An outbreak associated with multidrug-resistant pseudomonas aeruginosa contamination ofduodenoscopes and an automated endoscope reprocessor

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dc.contributor.authorYetkin, Funda
dc.contributor.authorErsoy, Yasemin
dc.contributor.authorKuzucu, Cigdem
dc.contributor.authorOtlu, Baris
dc.contributor.authorParmaksiz, Nalan
dc.contributor.authorSeckin, Yuksel
dc.date.accessioned2019-07-29T11:01:34Z
dc.date.available2019-07-29T11:01:34Z
dc.date.issued2017
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground: Duodenoscopes are semi-critical devices used for endoscopic retrograde cholangiopancreatography (ERCP). Disinfection of these instruments is usually based on high-level disinfection procedures with a manual or automated endoscope reprocessor (AER). Duodenoscopes and AER are reported very rarely as a source of infection and outbreaks. Aim: To investigate an outbreak caused by Pseudomonas aeruginosa in a Gastroenterology Department and ERCP unit in a university hospital and its underlying risk factors. Method: Three patients in the gastroenterology unit were diagnosed as infected by multidrug-resistant P. aeruginosa and a case control study was conducted for detection of the risk factors. Our infection control team commenced active epidemiological surveillance to determine the cause of these infections. Clonal relationship of the strains was investigated by pulsed field gel electrophoresis (PFGE). Results: Eight patients were affected in the gastroenterology unit during the period November 2007-February 2008. The case-control analysis confirmed that undergoing ERCP was significantly associated with isolation of P. aeruginosa (P=0.0001) in this unit. Six patients' isolates and seven environmental isolates had an indistinguishable PFGE profile, confirming cross-transmission. The healthcare worker implemented infection control measures to resolve the outbreak and no further cases occurred. Conclusions: This outbreak resulted from failure of AER and inadequate high level disinfection procedures. AERs can cause contamination of duodenoscopes and can be related P. aeruginosa outbreaks. Reuse of ancillary materials of ERCP play a critical role in outbreak development.en_US
dc.identifier.citationYetkin, F. Ersoy, Y. Kuzucu, C . Otlu, B. Parmaksiz, N . Seckin, Y. (2017). An outbreak associated with multidrug-resistant pseudomonas aeruginosa contamination ofduodenoscopes and an automated endoscope reprocessor.Cilt:28. Sayı:13. 6064-6070 ss.en_US
dc.identifier.endpage6070en_US
dc.identifier.issue13en_US
dc.identifier.startpage6064en_US
dc.identifier.urihttps://hdl.handle.net/11616/13041
dc.identifier.volume28en_US
dc.language.isoenen_US
dc.publisherAllıed acad, 40 bloomsbury way, lower ground flr, london, wc1a 2se, englanden_US
dc.relation.ispartofBıomedıcal research-ındıaen_US
dc.rightsinfo:eu-repo/semantics/restrictedAccessen_US
dc.subjectFıeld gel-electrophoresısen_US
dc.subjectıntensıve-care-unıten_US
dc.subjectretrograde cholangıopancreatographyen_US
dc.subjectacınetobacter-baumannııen_US
dc.subjectnosocomıal ınfectıonsen_US
dc.subjectrısk-factorsen_US
dc.subjectwasheren_US
dc.subjectbronchoscopesen_US
dc.titleAn outbreak associated with multidrug-resistant pseudomonas aeruginosa contamination ofduodenoscopes and an automated endoscope reprocessoren_US
dc.typeArticleen_US

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