The effect of caffeic acid phenethyl ester on bacterial translocation and intestinal damage in cholestatic rats
| dc.contributor.author | Ara, Cengiz | |
| dc.contributor.author | Eşrefoğlu, Mukaddes | |
| dc.contributor.author | Polat, Alaadin | |
| dc.contributor.author | Işık, Burak | |
| dc.contributor.author | Aladağ, Murat | |
| dc.contributor.author | Gül, Mehmet | |
| dc.contributor.author | Ay, Selma | |
| dc.contributor.author | Tekerekoğlu, M.Sait | |
| dc.contributor.author | Yılmaz, Sezai | |
| dc.date.accessioned | 2018-02-09T11:51:53Z | |
| dc.date.available | 2018-02-09T11:51:53Z | |
| dc.date.issued | 2006 | |
| dc.department | İnönü Üniversitesi | en_US |
| dc.description | Dig Dis Sci (2006) 51:1754–1760. | en_US |
| dc.description.abstract | We investigated the effect of caffeic acid phenethyl ester in rat ileum injury induced by chronic biliary obstruction. Swiss albino rats were divided into three groups: Group 1, sham (n = 7); Group 2, common bile duct ligation (n = 7); and Group 3, common bile duct ligation plus caffeic acid phenethyl ester (n = 7). In the caffeic acid phenethyl ester-treated rats, ileum tissue levels of malondialdehyde and myeloperoxidase were significantly lower than those of the bile duct-ligated rats (P < 0.001). The levels of tumor necrosis factor-α, interleukin-6, and interleukin-1α in the caffeic acid phenethyl ester group were significantly lower than those in the bile duct ligation group (P < 0.03, P < 0.01, and P < 0.02 respectively). The present study demonstrates that intraperitoneal administration of caffeic acid phenethyl ester in bile duct-ligated rats reduces intestinal oxidative stress. This effect may be useful in the preservation of intestinal damage in cholestasis. | en_US |
| dc.identifier.citation | Ara, C., Eşrefoğlu, M., Polat, A., Işık, B., Aladağ, M., Gül, M., … Tekerekoğlu, M. S. (2006). The Effect Of Caffeic Acid Phenethyl Ester On Bacterial Translocation And İntestinal Damage İn Cholestatic Rats. Dig Dis Sci, 0–0. | en_US |
| dc.identifier.endpage | 1760 | en_US |
| dc.identifier.issue | 0 | en_US |
| dc.identifier.startpage | 1754 | en_US |
| dc.identifier.uri | https://link.springer.com/content/pdf/10.1007%2Fs10620-006-9130-4.pdf | |
| dc.identifier.uri | https://hdl.handle.net/11616/8067 | |
| dc.identifier.volume | 51 | en_US |
| dc.language.iso | en | en_US |
| dc.publisher | Dig Dis Sci (2006) 51:1754–1760 | en_US |
| dc.relation.ispartof | Dig Dis Sci (2006) 51:1754–1760 | en_US |
| dc.rights | info:eu-repo/semantics/openAccess | en_US |
| dc.title | The effect of caffeic acid phenethyl ester on bacterial translocation and intestinal damage in cholestatic rats | en_US |
| dc.type | Article | en_US |
