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  • Küçük Resim
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    Anterior segment parameters and tear functions in patients with thalassemia major
    (2019) Bayramoglu, Sadik Etka; Aydogan, Gonul; Erdogan, Mehmet; Yildiz Ekinci, Dilbade; Sayin, Nihat
    Aim: To determine whether the biomicroscopic, topographic and biomechanical properties of the anterior segment and the tear function have changed in Thalassemia Major (TM) patients.Material and Methods: Eighty-eight eyes of patients with TM and 102 eyes of healthy controls paired with age, gender, and spherical equivalent were included in this cross- sectional case-control study. Biomicroscopic, topographic and biomechanical findings of anterior segment and Schirmer test measurements were compared between the two groups.Results: The mean age was found to be 15.11±6.01years in TM group, and 13.83±4.92 years in the control group (p=0.17). In 34 (38.63%) patients with TM, minor peripheral lens opacities were detected. Visual acuity was 20/20 in all patients with lens opacity. The mean iridocorneal angle (ICA) was 44.67±5.86 and the topographic anterior chamber depth (ACD) was 3.65±0.28 mm in the TM patients. Mean ICA was 48.78 ± 6.51 and topographic ACD was 3.76±0.30 mm in the control group (p0.001 and P=0.02 respectively). The mean Schirmer test result was 14.06±4.13 mm in patients with TM and 16.2±3.75 mm in the control group (p=0.001).Conclusion: In contrast to previous literature, we did not found any vision decreasing complications in the TM group. Although peripheral lenticular opacities were detected in some of the patients with TM, none of the patients had an anterior segment finding that could reduce visual acuity. Intraocular lens calculation formulas and surgical technique may be affected due to decreased ICA and ACD values in patients with TM.
  • Küçük Resim
    Öğe
    Keratoplasty indications and outcomes: The experience of a tertiary health center in Southeastern of Turkey
    (2019) Balsak, Selahattin; Yildiz Ekinci, Dilbade
    Aim: The study aims to report the indications of keratoplasty surgeries and our surgical outcomes performed in our hospital that provides tertiary health care.Materials and Methods: This retrospective study was conducted analyzing the files of the patients undergone keratoplasty for optical, therapeutic and tectonic purposes between 2014-2018. The patients' age, gender, indication for keratoplasty, preoperative and postoperative best-corrected visual acuity and surgical technique preferred, whether graft rejection developed or not during postoperative follow-ups, treatments administered to the patients developed rejection and follow-up periods were recorded.Results: The study included 200 eyes of 174 patients undergone keratoplasty. Of the eyes 180 (90%), 13 (6.5%) and 7 (3.5%) received corneal transplantation for optical purpose, for tectonic/therapeutic purpose and for cosmetic purpose respectively. The mean follow-up period was 21.7±6.2 months (range 6-48 months). Of the eyes 78 (39%), 40 (20%), 25 (12.5%), 19 (9.5%), 16 (8%), 11 (5.5%), and 9 (4.5%) were operated due to infectious/non-infectious corneal scar, pseudophakic/aphakic bullous keratopathy, graft failure/rejection, corneal dystrophy, keratoconus, keratitis/abscess and spontaneous corneal perforation respectively. Forty (20%) of the eyes developed allograft reaction. At the end of the study period, 50 (25%) eyes could not maintain graft transparency. The most common causes of inability to maintain graft transparency were endothelial failure and allograft reaction.Conclusion: Keratoplasty is an important and effective surgical method that increases visual acuity in blindness conditions caused by corneal diseases.Keywords: Cornea; graft survival; keratoplasty.