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    Meteorologic parameters and migraine headache: ED study
    (W B Saunders Co-Elsevier Inc, 2015) Yilmaz, Mustafa; Gurger, Mehtap; Atescelik, Metin; Yildiz, Mustafa; Gurbuz, Sukru
    Aim: Migraine is common in society and is one of the primary causes of chronic headache with episodes. In this study, we aimed to determine the role of meteorologic parameters and moon phase on triggering migraine attacks and effects on the number of patients presenting to the emergency department with migraine headaches. Materials and Methods: Patients admitted to the emergency department due to a migraine headache during a 1-year period were studied retrospectively. Correlation between moon phases, pressure, temperature, humidity, wind speed values of meteorologic observation, and recording station located in the same city and daily number of patients was analyzed. Results: A total of 3491 patients, of whom 72% (n = 2518) were women, were enrolled. The average daily number of patients was 9.6 +/- 4 (3-24). A statistically significant correlation was found between the number of daily patients and daily maximum temperature (P = .005), mean temperature (P = .013), minimum temperature (P = .041), and daily temperature change (P = .003). In addition, a negative correlation was found between the daily number of patients presenting to the emergency department and daily relative humidity (in percentage; P = .031). No significant relationship was found between moon phases and the number of patients. Conclusion: We have determined that the number of patients admitted to the emergency department with migraine headache has increased with high temperature and low humidity and that there is no relationship between the number of patients and moon phases. (C) 2014 Elsevier Inc. All rights reserved.
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    Neuro-ichthyotic Syndromes: A Case Series
    (Medknow Publications & Media Pvt Ltd, 2018) Incecik, Faruk; Herguner, Ozlem M.; Ozbek, Mehmet N.; Gungor, Serdal; Yilmaz, Mustafa; Rizzo, Wiliam B.; Mert, Gulen G.
    Background: The neuro-ichthyotic diseases are clinically and genetically heterogeneous. The purpose of this study was to evaluate the clinical and neuroradiological findings and to analyze mutation in 15 patients with neuro-ichthyotic diseases. Materials and Methods: We retrospectively analyzed the records of 15 patients with the diagnosis of neuro-ichthyotic diseases. Results: Eight female and seven male patients (age range 11 months-52 years) were investigated. There were eight patients with Sjogren-Larsson syndrome (SLS), five patients with multiple sulfatase deficiency (MSD), one patient with Chanarin-Dorfman's syndrome, and one patient with mental retardation, enteropathy, deafness, neuropathy, ichthyosis, and keratodermia (MEDNIK) syndrome. Parental consanguinity was found in all the patients except one. All patients had ichthyosis. Diagnosis was performed with genetic study. Conclusions: Because biochemical and clinical findings are variable, the diagnosis is difficult in most of the cases. Detailed skin and physical examinations are mandatory in these patients. Genetic tests are necessary for accurate diagnosis.