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    Assessment of upper airway obstruction in children with specific learning disorder
    (2020) Uzun Cicek, Ayla; Bora, Adem
    Aim: A growing number of findings suggest that there is an important relationship between upper airway obstruction (UAO) and specific learning disorder (SLD). However, existing evidence is limited to very few studies. We, thus, aimed to explore chronic UAO conditions in children with specific learning disabilities.Materials and Methods: This study involved seventy-seven children aged 7 to 10 years with SLD and eighty-six healthy children matching in age and gender. Psychiatric disorders were diagnosed through the Diagnostic and Statistical Manual of Mental Disorders (DMS-5) Criteria. Porteus Maze Test and Kent-EGY test were used to assess the intelligence of the participants. The diagnoses of UAO were made by a physical examination, a detailed otorhinolaryngologic examination, the anamnesis and clinical history, anterior rhinoscopy, and flexible endoscopic nasopharyngoscopy according to the type of UAO.Results: The rates of having at least one pathology causing UAO and secondary sleep difficulties due to UAO were significantly higher in children with SLD compared to controls. The severity of SLD was significantly associated with the severity of UAO and the presence of secondary sleep difficulties, but not the presence of UAO. The verbal and total IQ scores were significantly affected by the presence and severity of UAO, while the presence of secondary sleep difficulties significantly impacted all IQ scores.Conclusion: Parents, teachers, otorhinolaryngologists, child psychiatrists, and pediatricians should be aware that the association between learning disorders and UAO. It also would be advisable to screen children with learning disorders in terms of UAO, and vice versa.
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    Clinical characteristics according to sex and symptom severity in children with selective mutism: a four-center study
    (Taylor & Francis Ltd, 2023) Dogru, Hicran; Ucuz, Ilknur; Uzun Cicek, Ayla; Comertoglu Arslan, Semiha
    IntroductionClinical information regarding selective mutism (SM), a persistent and debilitating psychiatric disorder, in children is extremely limited. We aimed to examine sociodemographic characteristics and comorbid psychiatric conditions and identify clinical variables associated with sex and SM severity among children with SM.MethodsWe analyzed the medical records of 49 children who received treatment for SM in four different tertiary hospitals in Turkey between 2016 and 2021. Children's charts were reviewed to examine clinical characteristics, comorbidities, and response to treatment.ResultsThirty-one children were female, and 18 were male (female:male ratio is 1.7:1). Most children (73.5%) with SM displayed onset of SM in 3-6 years. However, most children (57.1%) were diagnosed between the ages of 7-11. The mean time from onset to diagnosis was 1.69 +/- 1.37 years. Females displayed a later onset of SM (6.42 +/- 2.40 vs. 4.89 +/- 0.96; p= 0.013) and higher comorbidity rates (71% vs. 38.9%, p= 0.039) than males. The vast majority of children received two or more psychiatric diagnoses. Children in the severe group had a longer duration of illness, higher rates of psychiatric comorbidity, speech delay, and treatment resistance.ConclusionOur study suggests that SM may have different clinical features according to sex and symptom severity of SM. More information about children with SM is needed to understand the development and maintenance of SM.
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    Frequency of headache and related clinical factors in children and adolescents with tic disorders
    (2020) Uzun Cicek, Ayla; Ucuz, Ilknur; Bolayir, Ertugrul
    Aim: Only a few studies have investigated the comorbid headache in children with tic disorders (TD). In this study, thus, we aimed to examine the frequency and clinical correlates of comorbid headache in TD.Material and Methods: The sample consisted of 98 children and adolescents aged 6–16 years with a diagnosis of any tic disorder and 108 healthy children and adolescents matched for age, gender and sociocultural characteristics. All participants underwent a semi-structured psychiatric interview to establish a psychiatric diagnosis. The diagnosis of headache was made according to the third edition of the International Classification of Headache Disorders criteria. Also, a specially prepared personal information sheet and Yale Global Tic Severity Scale were applied.Results: Children and adolescents with TD had a significantly higher frequency of headache compared to those in the control group (44.9% vs. 22.2%, p=0.001). The most common type of headache in both groups was migraine. We determined that the rate of diagnosis of chronic tic disorders, percentage of the presence of vocal tics, severity of tics, the proportion of patients taking pharmacotherapy for tics, and the rate of psychiatric comorbidity were significantly higher in patients with a headache than those without headache.Conclusion: The results of our study confirm studies showing suggesting a possible relationship between TD and headache, and supports the proposition that headache is a comorbidity of TD. However, further studies exploring the mechanisms of this relationship are required. It also would be advisable to screen children with TD in terms of headaches.