Futility versus acceptability of the use of grafts taken from end of line in the national organ sharing network
Yükleniyor...
Dosyalar
Tarih
2015
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Transplantation Proceedings
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Background. The number of suitable donors for organ transplantation is limited in many
countries. This limitation can be overcome with the use of organs removed from marginal
donors (expanded-criteria donors [ECDs]). We examined the long-term results of 187
patients who underwent marginal cadaveric liver transplantation in our institution.
Methods. The data of patients who underwent cadaveric liver transplantation from
January 2007 to April 2014 were retrospectively reviewed. ECDs were evaluated by
considering 19 internationally accepted criteria. The clinical data of recipients including
age, clinical status, and Model for End-Stage Liver Disease (MELD) score were also
assessed.
Results. A total of 287 patients underwent cadaveric liver transplantation. A graft from
an ECD was used in 181 (63.06%) patients. The mean MELD score was 18.8. In all, 45
patients (24.86%) underwent transplantations for fulminant liver failure and 136 patients
(75.14%) underwent transplantations for other chronic conditions. The majority of donors
died of cerebrovascular disease and trauma. Only hypotension requiring inotropic drugs
and obesity significantly affected survival. The 90-day and 12-month survival rates of the
recipients who received a graft from an ECD were 51.93% and 46.2%, respectively.
Conclusions. The use of ECD allografts immediately and significantly expands the existing
donor pool. Because of persistent organ scarcity, pressure to use a greater proportion of the
existing donor pool will continue to increase.
Açıklama
Transplantation Proceedings, 47, 1257e1261 (2015)
Anahtar Kelimeler
Kaynak
Transplantation Proceedings
WoS Q Değeri
Scopus Q Değeri
Cilt
45
Sayı
7
Künye
Soyer, V., Koç, S., Onur, A., SARICI, K. B., KAYAALP, C., IŞIK, B., … YILMAZ, S. (2015). Futility Versus Acceptability of the Use of Grafts Taken From End of Line in the National Organ Sharing Network. Transplantation Proceedings, 47(5), 1257–1261.
