Assessment of the relationship between clinical and histopathological features in cases of thyroidectomy

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dc.authoridAkbulut, Sami/0000-0002-6864-7711
dc.authoridyagmur, yusuf/0000-0002-1466-4583
dc.authorwosidAkbulut, Sami/L-9568-2014
dc.authorwosidyagmur, Yusuf/AHA-1738-2022
dc.authorwosidYagmur, Yusuf/E-2092-2015
dc.contributor.authorYagmur, Yusuf
dc.contributor.authorAkbulut, Sami
dc.contributor.authorSakarya, Hamdi
dc.contributor.authorSogutcu, Nilgun
dc.contributor.authorGumus, Serdar
dc.date.accessioned2024-08-04T20:57:12Z
dc.date.available2024-08-04T20:57:12Z
dc.date.issued2018
dc.departmentİnönü Üniversitesien_US
dc.description.abstractAim: The aim of this study is to evaluate the relationship between clinical parameters and ultimate histopathologic features of patients underwent thyroid surgery. METHOD: Demographic and clinicopathologic parameters of patients who underwent thyroid surgery for benign or malignant disease in our clinic between June 2006 and March 2014 were retrospectively reviewed. Pearson's Chi-Square, Independent Sample T test, ROC Curve and Youden J Index were used to investigate whether there was any relationship between the clinical parameters and permanent histopathologic features of patients. RESULTS: A total of 3059 patients (Benign: 2727; Malign: 332) aged between 15 and 90 years were reviewed. The patients age was higher in malign group (mean +/- SD: 468 +/- 4.2) than benign group (mean +/- SD: 43.7 +/- 12.9 yr) and this difference was statistically significant (p <0.001). The nodule diameter (mean +/- SD: 30.8 +/- 13.5 mm) was greater in malign group than the benign group (mean +/- SD: 28.3 +/- 13.4 mm) and this difference was statistically significant (p = 0.002). The sensitivity and specificity rates of the most appropriate cut-off point (> 26 mm) for the nodule size were 60% and 49.05%, respectively. Sensitivity, specificity, positive predictive value, negative predictive value and accuracy of FNAB were calculated as 4.17 %, 100 %, 100 %, 89.96% and 90 %, respectively. CONCLUSION: This study showed that higher age and greater nodule diameter (> 26 mm) are associated with malignancy.en_US
dc.identifier.endpage205en_US
dc.identifier.issn0003-469X
dc.identifier.issn2239-253X
dc.identifier.issue3en_US
dc.identifier.pmid30588916en_US
dc.identifier.startpage199en_US
dc.identifier.urihttps://hdl.handle.net/11616/102422
dc.identifier.volume89en_US
dc.identifier.wosWOS:000440878300002en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherEdizioni Luigi Pozzien_US
dc.relation.ispartofAnnali Italiani Di Chirurgiaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAgeen_US
dc.subjectLarge Nodule Diameteren_US
dc.subjectRisk factorsen_US
dc.subjectThyroid diseaseen_US
dc.subjectThyroid Canceren_US
dc.titleAssessment of the relationship between clinical and histopathological features in cases of thyroidectomyen_US
dc.typeArticleen_US

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