Effectiveness of intravenous ephedrine infusion during spinal anaesthesia for Caesarean section based on maternal hypotension, neonatal acid-base status and lactate levels

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dc.authoridToprak, Hüseyin İlksen/0000-0001-9293-8116
dc.authorwosidToprak, Hüseyin İlksen/AAN-4023-2020
dc.contributor.authorTurkoz, A
dc.contributor.authorTogal, T
dc.contributor.authorGokdeniz, R
dc.contributor.authorToprak, HI
dc.contributor.authorErsoy, O
dc.date.accessioned2024-08-04T20:58:31Z
dc.date.available2024-08-04T20:58:31Z
dc.date.issued2002
dc.departmentİnönü Üniversitesien_US
dc.description.abstractMaternal cardiovascular changes and neonatal acid-base status, including lactate levels, were assessed in 30 healthy women undergoing elective caesarean section under spinal anaesthesia. Patients were allocated randomly to receive IV ephedrine infusion (n = 15) (5 mg.min(-1)) immediately after the spinal injection or bolus administration of IV ephedrine (n = 15) (10 mg) in case of development of hypotension. Maternal and neonatal blood pressure, heart rate and acid-base status including lactate levels were compared between the groups. Systolic blood pressure in the bolus group was significantly lower when compared to the infusion group. Nausea was observed in one patient (6%) in the infusion group and nausea and vomiting were observed in 10 patients (66%) in the bolus group. Although umbilical arterial pH values were significantly lower in the bolus group, lactate levels were similar. In conclusion, ephedrine infusion prevented maternal hypotension, reduced the incidence of nausea and vomiting and led to improved umbilical blood pH during spinal anaesthesia for caesarean section.en_US
dc.identifier.doi10.1177/0310057X0203000308
dc.identifier.endpage320en_US
dc.identifier.issn0310-057X
dc.identifier.issue3en_US
dc.identifier.pmid12075638en_US
dc.identifier.startpage316en_US
dc.identifier.urihttps://doi.org/10.1177/0310057X0203000308
dc.identifier.urihttps://hdl.handle.net/11616/102924
dc.identifier.volume30en_US
dc.identifier.wosWOS:000176070400008en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherAustralian Soc Anaesthetistsen_US
dc.relation.ispartofAnaesthesia and Intensive Careen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectanaesthesiaen_US
dc.subjectregional : spinal, hypotension, ephedrineen_US
dc.titleEffectiveness of intravenous ephedrine infusion during spinal anaesthesia for Caesarean section based on maternal hypotension, neonatal acid-base status and lactate levelsen_US
dc.typeArticleen_US

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