The Humoral Immun Response of Mice to Liposomes Containing Brucella melitensis Outer Membrane Fragments

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dc.authoriddegim, ismail tuncer/0000-0002-9329-4698
dc.authoridGüneş, Gülsen/0000-0003-2021-7103
dc.authoriddegim, ismail tuncer/0000-0002-9329-4698;
dc.authorwosiddegim, ismail tuncer/ADN-3722-2022
dc.authorwosidGüneş, Gülsen/ABG-9068-2020
dc.authorwosidONURDAG, Fatma KAYNAK/T-2518-2017
dc.authorwosiddegim, ismail tuncer/AAG-4732-2019
dc.authorwosidDeğim, Zelihagül/GLV-6672-2022
dc.authorwosidDegim, Zelihagul/GLT-6743-2022
dc.contributor.authorOnurdag, Fatma Kaynak
dc.contributor.authorDegim, Tuncer
dc.contributor.authorDegim, Zelihagul
dc.contributor.authorKutlu, Ismail
dc.contributor.authorKaynar, Ozgur
dc.contributor.authorGunes, Gulsen
dc.contributor.authorAbbasoglu, Uflik
dc.date.accessioned2024-08-04T21:02:04Z
dc.date.available2024-08-04T21:02:04Z
dc.date.issued2008
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBrucellosis is an important zoonotic disease and the prevention is made by vaccination of animals. For ewes Brucella melitensis REV-I live attenuated vaccine is widely used but because of some risks such as being infected during the vaccination, re-infection of animals, a new vaccine with less side effect is need to be improved. In this Study it was aimed to determine a strong humoral immune response by encapsulating the Brucella outer membrane antigens with the optimum liposome formulation and the statistical analyses showed that the Brucella outer membrane extract encapsulated with liposome can evoke humoral immune response better than live attenuated B. melitensis REV-1 vaccine in mice.en_US
dc.description.sponsorshipGazi University Scientific Research Projectsen_US
dc.description.sponsorshipGazi University Scientific Research Projects (BAP) Unit provided the funding and the project was awarded in the XXXII Turkish Microbiology Congress. Animal experiments were done with the B.30.2. GUN.0. EU. 00.00/77-17292 numbered permission of Gazi University Animal Experiments Ethics Committee.en_US
dc.identifier.endpage995en_US
dc.identifier.issn1680-5593
dc.identifier.issn1993-601X
dc.identifier.issue8en_US
dc.identifier.startpage991en_US
dc.identifier.urihttps://hdl.handle.net/11616/104448
dc.identifier.volume7en_US
dc.identifier.wosWOS:000262561700020en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherMedwell Onlineen_US
dc.relation.ispartofJournal of Animal and Veterinary Advancesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBrucellaen_US
dc.subjectliposomesen_US
dc.subjecthumoral immunityen_US
dc.subjectvaccineen_US
dc.titleThe Humoral Immun Response of Mice to Liposomes Containing Brucella melitensis Outer Membrane Fragmentsen_US
dc.typeArticleen_US

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