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    A Case of Anaphylaxis to Legumes During Prick to Prick Test
    (Bilimsel Tip Yayinevi, 2016) Yilmaz, Ozlem; Atici, Serkan; Ertoy Karagol, Hacer Ilbilge; Topal, Erdem; Bakirtas, Arzu; Demirsoy, Mehmet Sadik; Turktas, Ipek
    The most common causes of food allergy vary among countries according to the dietary habits and the frequency of consumption of foods. Legumes are important sources of protein that are widely consumed all over the world. The legume family includes lentils, chickpeas, beans, broad beans as well as peanuts and soybeans. Skin prick tests are generally considered safe. However, systemic reactions may develop during skin prick testing, Systemic reactions from skin testing are more frequent with food, drug, latex and venom allergens. Systemic reactions occur more frequently after prick to prick tests that are performed with fresh food than those with standard extracts. This paper reports a case with a history of anaphylaxis to lentils and peas. The patient was found to have type 1 reaction to chick peas, broad beans and green beans although she did not describe a reaction to these legumes in her history. The patient experienced anaphylaxis during skin testing with legumes when multiple tests were performed at the same time. There was no reaction when skin prick tests were performed in more than one session. The patient is noteworthy in this regard and discussed in detail.
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    Four child cases diagnosed with DRESS syndrome
    (Bilimsel Tip Yayinevi, 2015) Karagol, Hacer Ilbilge Ertoy; Yilmaz, Ozlem; Topal, Erdem; Bakirtas, Arzu
    Drug Reaction with Eosinophilia and Systemic Symptoms'' (DRESS) syndrome, is characterized with fewer, extensive mucocutaneous rash, facial oedema, lymphadenopathy, eosinophilia and/or other hematological abnormalities and internal organ involvement that typically emerge following the latent period that varies between 2-6 weeks after the beginning of drug treatment. It is known that this syndrome, which is assessed among severe cutaneous adverse drug reactions, is less common in children than adults. Although many defining adult studies about DRESS syndrome exist, a limited number of studies in which child cases have been evaluated are available. Therefore, we offered four child cases that first of which is correlated with sulfonamide derivate use of antibiotics and the others of which are diagnosed with use of anticonvulsant dependent DRESS syndrome in our clinic. We aimed to discuss DRESS syndrome in children with clinical and laboratory characteristics, diagnosis and treatment of those cases whose ages vary between 7 and 14 years old.
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    Pityriasis Likenoides et Varilioformis Acuta (PLEVA) prediagnosed as mastoscytosis
    (Bilimsel Tip Yayinevi, 2014) Ertoy Karagol, H. Ilbilge; Yilmaz, Ozlem; Gonul, Ipek Isik; Topal, Erdem; Bakirtas, Arzu
    We presented 6 years-old boy who admitted to our clinic with a pre-diagnosis of cutaneous mastocytosis. The child had red-brown colored, diffuse maculopapular eruptions which were more pronounced on his trunk without any pruritus. The other findings on physical examination were normal. We performed punch biopsy from lesions on his skin to reveal the diagnosis. Histopathological examination of biopsy material was consistent with Pityriasis Likenoides et Varilioformis Acuta (PLEVA). He resolved without treatment in the follow-up period. In this report, we examined the clinical symptoms, diagnostic work-up and treatment of PLEVA and discussed the differential diagnosis of PLEVA with mastocytosis.
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    Turkish League Against Rheumatism National Recommendations for the Management of Ankylosing Spondylitis
    (Turkish League Against Rheumatism, 2011) Bodur, Hatice; Sivas, Filiz; Yilmaz, Ozlem; Ozgocmen, Salih; Gunaydin, Rezzan; Kaya, Taciser; Ataman, Sebnem
    Objectives: To develop Turkish League Against Rheumatism (TLAR) National Recommendations for the management of ankylosing spondylitis (AS). Materials and methods: A scientific committee of 25 experts consisting of six rheumatologists and 19 physical medicine and rehabilitation specialists was formed by TLAR. Recommendations were based on the 2006 ASsessment in Ankylosing Spondylitis International Working Group(ASAS)/European League Against Rheumatism (EULAR) recommendations and a systematic review of associated publications between January 2005 and September 2010. A Delphi process was used to develop the recommendations. Twelve major recommendations were constructed for the management of AS. Voting using a numerical rating scale assessed the strength of each recommendation. Results: The 12 recommendations include patient assessment, patient follow-up along with pharmacological and non-pharmacological methods. Some minor additions and changes have been made to the ASAS/EULAR recommendations. All of the recommendations had sufficient strength. Conclusion: National recommendations for the management of AS were developed based on scientific evidence and consensus expert opinion. These recommendations will be updated regularly in accordance with recent developments.