Evaluation of local and systemic side effects of Turkovac vaccine in adults

Basit Öğe Kaydı
dc.authoridKarahan, Doğu/0000-0002-5387-2000
dc.authorwosidKarahan, Doğu/HJI-2769-2023
dc.contributor.authorKalayci, Bulent Nuri
dc.contributor.authorKarahan, Dogu
dc.date.accessioned2024-08-04T20:58:44Z
dc.date.available2024-08-04T20:58:44Z
dc.date.issued2023
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground/aim: COVID-19 is a respiratory disease that caused a pandemic after reportedly emerging from Wuhan, China, in December 2019. Different types of COVID-19 vaccines such as viral vectors, mRNA, and inactivated vaccines have been produced since the beginning of the pandemic. Turkovac is an inactive COVID-19 vaccine developed and produced in Turkiye. We conducted our study to investigate the local and systemic side effects of the Turkovac vaccine. Materials and methods: A cross-sectional survey-based study was conducted to collect data on the postvaccine side effects in people aged over 18 who were vaccinated with Turkovac, between March and June 2022, in the Malatya Turgut Ozal University Research and Training Hospital. A 54 question, multiple-choice questionnaire was used to collect demographic data from the participants and identify the possible local and systemic side effects after Turkovac vaccine administration. Results: Of the 403 participants included in the study, 134 (33.3%) were female and 269 (66.7%) were male with a mean age of 47.7 +/- 13.7. The most common local side effects observed after vaccination were pain at the injection site (22.8%) and local swelling and redness (0.5%). Systemic side effects included weakness or fatigue (4.2%), muscle or joint pain (2%), headache (1.7%), fever (1%), cough (0.25%), lymphadenopathy (0.25%), and urticaria (0.25%). Side effects were most commonly observed within the first 24 h. We found that for participants under 47 years of age, female sex, chronic diseases, and regular medication use were associated with the risk of suffering side effects. Conclusion: Our study revealed that Turkovac is a generally well-tolerated vaccine and had no side effects. More studies are required to evaluate Turkovac's side effects in other populations.en_US
dc.identifier.doi10.55730/1300-0144.5657
dc.identifier.endpage940en_US
dc.identifier.issn1300-0144
dc.identifier.issn1303-6165
dc.identifier.issue4en_US
dc.identifier.pmid38031955en_US
dc.identifier.startpage934en_US
dc.identifier.urihttps://doi.org/10.55730/1300-0144.5657
dc.identifier.urihttps://hdl.handle.net/11616/103118
dc.identifier.volume53en_US
dc.identifier.wosWOS:001166710900010en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTubitak Scientific & Technological Research Council Turkeyen_US
dc.relation.ispartofTurkish Journal of Medical Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectSide effectsen_US
dc.subjectERU-CoVen_US
dc.subjectTurkovacen_US
dc.subjectvaccineen_US
dc.subjectCOVID-19en_US
dc.titleEvaluation of local and systemic side effects of Turkovac vaccine in adultsen_US
dc.typeArticleen_US

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