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  • Öğe
    Analyses of changes on skin by aging
    (Wıley-blackwell, 111 rıver st, hoboken 07030-5774, nj usa, 2017) Kazanci, A.; Kurus, M.; Atasever, A.
    Background: This study aimed to evaluate the histological changes occurring in rat skin with increasing age, starting from the intrauterine period. Methods: Thirty-two healthy female Sprague-Dawley rats were evaluated in four groups: group 1 - intrauterine day 19, group 2 - postpartum day 21, group 3 - postpartum day 60, and group 4 - postpartum month 19. Skin samples from the back, abdomen, head, and upper and lower limbs were obtained from each subject under anesthesia. Tissue specimens were evaluated statistically and morphologically for the thicknesses of the epidermis, dermis, and basement membrane; the number, height, and width of dermal papillae; and the mast cell and pilosebaceous counts per group. The changes in collagen/elastic fibers and glycosaminoglycans were also assessed. Results: Epidermal thickness was the highest in the intrauterine group; it decreased in the postpartum period and increased again in the aged group. Basal membrane thickness increased steadily with age. The number, height, and width of dermal papillae and dermal thickness increased up to day 60 after birth although these decreased in the aged group. Mast cell count also reached the maximum in the intrauterine group and gradually decreased with age. Pilosebaceous units of the dermis were fewer in intrauterine specimens; they showed an increase during the postpartum period and a decrease in the aged group. Conclusion: Skin specimens obtained from rats showed striking differences between the intrauterine and postpartum groups. Moreover, the postpartum group showed considerable intra-group differences.
  • Öğe
    A comparıson of vıtamın d levels ın patıents wıth acne vulgarıs and healthy ındıvıduals
    (Sprınger london ltd, 236 grays ınn rd, 6th floor, london wc1x 8hl, england, 2017) Sarac, G.; Koca, T. T.; Sener, S.
  • Öğe
    Management of complications of vitamin e injections into the face
    (Wıley, 111 rıver st, hoboken 07030-5774, nj usa, 2018) Sarac, Gulbahar; Kapicioglu, Yelda; Sener, Serpil; Cenk, Hulya; Akatli, Aysenur
  • Öğe
    Clinical practice guidelines for the diagnosis and treatment of cutaneous leishmaniasis in turkey
    (Wıley, 111 rıver st, hoboken 07030-5774, nj usa, 2018) Uzun, Soner; Gurel, Mehmet S.; Durdu, Murat; Akyol, Melih; Karaman, Bilge Fettahlioglu; Aksoy, Mustafa; Aytekin, Sema; Borlu, Murat; Dogan, Esra Inan; Dogramaci, Cigdem Asena
    Background Cutaneous leishmaniasis ( CL) is a vector- born parasitic disease characterized by various skin lesions that cause disfiguration if healed spontaneously. Although CL has been endemic for many years in the southern regions of Turkey, an increasing incidence in nonendemic regions is being observed due to returning travelers and, more recently, due to Syrian refugees. Thus far, a limited number of national guidelines have been proposed, but no common Turkish consensus has emerged. Objectives The aim of this study was to develop diagnostic and therapeutic guidelines for the management of CL in Turkey. Methods This guideline is a consensus text prepared by 18 experienced CL specialists who have been working for many years in areas where the disease is endemic. The Delphi method was used to determine expert group consensus. Initially, a comprehensive list of items about CL was identified, and consensus was built from feedback provided by expert participants from the preceding rounds. Results Evidence- based and expert- based recommendations through diagnostic and therapeutic algorithms according to local availability and conditions are outlined. Conclusion Because CL can mimic many other skin diseases, early diagnosis and early treatment are very important to prevent complications and spread of the disease. The fastest and easiest diagnostic method is the leishmanial smear. The most common treatment is the use of local or systemic pentavalent antimony compounds.
  • Öğe
    A milia en plaque case
    (Cukurova unıv, fac medıcıne, yayın ve dokumentasyon kurulu, balcalı, adana, 01330, turkey, 2018) Cenk, Hülya; Sarac, Gülbahar; Şahin, Nurhan