Single center analysis of the first 304 living donor liver transplantations in 3 years

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Tarih

2013

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Hepatogastroenterology

Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

BACKGROUND/AIMS: Living donor liver transplantations (LDLT) is a definitive treatment for patients with end-stage liver disease (ESLD), especially in the countries with donation problem. Between April 2007 and April 2010, we performed LDLT in 289 patients. Fifteen of the cases required re-transplantations. This study evaluates these 304 consecutive LDLTs donor and recipient outcomes. METHODOLOGY: Complication rates and survival data of the recipients and donors of 304 LDLT cases were analyzed. RESULTS: All donors are alive and well. Overall complication rate was 27%. Early postoperative recipient complication rate was 51%. Most frequent complication was infection. In the long-term there were 57 biliary stricture and 5 chronic bile fistula cases. Chronic and acute rejection attacks developed in 7 and 103 patients, respectively. Hepatic artery thrombosis rate was 8%. One, two and three year survival rates were 82%, 79% and 75%, respectively. Recipient mortality was 25%, mostly due to vascular complications, septic complications, liver dysfunction and chronic rejection. CONCLUSIONS: More than 150 liver tranplantations per year in a single center is a challenge in Turkey, where there is a shortage of deceased donor grafts. LDLT is a safe procedure for donors and effective for ESLD. Improvement in surgical technique would provide better outcomes.

Açıklama

Hepatogastroenterology. 2013 Jul-Aug;60(125):1105-9.

Anahtar Kelimeler

Kaynak

Hepatogastroenterology

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0

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0

Künye

Yılmaz, S., Kayaalp, C., Ara, C., Yılmaz, M., Işık, B., Aydın, C., … Ateş, M. (2013). Single Center Analysis Of The First 304 Living Donor Liver Transplantations İn 3 Years. Hepatogastroenterology, 0–0.