Yazar "Yalta, Kenan" seçeneğine göre listele
Listeleniyor 1 - 3 / 3
Sayfa Başına Sonuç
Sıralama seçenekleri
Öğe Coronary collateral circulation: Any effect on P-wave dispersion?(Sage Publications Inc, 2008) Aslan, Halil; Turgut, Okan; Yalta, Kenan; Yilmaz, Mehmet B.; Ozdemir, Ramazan; Ermis, Necip; Sezgin, Alpay T.Coronary collateral circulation determines the severity of ischemic myocardial damage. Increased P-wave dispersion is an independent predictor for atrial fibrillation. Consistent evidence is little about the relation between coronary collateral circulation and arrhythmia risk. In this article, the effect of coronary collateral circulation on P-wave dispersion was evaluated. Collateral grade and p-wave dispersion were ascertained in 100 patients with >= 85% diameter stenoses in left anterior descending or right coronary arteries. Left ventricular function score was also determined in all patients. Coronary collateral circulation was absent in 32 patients, whereas 68 patients had coronary collateral circulation. Patients with collateral grade A had greater left ventricular function score than did patients with collateral grade 0 (P = .048). However, there was no significant difference between P-wave dispersion of patients with and without coronary collateral circulation (P = .45). The presence of coronary collateral circulation failed to exert a beneficial decreasing effect on P-wave dispersion.Öğe Protective Effect of Amifostine on Radiotherapy-Applied Cardiovascular Tissue(Kare Publ, 2025) Taylan, Gokay; Caloglu, Murat; Caloglu, Vuslat Yurut; Yalta, Tulin; Aydogdu, Nurettin; Yalta, Kenan; Aktoz, MeryemBackground: The present study evaluates the protective effect of amifostine (AMI) on acute toxicity in large vessels and the heart in rats with radiotherapy (RT) applied to the thorax. Methods: Twenty-one Wistar albino rats were randomly assigned to 3 groups: Alone RT (n = 7), amifostine plus RT (AMI+RT, n = 7), and control (n = 7) groups. The rats in the RT and AMI+RT groups received a single dose of 20 Gy radiation to the entire thorax. Prior to irradiation, AMI was administered intraperitoneally at a dose of 200 mg/kg, 30 minutes before the procedure. Five days after irradiation, the levels of p53, CD68, and COX in the vascular tissue (aorta) were measured, along with the levels of malondialdehyde (MDA) and glutathione (GSH) in the aortic and heart tissues. Results: The results showed that the level of MDA significantly increased after irradiation, but GSH levels did not change (P < .001 and P = 0.138). Malondialdehyde levels were significantly reduced by AMI, and GSH levels increased (P = .031 and P = .007). When comparing the control group with AMI + RT, MDA and glutathione levels were similar (P = .314 and P = .136). Histopathological evaluation revealed increased cellular inflammation (P = .002) and vascular damage (P = .015) in aortic tissue after thoracic RT irradiation, but no difference in terms of myofibrosis (P = .901) in heart tissue. Conclusion: AMI has a radioprotective and antioxidant effect against RT-induced cardiovascular toxicity.Öğe Reply to Letter to the Editor: Comment On: Protective Effect of Amifostine on Radiotherapy Applied Cardiovascular Tissue(Kare Publ, 2025) Taylan, Gokay; Caloglu, Murat; Caloglu, Vuslat Yurut; Yalta, Tulin; Aydogdu, Nurettin; Yalta, Kenan; Aktoz, Meryem[No abstract available]
