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    Sociodemographic characteristics of patients with demodex brevis and demodex folliculorum infestation and its association with rosacea and behçet’s disease
    (Scientific Publishers of India, 2015) Durmaz S.; Yula E.; Aycan Kaya O.; Aksoy Gokmen A.; Kilinc C.; Atambay M.; Ekiz O.
    Demodex mites are ectoparasites often found in the skin thought to be associated with the development of some skin diseases. Demodex positivity may be affected by several factors. In order to determine the relationship between Demodex infestation and rosacea disease (RD), Behçet’s disease (BD) and various individual parameters such as gender, personal hygiene and skin type. A total of 238 individuals (61 with RD, 46 with BD, and 131 healthy subjects) were investigated for the presence of Demodex folliculorum and D. brevis using the standardized skin surface biopsy technique and a questionnaire. The incidence of Demodex mites in RD patients was significantly higher when compared to the control group (p=0.010 and p=0.001, respectively). However, there was no difference between those with BD and the control group. There was a significant difference between ages of groups, skin types, use of moisturizer, and itching, without taking into account the presence of Demodex among the disease groups (p<0.05). On the other hand, there was no significant difference between disease groups in terms of data of gender, skin care, epilation, and face washing. Our study reveals that the positivity rates of Demodex mites in rosacea patients were significantly higher. Mean ages of groups, skin types, use of moisturizer, and the presence of itching of the ear and face may be associated with higher density of Demodex mites. © 2015, Scientific Publishers of India. All rights reserved.
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    What is the Importance of Demodex folliculorum and D. brevis in the etiology of blepharitis?
    (Turkiye Klinikleri, 2013) Yula E.; Aycan Kaya Ö.M.; Atambay M.; Do?anay S.; Daldal N.; Ayhan Tuzcu E.
    Objective: It was reported that, Demodex folliculorum (DF) and D. brevis (DB) may cause an infestation in healthy subjects and, may be important for some eye problems such as blepharitis, or these parasites can bring the present disease into a more serious condition. In this study, we aimed to determine which demodex species' density increase in patients with blepharitis and whether the demodex density on face differs from healthy subjects. Material and Methods: In the study, the presence of demodex species was analyzed on eyelashes and faces of 96 patients with blepharitis and 197 healthy subjects. Samples taken through standard superficial skin biopsy technique and eyelash epilation were analyzed with the light microscope. Results: The mean age of the patients with blepharitis was 46.90±16.92 (15-89) years, whereas the mean age of control group was 39.54±17.61 (12-84) years. Among eyelash samples of the patients, 78 (81.25%) samples were found DF positive, whereas 25 (26.04%) of them were found DB positive; on the contrary 30 (15.22%) and 7 (3.55%) of the control group was DF and DB positive, respectively. Among the eyelash samples of the patients, the demodex incidence was statistically significantly higher compared to the control group (p<0.001). There was no significant difference in terms of demodex positivities on face. All patients who were demodex positive on the facial area were also found demodex positive for eyelash samples whereas 8 (24.2%) of eyelash samples were Demodex spp positive in the control group (p<0.001). Conclusion: The results of our study underline that the presence of Demodex spp on facial area may be one the important factors in the pathogenesis of blepharitis. In conclusion, we suggest that taking the demodicosis presence into consideration as a worsening factor may help in the management of blepharitis. © 2013 by Türkiye Klinikleri.