HBsAg Screening in the Family Members of the Patients with Chronic Hepatitis B

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dc.authoridKayabas, Uner/0000-0002-5323-0796
dc.authoridBayindir, Yasar/0000-0003-3930-774X
dc.authorwosidKayabas, Uner/JRX-1616-2023
dc.authorwosidBayindir, Yasar/T-1523-2017
dc.contributor.authorKayabas, Uner
dc.contributor.authorBayindir, Yasar
dc.contributor.authorYologlu, Salim
dc.contributor.authorAkdogan, Dogan
dc.date.accessioned2024-08-04T20:58:54Z
dc.date.available2024-08-04T20:58:54Z
dc.date.issued2007
dc.departmentİnönü Üniversitesien_US
dc.description.abstractHepatitis B is one of the most common viral infections around the world. It is estimated that two billion people have been infected with hepatitis B virus and higher than 350 million have chronic hepatitis B. The aim of this study was to determine HBsAg positivity in the family members of index cases with chronic hepatitis B. Totally 375 subjects who were admitted to our outpatient clinic of Infectious Diseases between 2000 and 2003, were included in this study. Eighty-eight of them were index cases that were detected as HBsAg positive while 287 of them were the family members of the index cases. Thirty (34.1%) of the index cases were female and 58 (65.9%) were male. One hundred and fifty eight (55.1%) of the family members were female, 129 (44.9) were male. There were 36 HBsAg positive family members, 20 (55.5%) of them were male, 16 (44.5%) of them were female (p>0.05). The mean age of HBsAg positive family members and HBsAg negative family members were 26.5 +/- 14.7 (6-58) and 20.1 +/- 14.2 (range 1-60) (p=0.01), respectively. HBsAg positivity of fathers was higher than mothers (p=0.0003). HBsAg positivity was higher in off-springs of families that both parents have HBsAg positivity than families with mother-negative but father-positive HBsAg positivity (p<0.0001). In conclusion, intra-familial transmission is very important for HBV, therefore the family members of HBsAg positive index cases should be screened for HBsAg and if necessary they should be vaccinated.en_US
dc.identifier.endpage132en_US
dc.identifier.issn1307-9441
dc.identifier.issn2147-2939
dc.identifier.issue3en_US
dc.identifier.startpage128en_US
dc.identifier.urihttps://hdl.handle.net/11616/103283
dc.identifier.volume12en_US
dc.identifier.wosWOS:000217149200004en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isotren_US
dc.publisherGalenos Yayinciliken_US
dc.relation.ispartofViral Hepatit Dergisi-Viral Hepatitis Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectHepatitis B virusen_US
dc.subjectintra-familial transmissionen_US
dc.subjectindex caseen_US
dc.titleHBsAg Screening in the Family Members of the Patients with Chronic Hepatitis Ben_US
dc.typeArticleen_US

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