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Öğe Assessing Public Awareness and Perception of Teledermatology Via Survey(Mattioli 1885, 2024) Altunisik, Nihal; Gencoglu, Sule; Turkmen, Dursun; Sener, SerpilIntroduction:Teledermatology represents an alternative medical approach allowing for the remote assessment of a patient's clinical information without the need for face-to-face consultations. Objectives:This study aims to gauge the public's awareness and perception of teledermatology. Methods: This research employed a cross-sectional observational design. Data collection was executed using an online survey. Sociodemographic attributes of all participants, such as age, gender, and occupation, were recorded. The survey, designed using Google Forms, comprised two sections: demo-graphic information (5 questions) and queries related to teledermatology (10 questions). Questions and options in the survey were reviewed and revised by two dermatologists to eliminate potential misunderstandings, grammar, and other errors. Power analysis indicated a requirement of a minimum of 527 participants, given a 0.05 margin of error, 98% confidence level, and 0.50 response distribution. Results:A total of 873 individuals completed the survey- 47.7% were male and 52.3% were female. Students made up 48.1% of the participants, while 22.6% were civil servants. The Marmara Region had the highest participation rate at 47.7%. Remarkably, 41.9% of participants were unfamiliar with the term teledermatology. However, 57.2% expressed a preference for consultations via teleder-matology. Furthermore, 63.7% mentioned facing challenges when attempting to communicate with dermatologists for skin-related concerns. A notable 71.6% supported the formal implementation of teledermatology in our country. Conclusions:Our survey highlighted a limited awareness of teledermatology among participants, yet a majority showed a preference for teledermatology consultations. For a comprehensive understanding of public knowledge and perception towards teledermatology, more extensive, multicentric studies are necessaryÖğe Comment on 'Effects of the COVID-19 pandemic on head lice and scabies infestation dynamics: a population-based study in France'(Wiley, 2022) Turkmen, Dursun; Altunisik, Nihal[Abstract Not Available]Öğe Comment on 'Psychodermatology in psychiatry: awareness and education among psychiatry trainees'(Wiley, 2022) Ucuz, Ilknur; Turkmen, Dursun; Altunisik, Nihal[Abstract Not Available]Öğe Comment on 'Unexpected consequences of SARS-CoV-2 pandemic: scabies infestation'(Wiley, 2022) Turkmen, Dursun; Altunisik, Nihal[Abstract Not Available]Öğe Commentary on Evaluation of the efficacy of pro-yellow laser in the management of vascular skin disorders: Lymphangioma circumscriptum treated with 577-nm pro-yellow laser and Er:YAG laser(Wiley, 2022) Altunisik, Nihal; Turkmen, Dursun; Sener, Serpil; Alan, Saadet[Abstract Not Available]Öğe Commentary on Potential risk factors for Varicella-zoster virus reactivation after COVID-19 vaccination(Wiley, 2022) Turkmen, Dursun; Altunisik, Nihal; Altunisik Toplu, Sibel[Abstract Not Available]Öğe Commentary on The effect of 577-nm pro-yellow laser on demodex density in patients with rosacea(Wiley, 2022) Altunisik, Nihal; Turkmen, Dursun[Abstract Not Available]Öğe Comparison of patients' diagnoses in a dermatology outpatient clinic during the COVID-19 pandemic period and pre-pandemic period(Wiley, 2021) Turkmen, Dursun; Altunisik, Nihal; Mantar, Irem; Durmaz, Imge; Sener, Serpil; Colak, CemilAim In this study, we compared the current diagnoses of patients admitted to the dermatology outpatient clinic with the diagnoses during the non-pandemic period, and we examined the effect of COVID-19 on the patient profile. Methods Diagnoses were compared by examining the patient files of the 3-month period when the pandemic was influential in our country and the 2-week non-pandemic period corresponding to the same season a year ago. The outpatient diagnoses in the first month and the last month of the 3-month pandemic period were also compared. Results During the 3-month pandemic process, the most common reasons for applying to the outpatient clinic were acne, urticaria, psoriasis, and allergic/irritant contact dermatitis. Urticaria, psoriasis, allergic/irritant contact dermatitis, scabies, liken planus, mycosis fungoides, zona zoster, recurrent aphthous stomatitis and polymorph light eruption were statistically more common in the pandemic period. Moreover, acne, other eczematous dermatities, verruca, androgenic alopecia, and melanocytic nevus diagnoses were found to decrease statistically during the pandemic period when compared with the non-pandemic period. Conclusion Unlike other studies, the present study evaluated the patient diagnoses during the pandemic period and the period a year before and discussed the possible reasons for the changes in patient profiles.Öğe Cutaneous findings in children and adolescents with attention deficit and hyperactivity disorder(2020) Altunisik, Nihal; Ucuz, Ilknur; Turkmen, DursunAim: Attention Deficit and Hyperactivity Disorder (ADHD) is the most frequently diagnosed psychiatric disorder in children. Only one study was found in literature which examined cutaneous findings in ADHD so far. The aim of the present study is to evaluate the cutaneous findings of children and adolescents diagnosed with ADHD and to compare the incidence of these findings with healthy controls. Material and Methods: Forty-six patients diagnosed with ADHD according to The Diagnostic and Statistical Manual of Mental Disorders fifth edition (DSM-V) criteria and 50 healthy controls with no ADHD symptoms that had similar characteristics to the patient group in terms of sociodemographic characteristics such as age and gender were included in the study. All the patients underwent whole body dermatological examination and pathological findings in the skin, hairy skin and nails in the patient and control group were recorded. Results: The most common finding in the patient group was found as onychophagy and/or periungual skin biting with a rate of 76.1%. In addition, statistically significant difference was found between the two groups in terms of xerosis, prurigo and allergy history. Conclusions: It is important to be careful in terms of cutaneous findings that may accompany ADHD in terms of both early treatment and also for preventing possible complications. In addition, determination of these findings will guide future studies in terms of identifying the common aetiology of ADHD and some cutaneous diseases.Öğe Cutaneous reactions after COVID-19 vaccination in Turkey: A multicenter study(Wiley, 2022) Cebeci Kahraman, Filiz; Savas Erdogan, Sevil; Aktas, Nurhan Doner; Albayrak, Hulya; Turkmen, Dursun; Borlu, Murat; Arica, Deniz AksuObjectives In this study covering all of Turkey, we aimed to define cutaneous and systemic adverse reactions in our patient population after COVID-19 vaccination with the Sinovac/CoronaVac (inactivated SARS-CoV-2) and Pfizer/BioNTech (BNT162b2) vaccines. Methods This prospective, cross-sectional study included individuals presenting to the dermatology or emergency outpatient clinics of a total of 19 centers after having been vaccinated with the COVID-19 vaccines. Systemic, local injection site, and non-local cutaneous reactions after vaccination were identified, and their rates were determined. Results Of the 2290 individuals vaccinated between April 15 and July 15, 2021, 2097 (91.6%) received the CoronaVac vaccine and 183 (8%) BioNTech. Systemic reactions were observed at a rate of 31.0% after the first CoronaVac dose, 31.1% after the second CoronaVac dose, 46.4% after the first BioNTech dose, and 46.2% after the second BioNTech dose. Local injection site reactions were detected at a rate of 35.6% after the first CoronaVac dose, 35.7% after the second CoronaVac dose, 86.9% after the first BioNTech dose, and 94.1% after the second BioNTech dose. A total of 133 non-local cutaneous reactions were identified after the CoronaVac vaccine (2.9% after the first dose and 3.5% after the second dose), with the most common being urticaria/angioedema, pityriasis rosea, herpes zoster, and maculopapular rash. After BioNTech, 39 non-local cutaneous reactions were observed to have developed (24.8% after the first dose and 5% after the second dose), and the most common were herpes zoster, delayed large local reaction, pityriasis rosea, and urticaria/angioedema in order of frequency. Existing autoimmune diseases were triggered in 2.1% of the patients vaccinated with CoronaVac and 8.2% of those vaccinated with BioNTech. Conclusions There are no comprehensive data on cutaneous adverse reactions specific to the CoronaVac vaccine. We determined the frequency of adverse reactions from the dermatologist's point of view after CoronaVac and BioNTech vaccination and identified a wide spectrum of non-local cutaneous reactions. Our data show that CoronaVac is associated with less harmful reactions while BioNTech may result in more serious reactions, such as herpes zoster, anaphylaxis, and triggering of autoimmunity. However, most of these reactions were self-limiting or required little therapeutic intervention.Öğe The efficacy of a single-session pro-yellow laser in the treatment of facial telangiectasia(Springer London Ltd, 2021) Turkmen, Dursun; Altunisik, Nihal; Sener, SerpilFacial telangiectasia (FT) is a condition in which small dilated vessels visibly protrude on the surface of the skin. The aim of this study was to evaluate the efficacy and safety of a single-session pro-yellow laser in the treatment of FT and spider angioma (SA) to compare it with a limited number of studies conducted on this subject. In this pilot study, we reviewed 41 patients who admitted to our dermatology clinic with FT and SA and were treated by using pro-yellow laser. The efficacy of the treatment was evaluated using the recorded clinical information and digital camera images. The improvement was graded as complete (90-100%), very good (75-89%), good (50-74%), moderate (25-49%), and weak (< 25%). Of the 41 patients included in the study, 37 (90.2%) had FT and four (9.8%) had SA. Twenty-two patients were female and 19 were male. Pro-yellow laser therapy was generally well tolerated by patients, and minimal pain occurred during the application. In 1-month follow-up, good, very good, or complete recovery was achieved in 51.4% of the FT patients. The new pro-yellow laser only has a yellow light wavelength. Its unique wavelength at 577-nm yellow light is ideal for vascular lesions. In this study, 51.4% of the patients with FT achieved good, very good, or complete improvement after a single session of 577-nm pro-yellow laser, and complete improvement was achieved in all the four patients with SA.Öğe Evaluation of plasma zonulin level and its relationship with inflammatory cytokines in patients with vitiligo(Wiley, 2023) Arslan, Selami; Altunisik, Nihal; Turkmen, Dursun; Uremis, Muhammed M.; Sener, Serpil; Turkoz, YusufBackground It has been proven that there is an increase in intestinal permeability in some autoimmune diseases. In our study, we purposed to assess intestinal permeability in vitiligo disease by looking at zonulin levels. At the same time, we aimed to examine the correlation of inflammatory cytokines and lipopolysaccharide (LPS) levels with zonulin. Methods Forty-one patients and 41 healthy participants were involved in our study. Blood samples were taken from all patients and controls, and the levels of zonulin, tumor necrosis factor (TNF)-alpha, interleukin (IL)-6 and LPS were examined. Results The mean of zonulin in the patient group was found to be statistically higher than the control group (p < 0.05). A positive correlation was found between zonulin level and IL-6, TNF-alpha, and LPS levels (p < 0.05). TNF-alpha and LPS levels in the vitiligo group were significantly higher than in the control group, but there was no such significance in terms of IL-6 levels. Conclusion We think that serum zonulin level increases and intestinal permeability increases in vitiligo disease.Öğe Evaluation of serum TWEAK, TRAIL, and oxidative stress markers in rosacea patients(Wiley, 2022) Durmaz, Imge; Turkmen, Dursun; Altunisik, Nihal; Uremis, Nuray; Uremis, Muhammed Mehdi; Sener, Serpil; Turkoz, YusufBackground Rosacea is a chronic inflammatory skin disease of unknown pathogenesis. TWEAK and TRAIL are two cytokines thought to have a role in the pathogenesis of some inflammatory and autoimmune diseases. Aims The purpose of this study was to examine TWEAK and TRAIL serum levels and oxidative stress markers in patients with rosacea. Material and Method Forty rosacea patients and 40 sex- and age-matched healthy controls were involved in the study. Serum TWEAK and TRAIL levels were evaluated with ELISA kits. Serum total antioxidant status, total oxidant status, total thiol, native thiol, disulfide levels were evaluated, and oxidative stress index was computed. Results Serum levels of TWEAK, TRAIL, and oxidative stress markers did not differ statistically in the patients and controls. Both TWEAK and TRAIL levels in the patients were detected to be statistically higher in male than in female. Conclusion TWEAK and TRAIL may not have a systemic effect in rosacea, unlike other inflammatory diseases. More studies are needed to investigate the role of TWEAK and TRAIL in rosacea.Öğe Evaluation of temperament and character traits of patients with severe acne(Wiley, 2020) Altunisik, Nihal; Cansel, Neslihan; Turkmen, Dursun; Ucuz, Ilknur; Cumurcu, Hatice BirgulBackground Acne vulgaris (AV) is an inflammatory disease of the pilosebaceous unit. The relationship between personality and acne development has not been fully explained, and to the best of our knowledge, there are a limited number of studies in the literature evaluating temperament and character traits of individuals with acne. Aim The aim of this study is to evaluate temperament-character traits of individuals with severe acne and to compare them with healthy controls. Patients/Methods This study was conducted on 51 patients who admitted to the dermatology outpatient clinic with complaint of acne and were diagnosed with severe AV and 47 healthy individuals, as a control group. All individuals included in the study participated voluntarily. The forms including sociodemographic data, clinical information, and Temperament and Character Inventory (TCI) scores were applied to the patient and control groups. Results The scores of scales/subscales of exploration (NS1), persistence (P), responsibility (S1), purposefulness (S2), resourcefulness (S3), self-acceptance (S4), enlightened 2nd nature (S5), self-directedness (S), integrated conscience (C5), and cooperativeness (C) were statistically significantly lower, and the scores of scales/subscales of worry and pessimism (HA1), fear of uncertainty (HA2), shyness (HA3), fatiguability (HA4), and harm avoidance (HA) were statistically significantly higher in the patient group, in comparison with the control group. Conclusions When we evaluated the patients with severe acne in terms of temperament and character features, we concluded that individuals' feeling of discomfort about their appearance may cause them to be less sociable, more anxious, and to have low resourcefulness and virtues.Öğe Evaluation of the effect of 577-nm pro-yellow laser on demodex intensity(Taylor & Francis Inc, 2021) Altunisik, Nihal; Turkmen, Dursun; Sener, SerpilThe skin disease of the pilosebaceous unit created by demodex mites is called demodicosis. Recently, it has been brought to the agenda that laser therapies can be effective in reducing the intensity of demodex parasite. With this study, we aimed to evaluate the effect of pro-yellow laser applied to the face on the intensity of demodex parasite. Twenty-five patients who had referred to the dermatology polyclinic with a complaint of rash on the face and who had been given proyellow laser therapy during the past year were included in the study. Average pre-laser therapy demodex number per cm(2) was 3.9 +/- 5.0, while average post-therapy demodex number per cm(2) was 2.6 +/- 4.9 (p = .117). The 577-nm pro-yellow laser caused a change in demodex density. We found that the number of demodex following laser therapy decreased in some patients, while it increased in some others.Öğe Evaluation of the effects of COVID-19 pandemic on hair diseases through a web-based questionnaire(Wiley, 2020) Turkmen, Dursun; Altunisik, Nihal; Sener, Serpil; Colak, CemilAim Current quarantine conditions are a difficult process for individuals and can worsen the psychological state. Increased psychosocial stress can affect the course of many common stress-sensitive skin conditions. This study examined the possible effects of coronavirus disease 2019 (COVID-19) on hair and scalp diseases such as telogen effluvium (TE), alopecia areata (AA), and seborrheic dermatitis (SD) in individuals who had to stay at home for a long time and the patients' methods of dealing with these diseases. Methods The study was conducted using an online questionnaire. All the individuals were asked questions about pre- and post-pandemic TE, AA, and SD. Participants with complaints were asked what they did for treatment. Results During the pandemic, TE was seen in 27.9% of the participants, AA on the scalp was seen in 2.8%, AA on the face was seen in 2.5%, and SD was seen in 19.9%. Applying to a dermatologist for complaints during the pandemic was lower than before pandemic. TE was higher in women before and during the pandemic. Conclusion It was found that the rates of referring to a dermatologist for the complaints before the pandemic varied between 15% and 28% and that these rates decreased significantly during the pandemic (2.5%-12.5%).Öğe Evaluation of the relationship between androgenetic alopecia and blood groups and Rhesus factor(Wiley, 2021) Altunisik, Nihal; Turkmen, Dursun; Tetik, Burcu Kayhan; Sener, SerpilBackground/Aim Androgenetic alopecia (AGA) is the most common type of hair loss. Androgens and genetic factors are responsible for pathogenesis. Blood groups are genetic markers that are used to identify human gene variation. The aim of this study was to evaluate the blood group distribution in patients with AGA and to compare it with healthy population. Materials and Methods A total of 207 patients diagnosed with AGA in dermatology clinic and whose blood group records were available, between 2010 and 2019, were included in the study. Six hundred forty two healthy individuals who matched with the patient group in terms of age and sex, who attending to the family medicine outpatient clinic of our hospital in order to learn their blood groups were included as the control group. Results When the results were compared, no statistically significant difference was found between the two groups (P > .05). Conclusion We could not find any relationship between AGA and blood groups. However, in order to determine this relationship more clearly, further multicentre studies including more cases and investigating subgroups of the cases are needed.Öğe Exacerbations of generalized pustular psoriasis, palmoplantar psoriasis, and psoriasis vulgaris after mRNA COVID-19 vaccine: A report of three cases(Wiley, 2022) Durmaz, Imge; Turkmen, Dursun; Altunisik, Nihal; Toplu, Sibel Altunisik[Abstract Not Available]Öğe Investigation of monocyte HDL ratio as an indicator of inflammation and complete blood count parameters in patients with acne vulgaris(Wiley, 2020) Turkmen, Dursun; Altunisik, Nihal; Sener, SerpilAims Acne vulgaris is a common inflammatory skin disease that affects the pilosebaceous unit. Increased sebum production, hyperkeratosis in follicular infundibulum, inflammation andPropionibacterium acnesare among aetiological factors. Complete blood count (CBC) parameters are used as diagnosis biomarkers for many diseases related with inflammatory processes. Although monocyte/HDL ratio (MHR) has been defined as an inflammatory marker recently, we did not come across any studies about MHR in acne, which is known to be an inflammatory disease. The present study was conducted to compare CBC parameters and MHR levels in acne vulgaris patients and healthy controls (HCs). Methods Sixty-five acne vulgaris patients followed in our clinic between January 2018 and December 2019 and 36 HCs matching in terms of age and sex were included in the study. Patients and HCs were compared in terms of CBC parameters [neutrophil, monocyte, platelet, lymphocyte, neutrophil/lymphocyte (NLR), monocyte/lymphocyte (MLR), platelet/lymphocyte (PLR)], HDL and MHR ratio. Results When compared with the HCs, acne vulgaris patients had statistically significantly higher neutrophil, NLR ratio and HDL (P = .042,P = .011 andP = .014, respectively). No statistically significant difference was found between acne vulgaris patients and the HCs in terms of other CBC parameters and MHR ratio (P > .05). Conclusions We believe that prospective studies consisting of large patient series are needed to understand whether CBC parameters and MHR ratio can be used as an inflammatory marker in acne vulgaris patients.Öğe Investigation of the relationship between inflammatory blood parameters and rosacea and demodex infestation(Wiley, 2020) Altunisik, Nihal; Turkmen, Dursun; Sener, SerpilBackground Rosacea is a chronic inflammatory disease. Although the etiopathogenesis of the disease has not been established, it is known that inflammation plays a prominent role in the disease. Demodex mites have been thought to have a role in the pathogenesis of rosacea by causing the occurrence of inflammatory lesions. In the literature, many studies have reported that complete blood count (CBC) parameters have been used as diagnostic biomarkers in diseases associated with inflammatory process. Aims The aim of this study was to evaluate CBC parameters in rosaceous patients with and without demodex mite and to compare with healthy controls (HCs). Patients/Methods Ninety patients followed in our clinic between January and October 2019 and 62 healthy controls matching in terms of age and sex were included in the study. CBC parameters of the patients and the HCs were compared, retrospectively. Results There was no statistically significant difference in mean platelet volume (MPV), red cell distribution width (RDW), neutrophil lymphocyte ratio, monocyte lymphocyte ratio, and platelet lymphocyte ratio levels between all patients and HCs. RDW values were significantly lower in demodex (+) rosace group, when compared to demodex (-) rosace group and HCs. Conclusions The lower RDW levels in the demodex (+) group suggested that demodex mite did not have an increasing effect on inflammation and was effective in the disease through alternative pathways.
