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Öğe Anesthesia management of open tracheostomy patients: A single center experience(2019) Karaaslan, Erol; Yalin, Mehmet RidvanAbstract: The purpose of the present study of ours was to evaluate anesthesia management and complications in open technique tracheostomy cases. This study was conducted in 105 patients who underwent tracheostomy. The patients were retrospectively screened. The demographic data, anesthesia management, length of hospital stay, Intensive Care Unit stay, mortality, perioperative, postoperative, and early complications of the patients were evaluated. The average age of the patients was 20-91 (60±14.92) years. ASA scores were as follows: 54 cases (51.4%) were ASA II; 45 cases (42.8%) were ASA III; and 6 cases (5.7%) were ASA IV. The most common complaints of the patients were as follows: Head-neck tumor in 75 cases (71.4%). The anesthesia methods were as follows: General anesthesia in 92 cases (87.6%), and sedoanalgesia in 13 cases (12.4%). The most common complications were as follows: Bleeding in 5 patients (4.7%) in the perioperative period; and respiratory failure in 19 patients (18.1%) in the postoperative period. Postoperative mortality was seen in 6 cases (5.7%). There was a statistically significant difference between the mortality rates, hospital stay, and age (P: 0.008) (P<0.0001). In the present study of ours, it was shown that hospital stay and age factor had a significant effect on mortality in tracheostomy cases. We believe that sedoanalgesia, which preservesÖğe Anesthesia Management of Pediatric Burn Patients: A Retrospective Analysis of Patients Treated in a University Hospital(Galenos Publ House, 2025) Karaaslan, Erol; Yalin, Mehmet Ridvan; Ozkan, Ahmet Selim; Begec, Zekine; Demircan, MehmetIntroduction: This retrospective study focused on pediatric patients who underwent surgery for burns under anesthesia in our hospital and assessed demographic data, anesthesia management, and risk factors for mortality. The study comprised 278 pediatric patients who were treated in our unit, a major center for burn admissions, between January 2012 and May 2021. All the patients had burns involving more than 10% of the total body surface area. Methods: Data on the following were collected: patient age, sex, and ethnicity; anesthesia and airway management- and surgeryrelated procedures; and laboratory test results. The data on the fatal and non-fatal cases and those with/without head and neck burns were compared. Results: The mean age of the patients was 56.8 +/- 42.9 months (range 1-204 months). The number of patients with flame burns was statistically, significantly higher than the number of patients with liquid and electrical burns (54.7%, 37.1%, and 8.3%, respectively) (p<0.001). Albumin (p=0.046), platelet (p=0.005), and calcium (p=0.001) values were significantly lower, and blood urea nitrogen (p=0.024) and C-reactive protein (p=0.001) values were significantly higher in mortality cases than in non-mortality cases. Patients who died were statistically significantly younger (p=0.023). For airway management, endotracheal intubation and sugammadex were used significantly more often for head and neck burns than for other types of burns (p<0.001). Conclusion: Appropriate preoperative preparation, including consideration of the anesthetic method and potential complications that may develop during the surgery, is needed in pediatric burn cases. Anesthesia and airway management are important in managing pediatric burn patients.Öğe Anti-inflammatory Effects and Pharmacokinetics of Bupivacaine in Transversus Abdominis Plane Block for Living Liver Donors: A Prospective Randomized Clinical Trial(Elsevier Science Inc, 2025) Yalin, Mehmet Ridvan; Erdogan, Mehmet Ali; Ucar, Muharrem; Uremis, Muhammed Mehdi; Colak, Yusuf Ziya; Ozdemir, Emine; Ugur, YilmazObjective. Transversus abdominis plane (TAP) blocks have been reported to decrease postoperative pain and opioid use. Local anesthetics modulate the local and systemic inflammatory reaction. Our aim was to examine the effect of TAP block with bupivacaine on the antiinflammatory response in living liver donors. Methods. The randomized prospective clinical study was carried out on 72 living liver donors, aged 18 to 65 scheduled for right hepatectomy. TAP blocks were performed bilaterally with ultrasound guidance using 1.5 mg/kg of 0.5% bupivacaine for group 2. Group 1 patients were the control group. In both groups, blood samples were obtained preoperatively, 30 minutes and 2, 6, and 24 hours after the injection for cytokine measurement. In group 2, to examine the plasma bupivacaine level, blood samples were obtained preoperatively as well as 30 minutes and 1, 2, 6, 12, and 24 hours after injection. The primary outcome was to assess the effect of TAP block on the inflammatory response using cytokine levels. Results. No difference was observed between cytokine levels (tumor necrosis factor-alpha, interleukin [IL]-1 and IL-6) between groups Significant positive correlations were observed between the plasma bupivacaine concentration and IL-1 and IL-6 levels at 2, 6, and 24 hours. Conclusion. Although the TAP block did not affect the levels of cytokines significantly, a significant association was seen between the concentrations of plasma bupivacaine and the levels of IL-1 and IL-6 at 2, 6, and 24 hours. In contrast, the clinical significance of this association is still under investigation.Öğe Successful difficult airway management of a child with Coffin-siris syndrome(Wiley, 2017) Ozkan, Ahmet Selim; Akbas, Sedat; Yalin, Mehmet Ridvan; Ozdemir, Emine; Koylu, ZeynepKey Clinical Message Management of airway in patients who have Coffin-Siris syndrome (CSS) is often problematic because most of these patients have difficult airway. NTI via C-MAC VL is an useful alternative to direct laryngoscope for orotracheal intubation in airway and anesthetic management in a case of CSS. Alternative airway devices should be readily available.
