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Öğe Comparison of extraction methods for measurement of hair cortisol(Wiley, 2017) Atcali, T.; Yildiz, S.; Ucar, C.; Ugras, S.[Abstract Not Available]Öğe Comparison of Methods for Alpha-Amylase Measurement in Saliva(Wiley, 2017) Barutcu, I.; Ozgocer, T.; Cakan, P.; Ucar, C.; Yildiz, S.[Abstract Not Available]Öğe Effect of early tail-docking on luteinizing hormone pulse frequency in fat-tailed Tuj ewe-lambs(Shiraz Univ, 2013) Kaya, M.; Cenesiz, M.; Onder, F.; Uzun, M.; Yildiz, S.The aim of the study was to investigate the effect of tail-docking on the LH pulse frequency in female Tuj lambs. Twelve female lambs were assigned into two equal groups. A rubber ring was applied to the base of the tail for shedding off. Blood samples were collected for 8 h in the 4th and 8th months of age to determine pulsatile secretion of LH. Starting from the age of 6 months, blood samples were taken thrice weekly for progesterone analyses. There was no LH pulse in the first LH analysis but the pulses were observed in both groups in the second LH analysis. However, number of pulses was not different between groups. The plasma progesterone level was less than 1 ng/ml throughout the breeding season. In conclusion, there was no effect of the tail-docking on pulsatility of LH in fat-tailed female lambs.Öğe The effect of maternal nutrition level during the periconception period on fetal muscle development and plasma hormone concentrations in sheep(Cambridge Univ Press, 2016) Sen, U.; Sirin, E.; Yildiz, S.; Aksoy, Y.; Ulutas, Z.; Kuran, M.The effect of maternal nutrition level during the periconception period on the muscle development of fetus and maternal-fetal plasma hormone concentrations in sheep were examined. Estrus was synchronized in 55 Karayaka ewes and were either fed ad libitum (well-fed, WF, n=23) or 0.5xmaintenance (under-fed, UF, n=32) 6 days before and 7 days after mating. Non-pregnant ewes (WF, n=13; UF, n=24) and ewes carrying twins (WF, n=1) and female (WF, n=1; UF, n=3) fetuses were removed from the experiment. The singleton male fetuses from well-fed (n=8) and under-fed (n=5) ewes were collected on day 90 of gestation and placental characteristics, fetal BWs and dimensions, fetal organs and muscles weights were recorded. Maternal (on day 7 after mating) and fetal (on day 90 of pregnancy) blood samples were collected to analyze plasma hormone concentrations. Placental characteristics, BW and dimensions, organs and muscles weights of fetuses were not affected by maternal feed intake during the periconception period. Maternal nutrition level did not affect fiber numbers and the muscle cross-sectional area of the fetal longissimus dorsi (LD), semitendinosus (ST) muscles, but the cross-sectional area of the secondary fibers in the fetal LD and ST muscles from the UF ewes were higher than those from the WF ewes (P<0.05). Also, the ratio of secondary to primary fibers in the ST muscle were tended to be lower in the fetuses from the UF ewes (P=0.07). Maternal nutrition level during the periconception period did not cause any significant changes in fetal plasma insulin and maternal and fetal plasma IGF-I, cortisol, progesterone, free T3 and T4 concentrations. However, maternal cortisol concentrations were lower while insulin concentrations were higher in the WF ewes than those in the UF ewes (P<0.05). These results indicate that the reduced maternal feed intake during the periconception period may alter muscle fiber diameter without affecting fiber types, fetal weights and organ developments and plasma hormone concentrations in the fetus.Öğe Evaluation of estrogenic effects of polychlorinated biphenyls and organochlorinated pesticides using immature rat uterotrophic assay(Sage Publications Ltd, 2013) Uslu, U.; Sandal, S.; Cumbul, A.; Yildiz, S.; Aydin, M.; Yilmaz, B.In this study, we investigated the effects of polychlorinated biphenyls (PCBs) and organochlorinated pesticides on the serum levels of luteinising hormone (LH), follicle stimulating hormone (FSH) and weights and histomorphometry of uterine tissue in immature female rats using uterotrophic assay. A total of 36 rats were randomly divided into six groups (n = 6 per group) as control, oestradiol (E-2, 100 mu g/kg), PCB 180, Aroclor 1221, endosulfan and mirex at 10 mg/kg dosage. After 3 days of injections (subcutaneous), animals were decapitated and blood samples were collected. Uteri were dissected, weighed out and then fixed in 10% formaldehyde. They were processed for histomorphometry. The serum levels of LH and FSH were determined by enzyme immunoassay. Uterine weight was significantly increased by E-2 and reduced by mirex (p < 0.001 and p < 0.05, respectively). Total volume of uterus was significantly raised by E-2, Aroclor 1221 and endosulfan compared with that of the control group (p < 0.01). The ratio of epithelium was significantly increased by E-2, PCBs and pesticides (p < 0.01). The uterine cavity ratio was decreased by aroclor (p < 0.01), PCB 180 and mirex (p < 0.05). The serum levels of LH did not significantly differ among the groups but the levels of FSH were decreased by PCB 180 and endosulfan (p < 0.05 and p < 0.01, respectively). These findings suggest that PCB 180, Aroclor 1221 and endosulfan may be estrogenic in immature uterotrophic assay.Öğe Heart-rate variability did not affect subsequent night sleep parameters and cortisol awakening response(Wiley, 2017) Ucar, C.; Ozgocer, T.; Yildiz, S.[Abstract Not Available]Öğe IL-1beta, IL-6 and TNF-alpha levels in women working in half-or whole-night shifts(Pergamon-Elsevier Science Ltd, 2018) Cakan, P.; Yildiz, S.[Abstract Not Available]Öğe IL-1beta, IL-6 and TNF-alpha levels in women working under long-term (32-36 hour) shifts(Pergamon-Elsevier Science Ltd, 2018) Cakan, P.; Yildiz, S.[Abstract Not Available]Öğe Is amygdala size correlated with stress?(Via Medica, 2021) Canbolat, M.; Erbay, M. F.; Senol, D.; Ucar, C.; Yildiz, S.Background: One of the important mechanisms that regulate the stress response of the body is hypothalamic pituitary adrenal axis. One of the structures activating this axis is amygdala. We have seen people around who react calmer and cooler to very stressful situations. Are people with smaller amygdala really calmer? Or, can we say that the bigger the amygdala, which is the trigger of the body's response to stress, the more a person panics? Aim of the study is to compare the saliva cortisol levels and amygdala volume. Materials and methods: Study conducted with 63 male students. Magnetic resonance images of students were taken before their final exam to calculate amygdala volumes. Saliva samples of all students were taken two times to detect cortisol levels in saliva. First one was 20 days before the final exam and second one was on the exam day. We assumed that the students were stressful on exam day. Results and Conclusions: No statistically significant correlation was found between saliva cortisol levels and amygdala volume in the study.Öğe Late-night eating increased cortisol awakening response but did not affect heart rate variability in the next morning(Wiley, 2017) Ucar, C.; Ozgoceri, T.; Yildiz, S.[Abstract Not Available]Öğe Lengths of the menstrual cycle and menstruation are positively correlated with general tiredness in long-term entrained students(Wiley, 2017) Ugras, S.; Ucar, C.; Atcali, T.; Yildiz, S.[Abstract Not Available]Öğe Long shift hours was associated with increased attention performance in pediatric registrars(Wiley, 2017) Cakan, P.; Yildiz, S.[Abstract Not Available]Öğe Nurses have higher blood leucocyte counts following night-shift works(Wiley, 2017) Cakan, P.; Yildiz, S.[Abstract Not Available]Öğe Sympatho-vagal balance is higher in nurses following night-shift works(Wiley, 2017) Cakan, P.; Ucar, C.; Barutcu, O.; Yildiz, S.[Abstract Not Available]Öğe Thrombocytapheresis decreases systolic blood pressure and increases sympatho-vagal balance(Pergamon-Elsevier Science Ltd, 2018) Cakan, P.; Ozgul, M.; Erkurt, M.; Kaya, E.; Yildiz, S.; Kuku, I.[Abstract Not Available]Öğe Thrombocytapheresis decreases systolic blood pressure and increasessympatho-vagal balance(Pergamon-elsevıer scıence ltd, the boulevard, langford lane, kıdlıngton, oxford ox5 1gb, england, 2018) Cakan, P.; Ozgul, M.; Erkurt, M.; Kaya, E.; Yildiz, S.; Kuku, I.