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    Acute pancreatitis: an obscure complication of organophosphate intoxication
    (Sage Publications Ltd, 2003) Harputluoglu, MMM; Kantarceken, B; Karincaoglu, M; Aladag, M; Yildiz, R; Ates, M; Yildirim, B
    Acute pancreatitis secondary to organophosphate intoxication is a rare and generally well-course condition, but it is important to be aware of this complication for appropriate clinical management. There are a few reports about this subject in the literature, but it is believed that there are more cases than are reported for this condition. Because symptoms of toxicity can mask this severe complication, we report two cases of acute pancreatitis due to organophosphate intoxication for alerting this condition.
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    Bilateral transient hearing loss associated with vincristine therapy: Case report
    (E I F T Srl, 2000) Aydogdu, I; Ozturan, O; Kuku, I; Kaya, E; Sevinc, A; Yildiz, R
    Vincristine, adriamycin, and dexamethasone (VAD) chemotherapy protocol is first-choice treatment in newly diagnosed multiple myeloma patients in many centers. Sudden hearing loss associated with vincristine therapy is a rarely observed event in the VAD protocol. We describe a 69-year old male patient diagnosed with multiple myeloma 7 months ago who developed sudden bilateral hearing loss related to vincristine therapy. This uncommon adverse effect of vincristine is discussed and the literature reviewed.
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    Brain natriuretic peptide and severity of disease in non-alcoholic cirrhotic patients
    (Wiley, 2005) Yildiz, R; Yildirim, B; Karincaoglu, M; Harputluoglu, M; Hilmioglu, F
    Background: Cirrhotic patients have a hyperdynamic systemic circulation. They have insidious cardiac problems besides well-known complications. Brain natriuretic peptide (BNP) relaxes vascular smooth muscle and has a portal hypotensive action. The relations between BNP levels and severity of disease, cardiac dysfunction and esophageal varices were studied in non-alcoholic cirrhotic patients. Methods: Fifty-two non-alcoholic cirrhotic patients were evaluated for decompensation component of cirrhosis. The BNP concentration of echocardiographically examined patients was determined. Results: The BNP levels were significantly higher in ascites, spontaneous bacterial peritonitis and hepatic encephalopathy history group (P = 0.033, P < 0.001, P = 0.014, respectively), but no significant difference were observed for presence of esophageal varices and bleeding history (P = 0.267, P = 0.429). A significant correlation was observed between BNP concentration and Child score (r = 0.427, P = 0.012), interventricular septal thickness (r = 0.497, P < 0.001) and left ventricular posterior wall thickness (r = 0.526, P < 0.001). According to Child-Pugh classification there were no significant difference between groups for echocardiographic measurements and blood pressure (P > 0.05), but plasma BNP levels were significantly higher in Child class B and C patients compared with class A patients (P < 0.05). Conclusion: Increased levels of BNP are more likely related to the severity of disease in non-alcoholic cirrhotic patients. The advanced cirrhosis is associated with more advanced cardiac dysfunction and BNP has prognostic value in progression of cirrhosis. (C) 2005 Blackwell Publishing Asia Pty Ltd.
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    Cardiac tamponade as initial presentation of Sheehan's Syndrome
    (Elsevier Ireland Ltd, 2004) Sahin, I; Taskapan, H; Yildiz, R; Kosar, F
    [Abstract Not Available]
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    Effect of obesity on P wave duration and P wave dispersion
    (Nature Publishing Group, 2004) Ari, F; Sabin, I; Kosar, F; Taskapan, H; Gunen, H; Yildiz, R
    [Abstract Not Available]
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    Spontaneous small bowel perforations due to intestinal tuberculosis should not be repaired by simple closure
    (Elsevier Science Inc, 2005) Ara, C; Sogutlu, G; Yildiz, R; Kocak, O; Isik, B; Yilmaz, S; Kirimlioglu, V
    Intestinal tuberculosis is a major problem in marry regions of the world. The incidence of it is rising in Western countries due to immigration from Third World countries and human immunodeficiency virus infection. The difference between the simple closure and resection and anastomosis was evaluated in this study. Retrospectively, 12 patients with intestinal tuberculosis diagnosed histopathologically among 50 patients with free intestinal perforations operated on between 1995 and 2003 at Turgut Ozal Medical Center were evaluated. Each patient underwent routine laboratory tests and radiologic studies. The most common symptoms of patients were abdominal pain, night sweats, and weight loss. Sites of perforation were ileum in 10 patients (multiple perforation in 4) and jejunum in 2 patients (both had multiple perforations). The perforation was closed by primary closure in 7 patients. Resection-anastomosis was performed in 5 patients. Leaks occurred in overall 3 of 7 patients with primary closure. Three of the 7 patients with leaks due to septicemia died. The mortality rate among all patients was 25%. Intestinal tuberculosis should be kept in mind as a cause in free intestinal perforations. Because of high mortality rate, the resection of the affected area and anastomosis may be the treatment of choice rather than primary closure. (c) 2005 The Society for Surgery of the Alimentary Tract.