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Öğe Closure vs non-closure of peritoneum at caesarean section: Evaluation of pain(Taylor & Francis Inc, 2011) Atabekoglu, C. S.; Turkcuoglu, I.; Duru, B.; Sonmezer, M.; Suer, G.; Uysalel, A.; Koc, A.We evaluated the effect of closure or non-closure of parietal and visceral peritoneum during caesarean section (CS) on post-caesarean pain and analgesic requirement. A total of 94 primigravidas planned for elective CS were prospectively enrolled into closure (n = 46) and non-closure (n = 48) groups. Analgesia was provided by a patient-controlled analgesia pump (PCA) postoperatively. Pain was evaluated using a visual analogue scale (VAS) and verbal rating scale (VRS). Total dose of analgesics administered through PCA and times of analgesia demand and additional analgesics were also assessed. VAS and VRS scores were similar between the groups. The total dose of analgesics administered were similar (p - 0.095) between groups, however the mean number of analgesic demand (p = 0.020) and the additional analgesics (p < 0.001) were higher in the closure group. As a conclusion, the closure or non-closure of the peritoneum does not have any impact on postoperative pain intensity, however the analgesia demand and additional analgesia requirement decreases with non-closure.Öğe Follicular fluid adenosine deamines (ADA), superoxide dismutase and nitric oxide levels in GnRH agonist and antagonist cycles(Oxford Univ Press, 2012) Celik, E.; Celik, O.; Kumbak, B.; Yilmaz, E.; Turkcuoglu, I.; Simsek, Y.; Karaer, A.[Abstract Not Available]Öğe Lipid features of polycystic ovary syndrome under different diagnostic criteria(Oxford Univ Press, 2013) Celik, E.; Turkcuoglu, I.; Ata, B.; Karaer, A.; Kirici, P.; Berker, B.[Abstract Not Available]Öğe XPD and XRCC1 gene polymorphism in patients with normal and abnormal cervical cytology by pap smear(Verduci Publisher, 2012) Yilmaz, E.; Celik, O.; Celik, E.; Turkcuoglu, I.; Simsek, Y.; Karaer, A.; Otlu, B.AIM: The purpose of the present study was to identify the role of abnormalities in DNA repair pathways by measuring the XPD and XRCC1 gene polymorphisms. MATERIALS AND METHODS: Thirty-five patients with abnormal cervical cytology (study group) and 10 women with normal cytology (control group) were included in the study. The polymorphisms of XRCC1 Arg194Trp, XRCC1 Arg399Gln and XPD Lys751Gln genes were investigated from the blood samples. RESULTS: There was no statistically significant difference in allele frequencies of XPD gene among the groups (p = 0.097), while XRCC1R399Q gene polymorphism was strikingly more frequent in the study group than that of control cases (p = 0.029). The prevalence of XRCC1R194W gene polymorphism on the other hand, was similar between the groups (p = 0.579). CONCLUSIONS: Patients with abnormal and normal cervical cytology have similar XPD gene polymorphism. However, the frequency of gene polymorphism in XRCC1 Arg 399 Gln codon was significantly higher in abnormal cervical cytology group.