Two possible cases of Trichosporon infections in bone-marrow-transplanted children

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dc.authoridOTLU, BARIS/0000-0002-6220-0521
dc.authoridDURMAZ, RIZA/0000-0001-6561-778X
dc.authorwosidDURMAZ, Rıza/HJH-4918-2023
dc.authorwosidOTLU, BARIS/ABI-5532-2020
dc.authorwosidYALMAN, NEVİN/AAD-6122-2020
dc.contributor.authorAgirbashi, Handan
dc.contributor.authorBilgen, Hulya
dc.contributor.authorOezcan, Sema Keceli
dc.contributor.authorOtlu, Baris
dc.contributor.authorSinik, Gulce
dc.contributor.authorCerikcioglu, Nilguen
dc.contributor.authorDurmaz, Riza
dc.date.accessioned2024-08-04T21:02:18Z
dc.date.available2024-08-04T21:02:18Z
dc.date.issued2008
dc.departmentİnönü Üniversitesien_US
dc.description.abstractTrichosporon spp. are emerging as opportunistic agents that cause systemic diseases in immuno-compromised hosts. Trichosporonosis carries a poor prognosis in neutropenic patients. Trichosporon japonicum was isolated from the air and named by Sugita et al. Here we present the first case of T. japonicum isolated from a clinical specimen. Two cases of acute myeloid leukemia who had Trichosporon isolates are discussed because of their rarity and growing importance. T. asahii was isolated from the throat, feces and urine of the first patient. T. japonicum was isolated from the sputum of the second patient. Both cases produced high MICs to itraconazole, and low MICs to fluconazole and voriconazole. In virulance factor investigations there was (++) biofilm formation in T. japonicum but not in T. asahii. Conventional mycological studies were not adequate for the identification of the isolate at the species level. In our second case as in the first one, the isolate was identified as T. asahii with 99.9% accuracy by API20C AUX. Although two T. asahii isolates from the same patient yielded identical typing profiles by arbitrary primed-PCR, the isolates of the two different patients showed different arbitrary primed-PCR typing profiles. However, the genetic identification of the other patient's strain gave the result of T. japonicum.en_US
dc.identifier.endpage132en_US
dc.identifier.issn1344-6304
dc.identifier.issn1884-2836
dc.identifier.issue2en_US
dc.identifier.pmid18362402en_US
dc.identifier.startpage130en_US
dc.identifier.urihttps://hdl.handle.net/11616/104662
dc.identifier.volume61en_US
dc.identifier.wosWOS:000254711300009en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherNatl Inst Infectious Diseasesen_US
dc.relation.ispartofJapanese Journal of Infectious Diseasesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAsahii Infectionen_US
dc.subjectVoriconazoleen_US
dc.subjectLeukemiaen_US
dc.subjectPatienten_US
dc.subjectBlooden_US
dc.titleTwo possible cases of Trichosporon infections in bone-marrow-transplanted childrenen_US
dc.typeArticleen_US

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