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    Aripiprazole-induced transient myopia
    (Kare Publ, 2020) Cumurcu, Tongabay; Cumurcu, Birgul Elbozan; Yesil, Bahar; Gunduz, Abuzer
    This study aims to present a case of transient myopia due to aripiprazole used in the treatment of depression. A 21-year-old female who was being treated for depression with 15 mg/day Aripiprazole during two months. She normally used -3.75 D glasses. She was admitted to our outpatient clinic with sudden onset blurring of vision in both eyes despite using glasses for about three days. Using of aripiprazole was observed in the patient's history. She was found to have myopia of -6.0 diopters in both eyes with measurement of otorefractometer; her visual acuity was 6/10 in both eyes with her glasses. The other eye examination findings of the patient were normal. The drug was discontinued, and the patient was followed. One mount later on examination, the patient's visual acuity increased to 10/10 in both eyes. Following the first day of the Alx values measured were 0.3 mm longer than one month after the measurement; the minimal difference between the other anterior segment findings were recorded. Although the specific mechanisms that cause acute myopia has not been fully revealed, it can be ciliary spasm, ciliary bodies effusion, peripheral uveal effusion and effects of ocular serotonergic intraneural fibers. We believe that it would be important for clinicians. They should keep in mind these conditions when prescribing aripiprazole and need to inform patients about the side effects related to the eye.
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    Gabapentin withdrawal in a depressed patient: A case report
    (Cumhuriyet Univ Tip Fak Psikiyatri Anabilim Dali, 2016) Yesil, Bahar; Elbozan, H. Birgul
    The third generation antiepileptic, gabapentin, is a structural analogue of gamma aminobutyric acid (GABA), which is an important neurotransmitter of central nervous system. It is used to treat partial epilepsy, neuropathic pain, and movement disorders, as well as a variety of psychiatric conditions such as bipolar disorder, anxiety disorder, and alcohol addiction. Currently it is accepted to possess a potential for abuse and addiction. In this study, we present a case of a woman with depression who had been using a high dose gabapentin treatment for neuropathic pain due to spinal surgery performed 3 years before. Here, we highlight the withdrawal symptoms following the termination of gabapentin, and their treatment. The symptoms of varying severity in gabapentin withdrawal underline the importance of progressively decreasing the dose on a schedule of several months before ceasing the drug completely. Predisposing factors should be noted, and alternative treatment options like melatonin and mirtazapine should be considered.
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    An investigation on the effects of music training on attention and working memory in adults
    (Cumhurıyet unıv tıp fak psıkıyatrı anabılım dalı, cumhurıyet unıv tıp fak psıkıyatrı abd, sıvas, 58140, turkey, 2017) Yesil, Bahar; Unal, Suheyla
    Objective: Determining the effects of music training on attention and working memory in adult music trainees using neuropsychological tests. Methods: The study was conducted within January-June 2014 at the Music Department of Inonu University. Twenty-two students of age 18-26 were matched one to one in terms of age, gender, level of academic education and dominant hand. Participants with substance abuse, psychiatric and neurological disease were excluded from study. ASRS, Stroop and WMS-R were applied on first and fourth year students. Results: The sample consisted of 24 women and 20 men. The mean age was 22 +/- 1.5 years and the mean academic level of education was 15 +/- 1.5 years. There was no significant difference between first and fourth year students in terms of ASRS-A, ASRS-B and ASRS total scores. There was no significant difference between groups in pre-university music experience. Fourth year students were better at greyscale word reading, color word reading and box color statement in Stroop. There was no significant difference in word color statement. Fourth year students were better in reverse month counting and counting by sevens in WMS-R. No significant difference was found in countdown range, short and long-term verbal and visual recognition, memory, mental control and concentration. Conclusion: Long-term and regular music training did not affect attention shifting in adults significantly, but caused improvement in some tests requiring working memory activity. Irregular music experience did not have significant contribution. Regular and intensive music practice may have functional effects on cognition in adults. (Anatolian Journal of Psychiatry 2017; 18(6): 531-535)