Stem cell mobilization kinetics in elderly patients with multiple myeloma
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Dosyalar
Tarih
2018
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Pergamon-elsevıer scıence ltd, the boulevard, langford lane, kıdlıngton, oxford ox5 1gb, england
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
In this study, we aimed to investigate whether the procedure and product kinetics differ according to age groups in advanced-age MM patients who underwent autologous HSCT. 59 patients who underwent autologous HSCT were retrospectively analyzed. Then, the patients were divided into two groups as 60-65 years and >= 65 years. It was significantly lower in >= 65 years group (p=0.008) and proportionally, the procedure duration was also significantly shortened in this group (p=0.013). Total number of collected CD34 positive stem cells was 6.20 x 106 (+/- 3.83) in 60-65 years group while it was 5.51 x 106 (+/- 2.48) in >= 65 years group with no statistically significant difference. (p=0.825). In conclusion, there was no significant difference in terms of the number of collected CD34-positive stem cells in this study that investigates the mobilization data, procedure and product kinetics, we think that successful stem cell mobilization can be performed in appropriately selected patients regardless of age. (C) 2018 Elsevier Ltd. All rights reserved.
Açıklama
Anahtar Kelimeler
Marrow transplantatıon, autologous transplantatıon, amerıcan socıety, g-csf, blood, collectıon, lymphoma, guıdelınes, therapy, age
Kaynak
Transfusıon and apheresıs scıence
WoS Q Değeri
Scopus Q Değeri
Cilt
57
Sayı
2
Künye
Dogu, MH . Batgi, H. Erkurt, MA. Hacioglu, S. (2018). Stem cell mobilization kinetics in elderly patients with multiple myeloma. Cilt:57. Sayı:2. 204-207 ss.
