The Republican People's Party and İsmet İnönü at the Transition Into the Multiparty System at the End of Second World War
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Tarih
2008
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info:eu-repo/semantics/openAccess
Özet
Abstract:Amaç: Akut viral hepatit A (HA) ve B (HB) kötü hijyen koşullarının olduğu gelişmekte olan ülkelerde halen yaygın bir sağlık sorunudur. Çeşitli organ ve sistemleri tutan ekstrahepatik anormallikler de bu infeksiyona eşlik edebilir. İnfeksiyonun seyri sırasında kemik iliği hipoplazisi ve bazen de aplazi görülebilir. Bizde HA ve HB tanısı alan olgularda hematolojik anormalliklerin görülme oranlarını belirlemek istedik. Materyal ve Yöntem: HA (Grup 1: 219 olgu) ve HB (Grup 2: 103 olgu) tanısı ile yatırılarak izlenen toplam 322 olgunun başvuru değerleri retrospektif olarak incelendi. HA tanısı anti-HAV IgM yanıtı pozitifliği ve HB tanısı ise artmış karaciğer fonksiyon testleri, HbsAg (+) ve HBeAg (+)’liği ile konuldu. Bulgular: Ortalama lökosit sayısı (8.405±2.682/mm3), nötrofil sayısı (3.985±1.880/mm3), hemoglobin değeri (12.7±1.4g/dl) ve trombosit sayısı (339.149±123.578/mm3) olarak saptandı. Toplam hematolojik anormalliklerin oranı %59.32 (HA %58, HB %61.6) iken lökopeni (%0.93), lökositoz (%20.81), nötropeni (%6.21), anemi (%15.52), trombositopeni (%4.35) ve trombositoz (%11.49) olarak saptandı. Pansitopeni gelişen olgu saptanmadı. Sonuç: Ülkemizde halen önemli bir halk sağlığı sorunu olan HA ve HB olgularının yaklaşık yarısında hematolojik komplikasyon görülmektedir. HA ve HB’de görülen hematolojik anormallik oranları benzerdir.
Abstract:Aim: Acute viral hepatitis A (HA) and B (HB) are currently widespread health problems in developing countries, where poor hygienic conditions are prevalent. Extrahepatic abnormalities which involve many organs and systems can accompany these infections. Therefore we wanted to determine the rate of hematological complications in our cases diagnosed as HA and HB. Material and Methods: Referral test results of a total of 322 cases hospitalized and monitored with diagnoses of HA (Group 1: 219 cases) and HB (Group 2: 103 cases) were analysed retrospectively. Diagnosis of HA was established by Anti-HAV IgM antibody positivity and diagnosis of HB by elevated liver function tests, HbsAg and HBeAg positivity. Results: Mean leukocyte (8.405±2.682/mm3), neutrophil (3.985±1.880/mm3), hemoglobin levels (12.7±1.4 g/dl) and platelet counts (339.149± 123.578/mm3) were determined. The total rate of hematologcal abnormalities was 59.32 % (HA 58 %, HB 61.6 %), while the rates of leukopenia (0.93 %), leukocytosis (20.81 %), neutropenia (6.21 %), anemia (15.52 %), thrombocytopenis (4.35 %) and thrombocytosis (11.49 %) were also assessed. No cases of pancytopenia was detected. Conclusion: Hematological abnormalities were seen in nearly half of the cases with HA and HB, which constitute important public health problems in our country. The rates of hematological abnormalities were similar in HA and HB.
Abstract:Aim: Acute viral hepatitis A (HA) and B (HB) are currently widespread health problems in developing countries, where poor hygienic conditions are prevalent. Extrahepatic abnormalities which involve many organs and systems can accompany these infections. Therefore we wanted to determine the rate of hematological complications in our cases diagnosed as HA and HB. Material and Methods: Referral test results of a total of 322 cases hospitalized and monitored with diagnoses of HA (Group 1: 219 cases) and HB (Group 2: 103 cases) were analysed retrospectively. Diagnosis of HA was established by Anti-HAV IgM antibody positivity and diagnosis of HB by elevated liver function tests, HbsAg and HBeAg positivity. Results: Mean leukocyte (8.405±2.682/mm3), neutrophil (3.985±1.880/mm3), hemoglobin levels (12.7±1.4 g/dl) and platelet counts (339.149± 123.578/mm3) were determined. The total rate of hematologcal abnormalities was 59.32 % (HA 58 %, HB 61.6 %), while the rates of leukopenia (0.93 %), leukocytosis (20.81 %), neutropenia (6.21 %), anemia (15.52 %), thrombocytopenis (4.35 %) and thrombocytosis (11.49 %) were also assessed. No cases of pancytopenia was detected. Conclusion: Hematological abnormalities were seen in nearly half of the cases with HA and HB, which constitute important public health problems in our country. The rates of hematological abnormalities were similar in HA and HB.
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Çocuk Enfeksiyon Dergisi
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AKARSU S,ERENSOY A,ELKIRAN Ö,KURT A,KURT A. Ç,AYGÜN A. D (2008). Hematological abnormalities in patients with acute viral hepatitis A and B. Çocuk Enfeksiyon Dergisi, 2(3), 90 - 95.
