Altered cardiac autonomic function after recovery from COVID-19

dc.authoridAFSIN, ABDULMECIT/0000-0001-9301-9525
dc.authorwosidKutlusoy, Ergun/A-7010-2016
dc.contributor.authorKurtoglu, Ertugrul
dc.contributor.authorAfsin, Abdulmecit
dc.contributor.authorAktas, Ibrahim
dc.contributor.authorAkturk, Erdal
dc.contributor.authorKutlusoy, Ergun
dc.contributor.authorCagasar, Ozlem
dc.date.accessioned2024-08-04T20:56:27Z
dc.date.available2024-08-04T20:56:27Z
dc.date.issued2022
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground Autonomic dysfunction may occur during the acute phase of COVID-19. Heart rate variability (HRV) is a useful tool for the assessment of cardiac sympathetic and parasympathetic balance. We aimed to evaluate cardiac autonomic function by using HRV in subjects after recovery from COVID-19 who had previously symptomatic and were followed outpatiently. Methods The study group composed of 50 subjects with a confirmed history of COVID-19 and the control group composed of 50 healthy subjects without a history of COVID-19 and vaccination. All the study participants underwent 2-dimensional, pulsed- and tissue-Doppler echocardiographic examinations and 24-hour Holter monitoring for HRV analysis. Results Time domain parameters of SDNN, SDANN, SDNNi, RMSSD, pNN50, and HRV triangular index were all decreased in the study group when compared with the control group. Frequency domain parameters of TP, VLF, LF, HF, and HFnu were also decreased in the study group in comparison with the control group. LFnu was similar between groups. Nonlinear parameters of HRV including alpha(1) and alpha(2) decreased in the study group. By contrast, Lmax, Lmean, DET, REC, and Shannon entropy increased in the study population. Approximate and sample entropies also enhanced in the study group. Conclusions The present study showed that all three domain HRV significantly altered in patients after recovery from COVID-19 indicating some degree of dysfunction in cardiac autonomic nervous system. HRV may be a useful tool for the detection of preclinical autonomic dysfunction in this group of patients.en_US
dc.identifier.doi10.1111/anec.12916
dc.identifier.issn1082-720X
dc.identifier.issn1542-474X
dc.identifier.issue1en_US
dc.identifier.pmid34817120en_US
dc.identifier.urihttps://doi.org/10.1111/anec.12916
dc.identifier.urihttps://hdl.handle.net/11616/102301
dc.identifier.volume27en_US
dc.identifier.wosWOS:000721816000001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofAnnals of Noninvasive Electrocardiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectheart rate variabilityen_US
dc.subjectHolteren_US
dc.subjectevent recordersen_US
dc.titleAltered cardiac autonomic function after recovery from COVID-19en_US
dc.typeArticleen_US

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