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    Effects of short-term pre-competition weight loss on certain physiological parameters and strength change in elite boxers
    (Public Library Science, 2024) Yasul, Yavuz; Akcinar, Faruk; Yasul, Muhammet Enes; Kurtoglu, Ahmet; Eken, Ozgur; Badicu, Georgian; Ardigo, Luca Paolo
    Background Athletes in certain sports aim to gain an advantage by competing in a lower body mass class instead of competing in their own body mass class. This study aims to reveal certain physiologic and strength changes in elite male boxers who lost body mass rapidly before the competition.Methods 30 thirty boxers who were aged between 19-24 years and having a mean age of 7.4 years participated in the study. To evaluate the effect of short-term dietary intake interventions on body composition and muscle strength before the competition, boxers were divided into three groups: control (C), exercise+diet1 (E+D1) and exercise+diet2 (E+D2) groups. The dietary habits of the participants were controlled and they participated in the training program. The data of the study consisted of variables such as body mass, height, regional muscle mass, body fat percentage, biceps and femur bicondylar circumference measurements before the competitions. Isometric strength measurements of knee extensors and flexors and shoulder internal and external rotators were also recorded.Results Physiologic parameters such as body mass change, BMI level, body fat percentage and leg muscle ratios of E+D2 were significantly decreased compared to C and E+D1 groups. Furthermore, submaximal and maximal strength production in knee extensors and flexors as well as shoulder internal and external rotators were significantly decreased in E+D2 compared to C and E+D1 groups.Conclusion The tendency to lose body mass quickly in a short of time may give the desired results in terms of BMI, body mass and fat percentage, but it may cause strength losses in boxers during the competition period.
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    Farklı egzersizler uygulanan ratlarda koenzim Q10 takviyesinin serum, kalp kası ve iskelet kaslarinda tümstatin ekpresyonlarına ve lipit profiline etkisi
    (İnönü Üniversitesi, 2021) Yasul, Yavuz; Akçınar, Faruk; Çı?nar, Vedat
    Amaç: Bu çalışma sıçanlara koenzim Q10 (CoQ10) takviyesi ile birlikte uygulanan farklı yoğunluktaki egzersizlerin tümstatin ekpresyon düzeyleri ve sıçan lipit profili üzerine etkisini belirlemek amacıyla yapılmıştır. Materyal ve Metot: Yapılan deneysel çalışmada 42 adet 8 haftalık erişkin Wistar albino ırkı erkek sıçan kullanıldı. Sıçanlar rastgele kontrol, CoQ10 takviye, aerobik ve anaerobik egzersiz, aerobik CoQ10, anaerobik CoQ10 takviye+egzersiz şeklinde 6 gruba ayrıldı. Tüm gruplar (kontrol ve CoQ10 grubu hariç) ilk haftayı koşu bandına ve egzersiz protokolüne hazırlık evresi olarak geçirdi. CoQ10 takviyesi gavaj yöntemi ile verildi. Tüm sıçanlara ait serum örnekleri, iskelet ve kalp kası dokuları -80 ?C'de muhafaza edildi ve tümstatin seviyeleri ELISA yöntemiyle tespit edildi. Histolojik çalışmalar için ise sıçanlardan alınan iskelet ve kalp kası dokuları formaldehitte tespit edildi ve takip serilerinden geçirilerek parafin bloklara gömüldü. Parafin bloklardan mikrotom ile 5-6 µm kalınlığında kesitler alındı ve alınan kesitler immünohistokimya metodu ile boyandı. Boyanan preparatlar araştırma mikroskobunda incelendi ve fotoğraflandı. Bulgular: Çalışmanın sonunda sıçan canlı ağırlıkları, serum HDL, VLDL, trigliserit ve kolesterol seviyeleri gruplar arasında anlamlı düzeyde farklıydı. Yine kalp ve iskelet kası homojenatlarındaki tümstatin seviyelerinde gruplar arasında anlamlı farklılıklar izlendi. Bu farklılıklar immünohistokimya metodu ile boyanan preparatlar tarafından desteklendi. Sonuç: Çalışmada, egzersiz yoğunluğu ve CoQ10 takviyesi lipit profilini önemli düzeyde etkileyerek HDL, VLDL, trigliserit ve kolesterol seviyelerini iyileştirdiği gözlemlendi. Ayrıca egzersiz yoğunluğu ve CoQ10 takviyesi tümstatin salınım düzeyini de etkiledi. Dolayısıyla bu etki kalp ve iskelet kasında anjiyogenezi yeniden modelledi.
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    Investigation of Iris, Leptin, Ghreline and Some Hormonal Responses of the Strength Training Program Applied to Handball Players
    (Lahore Medical Research Center Llp, 2021) Turgut, Mine; Cinar, Fidan; Dundar, Aykut; Yasul, Yavuz; Cinar, Vedat; Yamaner, Yusuf Burak
    Background: The effects of exercise on physiological systems were an inevitable truth. Especially the relationship of exercise with the endocrine system was one of the important focuses of interest. Irisin, Seratonin, Melatonin, Leptin, Ghrelin and Apelin hormones, which become a ball of interest recently, were the subjects that researchers follow and work with great interest. Aim: This study aimed to determine the effect of strength training program applied to handball players on the Irisin, Seratonin, Melatonin, Leptin, Ghrelin and Apelin hormones. Method: 24 healthy male handball players between the ages of 18-24 participated in the study. Participants were randomly divided into two groups (control and experimental). While handball training was applied to the first group (control) for 6 weeks, strength training was applied to the second group (experimental). The blood samples of the participants were taken on an empty stomach in the morning by experts in the appropriate laboratory environment before the training at rest, according to the pre-test and post-test model. In the analysis of the data, descriptive statistics (mean, standard deviation) and Shapiro Wilk test, kurtosis, steepness and histogram graph were taken into consideration to test the normality of the distribution before starting the analysis, and it was observed that the distribution was normal. In this context, Paired Samples t-test was used to reveal intra-group differences and the Independent samples t-test statistical techniques were used to reveal differences between groups. The level of significance was set at 0.05 and the analyses were made in the Windows SPSS 22 package program. Results: It was observed that irisin, apelin and ghrelin levels increased in the experimental group of the strength training program applied with the obtained results, it did not change in the control group. It was determined that the serotonin level increased in both the strength training group and the control group. While it was observed that the leptin level decreased in the Strength group, it did not change in the control group, and it was understood that the melatonin level did not undergo any change in both the experimental and control groups. Conclusion: As a result, it was concluded that the 6-week strength training protocol applied to athletes caused significant changes in irisin, apelin, ghrelin, serotonin, leptin levels of handball players, but did not show any change in melatonin levels.