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    Antibodies to Borna Disease Virus in Children with Attention Deficit-Hyperactivity Disorder Borna disease virus serology in Attention Deficit-Hyperactivity Disorder
    (Universitatsverlag Ulm Gmbh, 2009) Ozcan, Ozlem; Gungor, Serdal; Helps, Chris R.; Turan, Nuri; Tabel, Yilmaz; Saget, Hasan; Yilmaz, Hueseyin
    Borna disease virus (BDV) causes behavioral disorders in rats infected in the newborn period. We investigated BDV serology in children with attention deficit hyperactivity disorder (ADHD). Method: Ninety-nine children with ADHD (mean age: 8.7 +/- 2.5) and 104 control children (mean age: 8.4 +/- 2.8) were included in the study. All sera were investigated using the Enzyme-Linked Immunosorbent Assay (ELISA) method for BDV antibodies. Results: The rate of sero-positivity was 2% (2 of 99) in ADHD and 3.8% (4 of 104) in the control group. There was no significant difference between ADHD and control group for BDV sero-positivity. Conclusion: Our results do not support a role of BDV infections in the pathogenesis of ADHD.