Bowen's disease: An uncommon presentation
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2004
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info:eu-repo/semantics/openAccess
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Abstract:Amaç:İlk olarak 1912'de Bowen tarafından tanımlanan bowen hastalığı bir intraepidermal yassı hücreli karsinomdur. Olgu: 65 yaşında erkek hasta 5-6 yıldan beri karın cildinde bulunan lezyon ile başvurdu. Bu asemptomatik deri lezyonu aylar içinde ilerlemiş. Değişik merkezlerde yanlış tanı alan ve tedavi edilen lezyonda kısmi bir gerileme olmuş ancak tekrar büyümeye başlamış. Dermatolojik muayenesinde; göbeğin sağ tarafında, 7cm x 7cm boyutlarında, plak şeklindeki izlenen lezyonun iyi sınırlı, eritemli, pigmentli ve değişik büyüklükte papüller yapıların lezyonun periferine ve merkezine yerleşmiş olduğu izlendi. Histopatolojik muayenesinde; epidermiste kalınlaşma, bazal tabakanın sağlam olduğu, keratinositlerde polarite kaybı ile atipi izlendi. Bowen hastalığı tanısı alan lezyon cerrahi olarak çıkarıldı ve deri grefti konuldu. Sonuç: Nadir yerleşimli Bowen hastalığı olgusunu ilgili kaynakların ışığında tartışarak sunmayı amaçladık.
Abstract:Objective: Bowen's disease described by bowen originally in 1912 is an intradermal squamous cell carcinoma. We aimed to discuss a case of bowen's disease with uncommon presentation in the light of recent literature. Observation a 65-year-old male presented with a lesion over the skin of the abdomen for 5-6 years duration. The lesion gradually enlarged over the years and was asymptomatic. It had been treated and misdiagnosed by different centers, which had resulted in partial regression; however, it started to enlarge again. Dermatologic examination revealed a plaque, 7cmX7cm in size, on the right side of the umbilicus. It was well defined, and erythematous, pigmented, with firm papules of various sizes at the periphery and center of the lesion. Histopathology showed that the lesion was extending through the whole thickness of the epidermis. The basement membrane zone was intact. Keratinocytes showed a loss of polarity and atypia. A diagnosis of "bowen's disease" was made, the lesion was surgically excised, and skin grafting was performed. Conclusion: Bowen's disease should be considered when a skin lesion not responded to treatment or lesion mimics papulosquamous disorders.
Abstract:Objective: Bowen's disease described by bowen originally in 1912 is an intradermal squamous cell carcinoma. We aimed to discuss a case of bowen's disease with uncommon presentation in the light of recent literature. Observation a 65-year-old male presented with a lesion over the skin of the abdomen for 5-6 years duration. The lesion gradually enlarged over the years and was asymptomatic. It had been treated and misdiagnosed by different centers, which had resulted in partial regression; however, it started to enlarge again. Dermatologic examination revealed a plaque, 7cmX7cm in size, on the right side of the umbilicus. It was well defined, and erythematous, pigmented, with firm papules of various sizes at the periphery and center of the lesion. Histopathology showed that the lesion was extending through the whole thickness of the epidermis. The basement membrane zone was intact. Keratinocytes showed a loss of polarity and atypia. A diagnosis of "bowen's disease" was made, the lesion was surgically excised, and skin grafting was performed. Conclusion: Bowen's disease should be considered when a skin lesion not responded to treatment or lesion mimics papulosquamous disorders.
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İnönü Üniversitesi Tıp Fakültesi Dergisi
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KILINÇ N,PINAR Z. Ö (2004). Bowen's disease: An uncommon presentation. İnönü Üniversitesi Tıp Fakültesi Dergisi, 11(2), 93 - 95.
