Yazar "Turnaoglu, Hale" seçeneğine göre listele

Listeleniyor 1 - 2 / 2
  • Küçük Resim
    Öğe
    Are we on the side of over-diagnosis and treatment in BI-RADS 4A breast lesions?
    (2021) Avci, Tevfik; Erkent, Murathan; Turnaoglu, Hale; Borcek, Pelin; Kaya, Pelin; Karakaya, Emre
    Aim: In BI-RADS 4A lesions, a malignancy rate of between 2% and 10% has been detected. Many patients avoid biopsy even though biopsy is recommended because of its low malignancy rates. The aim of this study is to investigate the need for biopsy of patients with BI-RADS 4A lesions.Materials and Methods: 392 patients classified as BI-RADS 4A in our hospital between January 2011 and December 2019 were retrospectively analyzed. Clinical and demographic characteristics of the patients, complaints, physical examination findings, USG (ultrasound), MMG (mammography) and magnetic resonance imaging (MRI) findings, invasive surgical procedure or noninvasive procedure performed, pathology results were analyzed. Results: The mean age was 44.29 years (range, 15–93 years). The most common complaint was palpable mass (36.5%). While 88.5% of examined pathologies were evaluated as benign lesions, 7.1% were malignant. The rate of malignancy increased with age, and this difference was statistically significant (p = .000). Malignancy increases with lesions size but it was not statistically significant (p = .052). Palpable mass was more common in malignant lesions (55.2%) (p = .014). Comparing the radiological evaluations of BI-RADS 4A lesions with the post-biopsy pathology results, size increase, more than three lobulations, border irregularities, and cystic areas did not make a statistically significant difference in terms of benign, premalignant, and malignant pathologies; however, intraductal localization was observed more frequently in benign and premalignant lesions than in malignant lesions, and this difference was statistically significant (p = .003).Conclusion: We anticipate that the criteria developed with this study (more than three lobulations, border irregularity, cystic areas, and intraductal locations), applied to a wide range of patients, can be a source for future studies and can be used safely in other clinics. As a result, we strongly recommend biopsy for patients with postmenopausal and palpable masses if the criteria we used for detecting BI-RADS 4A are also present.
  • Küçük Resim
    Öğe
    Value of revised Geneva criteria and d-dimer levels in reducing overuse of pulmonary CT angiography in the diagnosis of pulmonary thromboembolism
    (2020) Turnaoglu, Hale; Ozcetin, Ayse; Keskin, Sefa; Becer, Berkay; Eybatova, Leyla; Durukan, Elif
    Aim: To investigate the applicability of modified Geneva score which is used to evaluate the clinical probability, with the d-dimer results, to reduce the overuse of pulmonary CT angiography, on patients with suspicion of pulmonary thromboembolism. Material and Methods: A total of 400 patients who had performed pulmonary CT angiography, with the suspicion of pulmonary thromboembolism, in the emergency department, were included in this retrospective study. The clinic and demographic datas of the patients were classified according to the modified Geneva score, and d-dimer values were recorded. Presence of pulmonary thromboembolism was investigated on the pulmonary CT angiography images accessed from Picture Archiving Communication Systems.Results: In a 33 (%8.25) of 400 patients, thromboembolism was detected in the pulmonary CT angiography. 20% (n=1), 8.8% (n=25), and 6.4% (n=7) of the patients, have been diagnosed pulmonary thromboembolism by CT, with the high, intermediate, and low clinical probability, respectively. One hundred ninety-seven (49.25%) out of 400 patients had d-dimer results. One (2.9%) out of 34 patients with a negative d-dimer value had thromboembolism in CT. The sensitivity, specificity, positive predictive value, and negative predictive value were calculated, as 78.8%, 28.1%, 9%, 93.6% of the modified Geneva score, and as 94.7%, 18.5%, 11%, and 97.1% of the d-dimer, respectively.Conclusion: In the diagnosis of pulmonary thromboembolism, modified Geneva score, and d-dimer test have high negative predictive values. Other clinic diagnoses can be considered primarily, in patients have low modified Geneva scores with negative d-dimer results. This may contribute to the reduction of the overuse of pulmonary CT angiography.