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Öğe A cross-sectional chart of stretched penile length for Turkish children aged 0-6 years(2020) Gul, Yahya; Yakar, Burkay; Saglam, HalilAim: Examination of the external genitalia is an important step in the routine child examination. Penile lengths of infants of different ethnicities show statistically significant differences. Therefore, standard values for penis sizes in healthy newborns and children in each country should be established. The aim of this study was to establish a normal range of 0 to 6 aged healthy children stretched penile length and to evaluate the relationship between stretched penis length and height. Material and Methods: This was a cross sectional observational study, carried out at tertiary university hospital in Turkey. Total of 948 healthy children aged 0-6 years were included in the study. Stretched penile length (SPL) was measured from the pubic ramus to the tip of the glans. The mean stretched penil length and Stretched penile length / height ratio for each age group were calculated and percentile curves were determined for both group.Results: The stretched penile length was 2.76 ± 0.42 cm in full-term newborns (n = 101). The SPL ranged from 2.98 ± 0.44 cm to 3.40 ± 0.56 cm in aged 1.1 to 12 months (n=309). The SPL ranged from 3.62 cm to 4.96 cm in children aged 12.1 to 72 months (n=538). There was a statistically significant correlation between mean stretched penis length and height (p=0.001).Conclusion: These data may be useful in the follow-up of healthy children. Furthermore, this study sets an example for larger-scale studies performed using older participants population in a larger geographic region.Öğe Frequency of aspirin use in patients with type 2 diabetes: Is there any effect of concomitant diseases?(2019) Azakoglu Karaca, Asli; Yakar, BurkayAim: Current guidelines recommend the use of low-dose aspirin in diabetic patients with increased cardiovascular disease risk with no risk of bleeding to prevent cardiovascular events. The aim of this study was to investigate the frequency of aspirin use in Type 2 Diabetes Mellitus and the effects of concomitant diseases.Material and Methods: Our retrospective and cross-sectional study was planned of data for rate of aspirin use in Type 2 Diabetes mellitus patients. In our study, the socio - demographic characteristics of the participants, their concomitant diseases with Type 2 DM and the drugs they used were questioned. Chi-square test was used for the analysis of categorical variables. P0.05 was considered statistically significant.Results: The mean age of the 910 participants was 57.27±10,00. 64.2% of the participants were female and 35.8% were male. Hypertension was the most common concomitant disease in type 2 DM. The prevalence of aspirin use was found to be %38.6. There is a statistically significant difference between aspirin use rates according to genders (p 0.05). Aspirin use was significantly higher in those who quit smoking and those with concomitant disease with type 2 DM. (p0.05). Conclusion: The rate of aspirin use in our diabetic group was insufficient. In order to increase the use and awareness of aspirin, the factors affecting the use of aspirin should be investigated.Öğe The relationship between betatrophin levels and HbA1c(2020) Kilicoglu, Mesut; Solmaz, Ihsan; Yakar, Burkay; Onalan, Erhan; Gursu, FeritAim: In our study, we first aimed to investigate the effect of betatrophin in uncontroled diabetes patients with HbA1c above 14. Another focus of our study is the effect of betatrophin levels on the biochemical parameters of the patients. Material and Methods: This is an observational study with a prospective case-control design. The study was carried out between July 2018 and November 2018 at the internal medicine clinic of the tertiary university hospital. Our study was conducted with participants divided into 3 groups. Group 3 (uncontrolled T2DM) consisted of 40 participants who met the study criteria and HbA1c above 14% . Group 2 (controlled T2DM) consisted of 40 participants who met the study criteria and HbA1c below %10 and the group 1 (control group) consisted of 40 people who did not have a history of diabetes mellitus.Results: There was no statistical difference in age and sex between the 3 groups included in the study. Betatrophin levels of patients with uncontrolled diabetes were significantly higher than control group and controlled diabetic group.(p0.001). HbA1c value of the participants was found to have a significant effect on betatrophin level, unlike other parameters.(p0.001).Conclusion: We found higher betatrophin levels in the group with uncontrolled diabetes in our study. There was no significant difference in betatrophin levels between the controlled T2DM group and the healthy group. Our data found that betatrophin level showed a significant positive correlation with HbA1c level.