Yazar "Yilmaz, Murat" seçeneğine göre listele

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    Impact of telephonic interviews on persistence and daily adherence to insulin treatment in insulin-naive type 2 diabetes patients: dropout study
    (Dove Medical Press Ltd, 2016) Yavuz, Dilek Gogas; Bilen, Habip; Sancak, Seda; Garip, Tayfun; Hekimsoy, Zeliha; Sahin, Ibrahim; Yilmaz, Murat
    Objective: The objective of this study is to evaluate the impact of sequential telephonic interviews on treatment persistence and daily adherence to insulin injections among insulin-naive type 2 diabetes patients initiated on different insulin regimens in a 3-month period. Methods: A total of 1,456 insulin-naive patients with type 2 diabetes (mean [standard deviation, SD] age: 56.0 [12.0] years, 49.1% were females) initiated on insulin therapy and consecutively randomized to sequential (n=733) and single (n=723) telephonic interview groups were included. Data on insulin treatment and self-reported blood glucose values were obtained via telephone interview. Logistic regression analysis was performed for factors predicting increased likelihood of persistence and skipping an injection. Results: Overall, 76.8% patients (83.2% in sequential vs 70.3% in single interview group, (P<0.001) remained on insulin treatment at the third month. Significantly higher rate for skipping doses was noted in basal bolus than in other regimens (27.0% vs 15.0% for premixed and 15.8% basal insulin, respectively, P<0.0001). Logistic regression analysis revealed sequential telephonic interview (odds ratio [OR], 1.531; 95% confidence interval [CI], 1.093-2.143; P=0.013), higher hemoglobin A1c levels (OR, 1.090; 95% CI, 0.999-1.189; P=0.049), and less negative appraisal of insulin therapy as significant predictors of higher persistence. Basal bolus regimen (OR, 1.583; 95% CI, 1.011-2.479; P=0.045) and higher hemoglobin A1c levels (OR, 1.114; 95% CI, 1.028-1.207; P=0.008) were the significant predictors of increased likelihood of skipping an injection. Conclusion: Our findings revealed positive influence of sequential telephonic interview, although including no intervention in treatment, on achieving better treatment persistence in type 2 diabetes patients initiating insulin.
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    A NEW APPROACH FOR THE PREDICTION OF BRITTLENESS INDEX BASED ON CHEMICAL PROPERTIES OF BASALTIC ROCKS
    (Acad Sci Czech Republic Inst Rock Structure & Mechanics, 2021) Bilen, Candan; Er, Selman; Tugrul, Atiye; Yilmaz, Murat
    Rock brittleness is one of the most important issues in rock mechanics. There is not yet an available method for defining or measuring directly the rock brittleness. The aim of this study is to suggest a new chemical index parameter for the prediction of basaltic rocks' brittleness. In the order of that abovementioned purpose, a total of 23 basaltic rock samples were collected from different region of Turkey. Samples were initially tested to determine their chemical properties. Then, mechanical tests were carried out to define the brittleness indices (B1, B2, and B3) for each corresponding sample. Finally, relations between parameters obtained from test results and brittleness indices were examined with regression analysis. According to the results obtained, a new chemical parameter (CP) was proposed for predicting brittleness via major oxide element components of basaltic rocks. It was found out that, B1 and B2 are not reliable parameters for predicting the different properties, however; B3 and CP can be employed as good criteria for predicting the different properties of basaltic rocks (especially in terms of chemical and mechanical properties).