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Öğe A 9-year follow-up of a girl with pyridoxine (vitamin B6)-dependent seizures: magnetic resonance spectroscopy findings(Verduci Publisher, 2012) Dogan, M.; Dogan, D. Gumus; Kahraman, A. S.; Ozcan, O.; Yakinci, C.; Alkan, A.Being an extremely rare condition makes the diagnosis of pyridoxine-dependent seizures (PDS) difficult. Early diagnosis of PDS is very important to prevent unwanted clinical outcomes. Elevated levels of glutamate and decreased levels of gamma-aminobutyric acid (GABA) in the frontal and parietal cortices are detected in this disorder. Here we present an 18 year old girl with PDS, who was reported 9 years ago with Magnetic Resonance Spectroscopy (MRS) findings. Present and past MRS findings showed a decrease in N-acetyl-aspartate-to creatine ratio on MRS. In this case it is surprising that neuronal damage has been preceded despite the administration of accurate treatment. That can be because of delay in treatment and/or under treatment.Öğe Congenital brucellosis: case report(Maney Publishing, 2010) Dogan, D. G.; Aslan, M.; Menekse, E.; Yakinci, C.A 6-hour-old infant was admitted with severe respiratory distress and hepatosplenomegaly. Her mother had arthralgia for 4 weeks in the 7/8th month of pregnancy and the infant was born at 31 weeks. Brucella spp was detected in blood culture and serology in mother and infant, supporting the diagnosis of brucellosis with presumed transplacental transmission.Öğe Diffuse edema and bilateral massive pleural effusion as the presentation of systemic lupus erythematosus(Sage Publications Ltd, 2011) Aslan, M.; Bicak, U.; Dogan, D. G.; Dogan, M.; Yakinci, C.A rare case of systemic lupus erythematosus (SLE), with massive bilateral pleural effusions and generalized edema as the first manifestations, is reported. The patient was a previously healthy 13-year-old boy. He presented with a history of fever, lack of appetite, gradually increasing fatigue, cough, diffuse edema, and moderate dyspnea. He responded well to corticosteroids with resolution of the pleural effusions, and edema. SLE should always be kept in mind in cases of massive pleural effusions and/or diffuse edema, even in the absence of other clinical manifestations of the disease. Lupus (2011) 20, 308-310.Öğe HANHART SYNDROME(Medecine Et Hygiene, 2010) Dogan, D. G.; Dogan, M.; Aslan, M.; Menekse, E.; Yakinci, C.Hanhart syndrome: We report on a male infant with Hanhart Syndrome. It is classified in oromandibular limb hypogenesis syndromes which are a group of rare conditions involving congenital malformations of tongue, mandible, and limbs.Öğe Mapping of Blood Coagulation via Image Processing Method(Ieee, 2015) Onar, B.; Bayindir, M. I.; Bilgili, H.; Erkurt, M. A.; Yakinci, C.; Yakinci, M. E.Biomedical applications based on image process algorithms are developed to aid doctors for diagnostic of some diseases. Several conventional tests are available about measuring blood coagulation such as PTZ, aPTZ, PTZ-INR. These tests are performed before every surgical operation even during some critical operations especially in cardiovascular and liver operations. Then, images are taken by a microscope connected to a computer in every 15 seconds, in such a way that 45 images are obtained till end of coagulation. These images are processed in an image processing algorithm in Matlab software. Hence, a graphical representation is produced for every subject. Results obtained from the proposed method prove that it can be a useful alternative to conventional methods.