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    Effect of early tail-docking on luteinizing hormone pulse frequency in fat-tailed Tuj ewe-lambs
    (Shiraz Univ, 2013) Kaya, M.; Cenesiz, M.; Onder, F.; Uzun, M.; Yildiz, S.
    The aim of the study was to investigate the effect of tail-docking on the LH pulse frequency in female Tuj lambs. Twelve female lambs were assigned into two equal groups. A rubber ring was applied to the base of the tail for shedding off. Blood samples were collected for 8 h in the 4th and 8th months of age to determine pulsatile secretion of LH. Starting from the age of 6 months, blood samples were taken thrice weekly for progesterone analyses. There was no LH pulse in the first LH analysis but the pulses were observed in both groups in the second LH analysis. However, number of pulses was not different between groups. The plasma progesterone level was less than 1 ng/ml throughout the breeding season. In conclusion, there was no effect of the tail-docking on pulsatility of LH in fat-tailed female lambs.
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    IS THERE A RELATIONSHIP BETWEEN SERUM IGF-1 AND THYROID NODULE, THYROID OR OVARIAN VOLUME IN POLYCYSTIC OVARIAN SYNDROME?
    (Editura Acad Romane, 2021) Topaloglu, O.; Evren, B.; Uzun, M.; Yologlu, S.; Guldogan, E.; Sahin, I
    Context. Studies investigating the association between serum IGF-1, and thyroid nodule, ovarian or thyroid volume in polycystic ovarian syndrome (PCOS) are limited. Objective. We aimed to analyze the association between serum IGF-1 level, and ovarian or thyroid volume, or thyroid nodule in PCOS. Design. The study was performed between June 2017 and August 2019 as prospective design. Subjects and Methods. Adult females with new-onset PCOS were included. The patients having comorbid illness, or using medication were excluded. Basic tests, thyroid and ovarian sonography were performed. The patients were grouped according to thyroid nodule(absent/present) and ovarian volume (<10mL/>= 10mL). We planned to find a positive association between IGF-1, and thyroid nodule, thyroid or ovarian volume in PCOS. Results. Of total 118 patients, 11(9%) had thyroid nodule. The patients with thyroid nodule had a higher ovarian volume (p=0.006). No correlation was found between GH or IGF-1, and thyroid or ovarian volume. IGF-1 was not a predictor for thyroid nodule or higher ovarian volume. Thyroid nodule was a significant predictor for higher ovarian volume. Conclusion. Our study is the first to analyze the association between IGF-1 and thyroid nodule in PCOS. We found that thyroid nodule was associated with thyroid and ovarian volume, but IGF-1 was not associated with thyroid nodule, thyroid or ovarian volume.