Etiological evaluation and the role of plasma exchange treatment in trombotic microangiopathies: A retrospective analysis from Eastern Anatolia

dc.contributor.authorHidayet, Emine
dc.contributor.authorErkurt, Mehmet Ali
dc.contributor.authorSarici, Ahmet
dc.contributor.authorBicim, Soykan
dc.contributor.authorBerber, Ilhami
dc.contributor.authorKuku, Irfan
dc.contributor.authorKaya, Emin
dc.contributor.authorKaya, Ahmet
dc.contributor.authorÖzgül, Mustafa
dc.date.accessioned2022-12-27T09:40:58Z
dc.date.available2022-12-27T09:40:58Z
dc.date.issued2022
dc.departmentİnönü Üniversitesien_US
dc.description.abstractThe aim is this study was to make the etiological classification of patients diagnosed with TMA in our region and to statistically evaluate the effect of therapeutic plasma exchange, which we use in treatment, on laboratory recovery and mortality. In our study, between 2009-2017, 85 patients diagnosed with TMA in our center evaluated retrospectively. Thirty- one (36.5%) of our patients were followed up with HELLP, 23 with thrombotic thrombocytopenic purpura (TTP) (27.1%), 20 (23.5%) snake bites, and 11 (12.9%) with atypical hemolytic uremic syndrome (aHUS). TPE treatment was performed in all patients. TPE treatment was found effective in patients with HELLP syndrome, TTP and snake bite and statistically significant improvement was obtained in laboratory parameters (p<0.05). However, TPE treatment was not found to be effective in the treatment of atipical HUS (p>0.05). Mortality rates were found 9.7%, 21.7%, 27.3%, and 0% in patients with HELLP Syndrome, TTP, aHUS, and snake bite, respectively. The primary treatment in HELLP syndrome was termination of pregnancy, it was observed in our study that TPE was effective in TTP, HELLP syndrome and snake bites and treatment should be started without delayen_US
dc.identifier.citationHİDAYET E, ERKURT M, SARICI A, BİÇİM S, KUKU İ, BERBER İ, KAYA E, KAYA A, OZGUL M, UYSAL A (2022). Etiological evaluation and the role of plasma exchange treatment in trombotic microangiopathies: A retrospective analysis from Eastern Anatolia. Medicine Science, 11(2), 762 - 765. 10.5455/medscience.2021.11.379en_US
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/529831/etiological-evaluation-and-the-role-of-plasma-exchange-treatment-in-trombotic-microangiopathies-a-retrospective-analysis-from-eastern-anatolia
dc.identifier.urihttps://hdl.handle.net/11616/85927
dc.language.isoenen_US
dc.relation.ispartofMedicine Scienceen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleEtiological evaluation and the role of plasma exchange treatment in trombotic microangiopathies: A retrospective analysis from Eastern Anatoliaen_US
dc.typeArticleen_US

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