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    Computed Tomography Diagnostic Abilities for Open-Globe Injuries in Pediatric Versus Adult Patients
    (Lippincott Williams & Wilkins, 2021) Dikci, Seyhan; Yildirim, Ismail Okan; Firat, Murat; Firat, Penpe Gul; Demirel, Soner; Yilmaz, Turgut; Tuncer, Ilknur
    Objectives The aim of this study was to compare the role of computed tomography (CT) in the diagnosis of open-globe trauma and intraocular foreign body (IOFB) in pediatric and adult age groups. Methods Medical records of cases with open-globe trauma at Inonu University Hospital's Ophthalmology Emergency Service were retrospectively evaluated. Preoperative orbital CT images of the cases obtained at emergency services and their clinical and/or surgical findings were compared in pediatric and adult groups. Results We included 47 eyes of 47 cases aged 18 years and below (pediatric group) and 85 eyes of 82 cases over 18 years (adult group). The mean +/- SD age was 10.80 +/- 5.11 years (range, 2-18 years) in the pediatric group and 46.34 +/- 19.01 years (range, 19-82 years) in the adult group. Computed tomography images revealed 21.7% of the cases with corneal lacerations, 55.5% with scleral lacerations, and 91.6% with corneoscleral lacerations in the pediatric group, whereas the respective numbers were 48.4%, 66.6%, and 61.9% in the adult group. The detection rates of corneal penetrations and vitreous hemorrhage with CT were significantly lower in the pediatric group than in the adult group (P < 0.05). The CT scans diagnosed 66.6% of the pediatric cases and 90% of the adult cases with an IOFB. Conclusions Corneal lacerations and IOFBs can be missed, especially in the pediatric group, because the eye is smaller in adults. Pediatric patients with a history of ocular trauma should undergo an examination under general anesthesia followed by surgical exploration if necessary.
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    Corneal endothelial changes in long-term cannabinoid users
    (Taylor & Francis Ltd, 2018) Polat, Nihat; Cumurcu, Birgul; Cumurcu, Tongabay; Tuncer, Ilknur
    Purpose: The aim of this study was at evaluating the effects of long-term cannabis use on the corneal endothelial cells with the specular microscopy.Methods: The study enrolled 28 eyes of 28 patients diagnosed with cannabinoid use disorder. The cannabinoid group was selected among patients who had been using the substance for three days or more per week over the past one year. Thirty-two eyes of 32 age- and sex-matched healthy individuals enrolled as control group in the study. Corneal endothelial cell density (CD), coefficient of variation (CV) and hexagonal cell ratio (HEX) values were analyzed by specular microscopy.Results: The mean CD was 2900211 cells/mm(2) in the cannabinoid group and 3097 +/- 214 cells/mm(2) in the control group (p<0.01). There was a significant decrease in cannabinoid group. The mean CV was 29 +/- 7 and 27 +/- 4 in the cannabinoid and control groups, respectively (p>0.05). No significant difference was present between the cannabinoid and the control groups in terms of mean CV value. The mean HEX was 52 +/- 5% in the cannabinoid group and 53 +/- 10% in the control group (p>0.05). There was not a significant difference between the cannabinoid and the control groups in terms of mean HEX value.Conclusion: A significant decrease in CD was found in cannabinoid users compared the control group.