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    Measurement of Frontal Sinus Volume by Using Computed Tomography: A Stereological Study
    (Derman Medical Publ, 2015) Sapmaz, Hilal Irmak; Tugtag, Berin; Sapmaz, Emrah; Kose, Evren; Ozbag, Davut; Uysal, Murat
    Aim: Paranasal sinuses are the anatomic regions that are frequently affected by allergic diseases and infections, thus it is substantial to comprehend the morphological structure of these regions for surgery. The aim of our study is to obtain stereological evaluation of frontal sinus volumes of female and male individuals by using computerized tomography (CT). Material and Method: This study assessed the CT images of 140 cases (70 male, 70 female) were at the age of 20 to 60 years and didn't have a disease of frontal sinus. Frontal sinus volumes were calculated stereologically on coronal plane sections by using planimetric method via Cavalieri principle. Results: When the data of male and female individuals were compared statistically; it was observed that frontal sinus volumes of men were larger. Average frontal sinus volume of women was 4,04 +/- 1,84 cm(3) and it was 7,02 +/- 2,78 cm(3) for men. Discussion: Significant advancement was obtained for paranasal sinus imaging by the use of CT, magnetic resonance imaging and three dimensional imaging techniques. In our study, frontal sinus volumes of adult individuals were measured by using planimetry method and it was detected significantly larger in men. Since frontal sinus is one of the paranasal sinuses that reveal asymmetrical development, it is clinically important to seek out its volume. In conclusion; we think that determination of the frontal sinus volume will make a major contribution to physicians for inflammatory sinus diseases, frontal sinus traumas and endoscopic sinus surgery.
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    Orthopedic trauma or surgery does not effect on cognitive or behavioral capability of rats
    (2020) Aytekin, Kursad; Uysal, Murat
    Aim: The aim of this study is to investigate the probable effects of orthopedic trauma/surgery on anxiety, memory and learning capability in rats. Material and Methods: Twenty-one Wistar albino rats grouped into three as control, sham operated, and tibia fracture. In control group, any surgery or fracture was done whereas in sham group the tibia of rats was fixed with intramedullar Kischner wire. In tibia fracture group, a closed fracture was occurred with Bonnarens and Einhorn's guillotine device then intramedullar Kischner wire sends to tibia. All rats were evaluated for memory, anxiety, and learning via behavioral tests respectively; water-maze test, elevated plus arm test and shuttle box test. Results: One month after the fractures were done and the bone healing was seen on X-ray at all rats. According to the behavioral tests results, there was not any statistically difference between groups in terms of anxiety, learning capability, locomotor activity and memory (p>0.05). Conclusion: Our results showed that, the orthopedic trauma or surgery itself does not affect the anxiety, learning capability, locomotor activity and memory in rats.