Does cardiopulmonary bypass alter plasma level of tumor markers ca 125 and carcinoembryonic antigen

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dc.authorid9608en_US
dc.authorid8752en_US
dc.authorid223334en_US
dc.contributor.authorBattaloğlu, Bektaş
dc.contributor.authorErdil, Nevzat
dc.contributor.authorNisanoğlu, Vedat
dc.contributor.authorKoşar, Feridun
dc.contributor.authorÖzgür, Bülent
dc.contributor.authorYıldırım, Bülent
dc.contributor.authorKaragöz, Hüseyin
dc.date.accessioned2017-10-27T10:24:27Z
dc.date.available2017-10-27T10:24:27Z
dc.date.issued2002
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBACKGROUND: In addition to malignant diseases, acute and chronic inflammations may elevate plasma levels of tumor markers CA 125 and carcinoembryonic antigen (CEA). Cardiopulmonary bypass (CPB) causes a generalized inflammatory response. In this study, we have investigated the effect of CPB on plasma levels of CA 125 and CEA. METHODS: We measured plasma levels of CA 125 and CEA in patients undergoing coronary artery bypass grafting (CABG) with CPB (Group 1, n = 21), and in patients who underwent off-pump CABG, that is, without CPB (Group 2, n = 16). Blood samples were collected preoperatively, and on postoperative days 1, 6, and 12. RESULTS: Within both groups, CEA plasma levels were not significantly influenced in any samples. Comparing with preoperative values, CA 125 values elevated significantly on postoperative days 6 and 12 within both groups. It was observed that the elevation of CA 125 plasma levels in these samples were significantly higher in Group 1. CONCLUSIONS: The results indicate that CPB elevated plasma level of CA 125. However, clinical importance of this finding needed further evaluation.en_US
dc.identifier.citationBattaloglu B., Kaya E., Erdil N., Nisanoglu V., Kosar F., Ozgur B., Yıldırım B., Karagoz H.(2002). Does cardiopulmonary bypass alter plasma level of tumor markers ca 125 and carcinoembryonic antigen. Thorac Cardiovasc Surg. 2002 Aug;50(4):201-3.en_US
dc.identifier.doi10.1055/s-2002-33102en_US
dc.identifier.endpage203en_US
dc.identifier.issue0en_US
dc.identifier.startpage201en_US
dc.identifier.urihttps://www.thieme-connect.com/DOI/DOI?10.1055/s-2002-33102
dc.identifier.urihttps://hdl.handle.net/11616/7793
dc.identifier.volume50en_US
dc.language.isoenen_US
dc.publisherThe Thoracic and Cardiovascular Surgeonen_US
dc.relation.ispartofThe Thoracic and Cardiovascular Surgeonen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCardiopulmonary Bypassen_US
dc.subjectTumoren_US
dc.titleDoes cardiopulmonary bypass alter plasma level of tumor markers ca 125 and carcinoembryonic antigenen_US
dc.typeArticleen_US

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