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Öğe Arterial myocardial revascularization using bilateral radial artery - 17 years after right pneumonectomy(Texas Heart Inst, 2004) Erdil, N; Nisanoglu, V; Toprak, HI; Erdil, FA; Kuzucu, A; Battaloglu, BWe report the case of a 51-year-old man who underwent arterial myocardial revascularization with the use of bilateral radial arteries, 17 years after undergoing a right pneumonectomy. We used a fast-track anesthesia protocol for the procedure. There was no perioperative complication, and postoperative recovery was uneventful. The patient was discharged from the hospital 5 days after the operation.Öğe Effectiveness of intravenous ephedrine infusion during spinal anaesthesia for Caesarean section based on maternal hypotension, neonatal acid-base status and lactate levels(Australian Soc Anaesthetists, 2002) Turkoz, A; Togal, T; Gokdeniz, R; Toprak, HI; Ersoy, OMaternal cardiovascular changes and neonatal acid-base status, including lactate levels, were assessed in 30 healthy women undergoing elective caesarean section under spinal anaesthesia. Patients were allocated randomly to receive IV ephedrine infusion (n = 15) (5 mg.min(-1)) immediately after the spinal injection or bolus administration of IV ephedrine (n = 15) (10 mg) in case of development of hypotension. Maternal and neonatal blood pressure, heart rate and acid-base status including lactate levels were compared between the groups. Systolic blood pressure in the bolus group was significantly lower when compared to the infusion group. Nausea was observed in one patient (6%) in the infusion group and nausea and vomiting were observed in 10 patients (66%) in the bolus group. Although umbilical arterial pH values were significantly lower in the bolus group, lactate levels were similar. In conclusion, ephedrine infusion prevented maternal hypotension, reduced the incidence of nausea and vomiting and led to improved umbilical blood pH during spinal anaesthesia for caesarean section.Öğe Effects of halotane, sevoflurane and isoflurane anesthesia on neuromusculer blocking effect of rocuromum(Prof Sci Publ, 1999) Togal, T; Türköz, A; Sahin, S; Toprak, HI; Ersoy, MÖ[Abstract Not Available]Öğe Hemodynamic, hepatorenal, and postoperative effects of desflurane-fentanyl and midazolam-fentanyl anesthesia in coronary artery bypass surgery(W B Saunders Co-Elsevier Inc, 2005) But, AK; Durmus, M; Toprak, HI; Ozturk, E; Demirbilek, S; Ersoy, MOObjective: The purpose of this study was to compare the hemodynamic, hepatorenal, and postoperative effects of desflurane-fentanyl and midazolam-fentanyl anesthesia during coronary artery bypass surgery. Design: Prospective study. Setting: University hospital. Participants: Sixty patients undergoing elective coronary artery bypass grafting surgery with ejection fraction more than 45%. Interventions: Anesthesia was induced with etomidate, 0.2 mg/kg, and fentanyl, 5 mu g/kg, in group D (n = 30) and with midazolam, 0.1 to 0.3 mg/kg, and fentanyl, 5 mu g/kg, in group M (n = 30). Anesthesia was maintained with desflurane, 2% to 6%, and fentanyl, 15 to 25 mu g/kg, in group D and midazolam infusion, 0.1 to 0.5 mg/kg/h, and fentanyl, 15 to 25 mu g/kg, in group M. Measurements and Main Results: Hemodynamic monitoring included a 5-lead electrocardiogram, a radial artery catheter, and a pulmonary artery catheter. Data were obtained before induction of anesthesia (t(0)), after induction of anesthesia (t(1)), after intubation (t(2)), after surgical incision (t(3)), after sternotomy (t(4)), before cardiopulmonary bypass (t(5)), after protamine infusion (t(6)), and at the end of the surgery (t(7)). Blood samples were obtained to measure total bilirubin, aspartate aminotransferase, gamma glutamyl transferase, lactate dehydrogenase, alkaline phosphatase, creatinine, and blood urea nitrogen just before induction of anesthesia and at the first, fourth, and 14th days postoperatively. Conclusions: Intraoperative hemodynamic responses were similar in both groups, and transient hepatic and renal dysfunctions were observed in the postoperative period in both groups. The extubation and intensive care unit discharge times were found to be shorter in the desflurane-fentanyl group. (c) 2005 Elsevier Inc. All rights reserved.Öğe Hyperbaric bupivacaine affects the doses of midazolam required for sedation after spinal anaesthesia(Lippincott Williams & Wilkins, 2005) Toprak, HI; Ozpolat, Z; Ozturk, E; Ulger, MH; Sagir, O; Ersoy, MOBackground and objective: Patients having spinal anaesthesia with hyperbaric bupivacaine may become sensitive to sedative drugs but no data exists about any dose-related effect of the local anaesthetic on the sedative requirement. We aimed to investigate whether hyperbaric bupivacaine dose in spinal anaesthesia has any effect on midazolam requirements. Methods: Sixty unpremedicated patients were allocated to three equal groups. Patients in Groups I and II received hyperbaric bupivacaine 0.5% 10 and 17.5 mg respectively for spinal anaesthesia and Group III was a control group without spinal anaesthesia. In Groups I and II, after the evaluation of sensory block, patients received intravenous midazolam I mg per 30 s until the Ramsay sedation score reached 3 (drowsy but responsive to command). In Group III, general anaesthesia was induced after sedation score had reached 3 using midazolam. The total dose of midazolam (mg kg(-1)) given to each patient, the level of sensory block and complications were recorded. Results: The level of sensory block was higher in Group II (T7) than Group I (T9) (P < 0.01). The doses of midazolam were 0.063 mg kg(-1) in Group I, 0.065 mg kg(-1) in Group II and 0.101 mg kg(-1) in Group III (P < 0.001). There was no correlation between level of sensory block and dose of midazolam in Group I (r = -0.293, P = 0.21) and Group II (r = 0.204, P = 0.39). Conclusions: Different doses of hyperbaric bupivacaine for spinal anaesthesia do not affect the midazolam requirements for sedation. However, spinal anaesthesia with hyperbaric bupivacaine with a maximum spread in the middle thoracic dermatomes may be associated with sedative effects and thus a reduced need for further sedation with midazolam.Öğe Remifentanil and acute intermittent porphyria(Lippincott Williams & Wilkins, 2002) Durmus, M; Turkoz, A; Togal, T; Koroglu, A; Toprak, HI; Ersoy, MO[Abstract Not Available]Öğe Sevoflurane as an alternative anaesthetic for electroconvulsive therapy(Lippincott Williams & Wilkins, 2005) Toprak, HI; Gedik, E; Begeç, Z; Öztürk, E; Kaya, B; Ersoy, MÖObjectives: The aim of this study was to investigate the effects of sevoflurane and propofol used in electroconvulsive therapy (ECT) on hemodynamic variables and duration of seizure activity and recovery profiles. Methods: Sixteen patients who were not premedicated, with a mean age 27.1 years, were enrolled in this prospective open trial, receiving a total of 64 ECT treatments. Each patient was given the following 2 anesthetic regimens in random order: In group S, anesthesia was induced with 7% sevoflurame in 100% oxygen at 6 L min (1) fresh gas flow until the loss of consciousness and 1.5 mg kg(-1) propofol in group P. Adequate muscle relaxation was achieved with suxamethonium, 1.0 - 1.2 mg kg(-1). Noninvasive mean arterial pressure (MAP) and heart rate (HR) values, duration of motor seizure activity, and recovery times were recorded. Results: The mean motor seizure duration was significantly longer with sevoflurane (mean [SD]: 43.09 [16.6] s) than with propofol (28.91 [7.9] s; P < 0.05). The MAP 1 minute and 10 minutes after ECT (10 1.25 [7.5] mm Hg and 100.16 [11.0] min mu g, respectively) was significantly increased compared with before ECT (94,56 [6.91 mm fig) in sevoflurane group (P < 0.05). Time to spontaneous breathing, eye opening and obeying commands, and changes in MAP and HR during and after ECT were similar in both regimens. Conclusion: Induction with 7% sevoflurane allows prolonged duration of motor seizures in ECT. We concluded that induction of anesthesia with sevoflurane inhalation is a reasonable alternative for patients undergoing ECT.