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    Detecting the presence of inflammation in fibromyalgia syndrome with neutrophil/lymphocyte ratio, platelet/lymphocyte ratio, and mean platelet volume
    (2021) Guntel, Murat; Uysal, Alper
    Aim: Our purpose was to determine the presence of inflammation in Fibromyalgia Syndrome (FMS), whether the parameters of neutrophil lymphocyte ratio (NLR) and platelet lymphocyte ratio (PLR) and mean platelet volume (MPV) can be used as inflammation markers.Materials and Methods: FMS patients who applied to Hatay State Hospital Physical Medicine and Rehabilitation Clinic in the last two years were analyzed retrospectively from the patient records. 92 participants were enrolled in the study, 43 of them were FMS patients, and 49 were healthy control group. Hemogram, glucose levels, hepatic panel and renal function tests, thyroid and parathyroid function testing, vitamin B12 and 25-hydroxyvitamin D, serum iron panel, folate, lipid panel, erythrocyte sedimentation rate (ESR), C-reactive protein, RF, Bucella agglutination test results were evaluated. Thus, patients with diseases that could affect NLR, PLR, and MPV were not enrolled in the study.Results: No significant difference between the groups in terms of gender distribution was found (p = 0.999). No significant difference between the groups in terms of age was found (p=0.327). When the groups were compared in terms of MPV, the values were found to be lower in the FMS group. Statistically significant difference was not found in both groups in terms of NLR, PLR, White blood count (WBC) and Platelet (PLT) levels (p=0.106; p=0.710; p=0.271; p=0.141, respectively).Conclusion: A significant difference was not found in both groups in terms of NLR and PLR, which were thought to be inflammation markers. The statistically significant higher values of mean ESR values in the FMS group indicate that inflammation may be present in the pathogenesis of FMS, but NLR and PLR cannot be used as indicators of inflammation, so correlating these rates with the severity of symptoms would be meaningless.
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    Effect of Octet-Truss Lattice Transition Geometries on Mechanical Properties
    (Springer, 2021) Emir, Ender; Bahce, Erkan; Uysal, Alper
    Additive manufacturing (AM) enables the production of lattice structures with unique properties using different production techniques. In this way, it is possible to obtain the desired mechanical properties by using different production parameters and lattice geometries. In this study, the load behaviors of the octet-truss lattice structure produced by fused deposition modeling (FDM) method with different transition geometries were investigated. Compression tests were carried out on lattice structures and also finite element method (FEM) was performed to determine the stress distributions and deformations. According to the results, it was observed that the transition geometry is an important parameter on the deformation patterns and stress distributions. In the lattice structure without transition geometry, plastic deformation occurred at low-stress values while the transition geometries exhibited plastic deformation at high-stress values. In addition, the effects of the transition geometries on the deformation types were observed. The deformation area on the samples having straight and inclined-transition geometries affected less area than the sample without transition geometry. It was found out that the stretch-dominated deformation type, which significantly affects the strength of the lattice structures subjected to load, was formed in all lattice structures.
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    Production and Cleaning of Lattice Structures Used in the Space and Aerospace Industry with Metal Additive Manufacturing Method
    (Springer, 2022) Akbay, Ozgun Ceren; Bahce, Erkan; Uysal, Alper; Gezer, Ibrahim
    Thanks to additive manufacturing, the use of lattice structures in aviation and space industry, especially heat exchangers, fuel nozzles and turbo machines located at the front of airplanes has increased. The production of computer-designed parts with the desired precision and geometry is important for concepts such as assembly, wear and surface properties. Problems encountered in selective laser melting (SLM) such as porosity, powder particle adhesions, affect assembly and surface properties. For this reason, cleaning is inevitable in sensitive systems used in the aerospace industry to have ready-to-use products after production or to prevent dust particles from breaking and causing problems in the workflow. To this purpose, chemical washing process was applied to improve the surface quality of the lattice structures and the healing effects of the acids used on the surfaces were investigated. In the experiment, nine lattice structures were produced from CoCr alloy and the effects of three different acid solutions prepared using hydrofluoric acid, nitric acid, sulfuric acid and hydrochloric acid on surface cleaning capacity were examined. The changes in the models immersed in the acid solution using the controlled immersion method for 180 seconds are presented comparatively. As a result of the experiment, it was seen that especially the solution containing hydrofluoric acid contributed to the improvement of the surface properties after production.