öğe The place of total testosterone in the etiology of pilonidal sinus disease(2020) Kanlioz, Murat; Karatas, Turgay; Ekici, Ugur; Tatli, FaikAim: There are lots of factors accused in the etiology of SPSD. One of those factors is hypertrichosis. Hypertrichosis is increased by high levels of testosterone. In our clinical practices, we observe the secondary effects of high testosterone levels in those with SPSD. Hence, we intended to analyze the correlation between testosterone and SPSD.Material and Methods: The first 200 patients who applied to General Surgery Clinic at Malatya State Hospital and were diagnosed with SPDS, were included in the study after being informed of our research and signing the informed consent form. The total testosterone (TT) levels of the patients were measured and recorded along with their demographic data. Also, a control group was formed of male and female patients without SPSD having the same demographic characteristics, whose TT levels were also subsequently recorded. The data from control and study groups were then compared and analyzed.Results: Of the 200 patients included in the study, 43 (21.5%) were female and 157 (78.5%) were male. Their overall mean age was 24.13±7.04 years and the median age was 22 years (min:14- max:50). The male-to-female ratio was 3.65. The rate of females and males who had high levels of TT was significantly higher than that of the control group (p0.001). Conclusion: We recommend measuring serum TT levels of patients who apply to hospital for SPSD. SPSD might be the first visible ring of the chain of diseases characterized by high levels of TT.Öğe Removing gallbladder from intra abdominal area by a different technique(2017) Gozeneli, Orhan; Tatli, Faik; Uzunkoy, Ali; Yucel, YusufAim: Laparoscopic cholecystectomy is a widely performed technique worldwide. The use of laparoscopic threaded holders for this is routine but takes a lot of time and may tear the gallbladder. There are no wide-mouthed and short endoscopic instruments that can be used for removing the gallbladder without perforation. We look at gallbladder removal methods that are quick and do not involve damage at the end of laparoscopic cholecystectomy.Materials and Methods: This prospective study was conducted on 30 laparoscopic cholecystectomy patients divided into two equal groups, one employing conventional laparoscopic cholecystectomy (CLC) and the other using a sponge holding forceps (SHF) (n=15, both groups) to demonstrate the effectiveness of our management. In the CLC group, the number of male patients was two (13.3 %) and female patients 13 (86.7%); in the SHF group, number of male patients was six (40%) and female patients nine (60%). When we compared the results statistically for bladder removal time, total operation time, gallbladder perforation, and wound infection, the p values were found to be 0.016, 0.182, 0.169, and 1, respectively.Results: Thirty patients were analyzed. The SHF group showed significantly better results than the CLC group for gallbladder removal time and better although not significantly better results for perforation of bladder, while there was no difference between the groups for wound infection.Conclusion: Removing the gallbladder with an SHF significantly shortens the duration of removal and also reduces perforations as compared to CLC.Keywords: Laparoscopic Cholecystectomy; Forceps; Techniques.Öğe Ruptured Hydatid Cysts into the Peritoneum: A Case Series(Urban & Vogel, 2010) Dirican, Abuzer; Yilmaz, Mehmet; Unal, Bulent; Tatli, Faik; Piskin, Turgut; Kayaalp, CuneytIntroduction: The rupture of a hydatid cyst into the abdominal cavity is a rare and serious complication. Methods: In this retrospective study, we evaluated ten patients who were surgically treated for ruptured hydatid cysts into the peritoneum at a university hospital in an endemic area between 2003 and 2008. Results: There were three female and seven male patients, with a mean age of 34.2 years (range 20-79). Ruptured cysts were located in the liver (7), pelvis (2), and spleen (1). Eight patients had other nonperforated hydatid cysts. Perforations were spontaneous in seven patients and traumatic in three. Patients' diagnoses were done with abdominal ultrasound (3), computed tomography (6), and laparotomy (1). The surgical treatment of perforated cysts were radical (pericystectomy) in one patient and conservative (partial pericystectomy) in the other nine patients. There was postoperative morbidity (surgical site infection) in one patient and one postoperative recurrence of disease in another patient. Mortality was seen in one patient 2 months after operation due to pulmonary hydatid cyst and infection. Conclusion: The rupture of hydatid cysts into the peritoneal cavity should be included in the differential diagnosis of acute abdominal pain in endemic areas. Perforation in a young patient may be the first presentation of hydatid cyst. Multiple hydatid cysts may be a predisposing factor for perforation. Location of the cyst on segment VI of the liver may be a predisposing factor as well. Emergency surgery is the main treatment for intraperitoneal rupture of hydatid cysts and medical treatment should be given postoperatively.Öğe Should colonoscopy screening be performed in patients with adnexal mass?(2018) Uyanikoglu, Hacer; Tatli, Faik; Uyanikoglu, AhmetAim: Besides primary ovarian tumor, a part of adnexal masses are metastatic colorectal cancers (CRC). Additionally, the risk of CRC is increased if the genitourinary cancers are present. In this study, we want to examine the separation of primer ovarian tumor and colorectal tumor metastasis and we investigated whether the routine colonoscopy is necessary in patients with adnexal mass. Material and Methods: This study included 58 women who underwent colonoscopy due to adnexal mass (Group 1) and 438 women who underwent colonoscopy for other reasons (Group 2). The colonoscopy results compared retrospectively in both groups between March 2014 and June 2016 at Harran University, Faculty of Medicine. Results: DThe mean age were 46.18 ± 16.89 (range 20-84) and 48.72± 17.95 (range 20-94) years in group 1 and 2, respectively. CRC was seen in two women (3.4%) and polyp in five (8.6%) in group 1. However, CRC was detected in 22 women (5%) and polyp in 71 (16.3) in group 2. The incidences of CRC and polyp were found to be lower in women with adnexal mass than group 2. Conclusions: The incidences of CRC and polyp were found to be lower in women with adnexal mass than those of without adnexal mass. Nevertheless, routine colonoscopy screening should be considered for women with adnexal mass due to the difficulties in the discrimination of primary and metastatic ovarian cancer in preoperative period.Öğe Single center experience in perianal fistula surgery(2018) Tatli, Faik; Ozgonul, Abdullah; Ciftci, Resit; Gumer; Mehmet; Erkmen, Firat; Karaca, Emre; Bardakci, OsmanAim: Perianal Fistula is the chronic stage of anorectal infection and is characterized by intermittent pain associated with purulent drainage or abscess formation followed by spontaneous abscess drainage. In this study, we aimed to investigate the recurrence rates according to the type of surgery performed for patients who underwent surgery for perianal fistula. Material and Methods: The records of 201 patients who underwent surgery in our hospital between the dates of January 2015 and May 2018 were analyzed retrospectively. In addition to the demographic information of the patients included in the study, their complaints, localization of the fistula, type of surgery performed, length of stay in the hospital, postoperative complications, and imaging methods were recorded. Loose or incisional seton stitch, fistulotomy and fistulectomy were performed according to the localization and the type of fistula. The seton stitch method was applied to complex fistulas, and the fistulotomy and fistulectomy methods were applied to simple fistulas. Results: Of the patients included in the study, 178 (88.5%) were males and 23 (11.5%) were females. Their mean age was 41.65 (27-77) years. Of the patients, 136 (67.7%) had complex and 65 (32.3%) had simple fistulas. The fistulas were intersphincteric in 90 (44,8%) patients, transsphincteric in 51 (25.4%) patients, suprasphincteric in 33 (16.4%) patients, and extrasphincteric in 27 (13.4%) patients. Conclusion: The complications and recurrence rates were found to be low postoperatively in all types of surgical procedures performed in our clinic. No statistically significant difference was found between the type of surgery and the recurrence rate.Öğe Ultrasonography in diagnosis of acute appendicitis(Edizioni Luigi Pozzi, 2016) Tatli, Faik; Ekici, Ugur; Kanlioz, Murat; Gozeneli, Orhan; Uzunkoy, Ali; Yucel, Yusuf; Dirican, AbuzerPURPOSE: Acute appendicitis is the most common surgical abdominal emergency. In the early diagnosis of acute appendicitis, the fact that there is no a sign which could be a reliable indicator in most of the patients increases the complications. In this study we aimed to search the relation between Ultrasonography(US) findings in patients with diagnosis of acute appendicitis and postoperative histopathologic investigation on remoced appendix.. MATERIALS AND METHODS: The files of 174 patients who came in our emergency department with lower right abdominal pain were studied retrospectively from January 2013 to May 2014. Of them, 26 patients were excluded, because these patients were not studied with US. US findings and histopathology reports of 148 patients with suspected acute appendicitis and studies preoperatively with abdominal US were enrolled. Greater than 6-mm diameter of the appendix under compression was accepted as positive sign of appendicitis in US. The demographic characteristics of the patients, US findings (acut appendicitis or not) and the pathology results were recorded on the standard proform. RESULTS: Of these 148 patients, 100 were acute appendicitis in preoperative US, and of these 100 patients, 93 histopathologic reports were acute appendicitis, 7 were normal appendices. The sensitivity of US was 75.6 % and specificity was 72 %. Positive predictive value (PPV) was 93 %, negative predictive value (NPTO was 14.6 % and the accuracy of US value was 81.7%. As a result, although US in diagnosis of acute appendicitis is a reliable technique, negative result doesn't mean no acute appendicitis. In order to determine an accurate diagnosis of acute appendicitis clinical and laboratoary findings should be assessed together.
