Allergic Bronchopulmonary Aspergillosis in Patients with Moderate and Severe Asthma

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dc.authorid/0000-0002-7520-760X
dc.authoridAytemur, Zeynep Ayfer/0000-0003-0421-907X
dc.authorwosid/AGG-5502-2022
dc.authorwosidAytemur, Zeynep Ayfer/ABI-7452-2020
dc.contributor.authorAydogan, Oznur
dc.contributor.authorErdinc, Munevver
dc.contributor.authorAytemur, Zeynep Ayfer
dc.contributor.authorSin, Aytul
dc.contributor.authorSavas, Recep
dc.date.accessioned2024-08-04T20:56:27Z
dc.date.available2024-08-04T20:56:27Z
dc.date.issued2008
dc.departmentİnönü Üniversitesien_US
dc.description.abstractIntroduction: Allergic bronchopulmonary aspergillosis (ABPA), which is predominantly a disease of severe asthmatic patients, is caused by hypersensitivity to aspergillus antigens. The prevalence of ABPA is speculative, as the few studies that were performed adopted widely different diagnostic criteria. Material and Method: In this study, we aimed to evaluate the prevalence of ABPA in patients with moderate and severe asthma. ABPA-Central bronchiectasis (ABPA-SB) was diagnosed if a patient had asthma, central bronchiectasis, positive Aspergillus fumigatus skin test or positive serum aspergillus sIgE. ABPASeropositive (ABPA-S) was diagnosed if a patient had asthma, elevated total IgE level, positive Aspergillus fumigatus skin test and positive serum aspergillus sIgE. Results: Of the sixty four patients, 71.9% had moderate asthma and 28.2% severe asthma. Positive Aspergillus sIgE was present in 2 patients (3.1%). Sensitivity to A. fumigatus with skin test was shown in a total of 4 (7.8%) patients. Central bronchiectasis was seen on HRCT in seven of the patients (14.6%) and central mucus impaction was seen in one patient (2%). In this study, ABPA was diagnosed in 2 (3.1%) patients. Two (3.1%) patients were evaluated as aspergillus-sensitive asthma. Conclusion: Patients with ABPA had severe asthma. Therefore, ABPA should be considered in patients with poorly controlled severe asthma.en_US
dc.identifier.endpage156en_US
dc.identifier.issn2149-2530
dc.identifier.issue4en_US
dc.identifier.startpage151en_US
dc.identifier.urihttps://hdl.handle.net/11616/102298
dc.identifier.volume9en_US
dc.identifier.wosWOS:000421652300004en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isotren_US
dc.publisherAvesen_US
dc.relation.ispartofTurkish Thoracic Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectModerate asthmaen_US
dc.subjectsevere asthmaen_US
dc.subjectABPAen_US
dc.titleAllergic Bronchopulmonary Aspergillosis in Patients with Moderate and Severe Asthmaen_US
dc.typeArticleen_US

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