Impact of crush syndrome severity on clinical outcomes after the earthquakes in southeastern Turkiye

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dc.contributor.authorTurgutalp, Kenan
dc.contributor.authorOzturk, Savas
dc.contributor.authorKoc, Neriman Sila
dc.contributor.authorDolarslan, Murside Esra
dc.contributor.authorKocyigit, Ismail
dc.contributor.authorTurgut, Didem
dc.contributor.authorSahutoglu, Tuncay
dc.date.accessioned2026-04-04T13:33:09Z
dc.date.available2026-04-04T13:33:09Z
dc.date.issued2026
dc.departmentİnönü Üniversitesi
dc.description.abstractBackground: Crush syndrome is a potentially life-threatening complication of prolonged compression injuries, frequently encountered after earthquakes. The 2023 Kahramanmara & scedil; earthquakes in Turkiye caused extensive crush-related trauma. The objective of this study was to assess the effect of baseline crush syndrome severity on hospitalization outcomes and complications. Methods: In this multicenter, retrospective observational study, 962 crush syndrome patients hospitalized after the earthquakes were evaluated. Patients were grouped as mild-moderate vs. severe-critical based on clinical presentation. Demographics, laboratory results, comorbidities, trauma types, complications, and outcomes were assessed. Comparisons between groups were performed using the Mann-Whitney U test and chi-square test, and survival analysis was conducted with the Kaplan-Meier method. Results: Of 962 patients, 232 (24.1%) were classified as severe-critical and 730 (75.9%) as mild-moderate. Severe-critical patients had significantly higher rates of hypotension (38.8% vs 2.3%), ARDS (10.2% vs 1.7%), sepsis (31.7% vs 9.1%), DIC (8.5% vs 1.4%), arrhythmias (11.9% vs 0.8%), compartment syndrome (53.5% vs 36.9%), and ICU (95.6% vs 40.9%) requirement than mild-moderate (all p<0.001). Laboratory markers including BUN, creatinine, potassium, phosphorus, liver enzymes, CK, and CRP were all significantly elevated, while calcium and albumin levels were lower in the severe-critical group (p<0.05). Kaplan-Meier analysis revealed a significantly lower survival rate in the severe-critical group (67.7% vs. 97.7%, p<0.001). Trauma types such as cranial, abdominal, and thoracic injuries were more frequent in this group, and prolonged entrapment time [median 18 (8-40) vs. 10 (6-33) hours, p<0.05] was correlated with increased severity. Conclusions: Crush syndrome severity at admission is strongly correlated with clinical outcomes, complication rates, and in-hospital survival. Prolonged time under the rubble, systemic complications, and elevated muscle and renal injury markers contribute to worse prognosis. These findings highlight the need for rapid triage, timely fluid resuscitation, and organized multidisciplinary intervention in future disaster scenarios.
dc.identifier.doi10.1186/s12882-026-04757-9
dc.identifier.issn1471-2369
dc.identifier.issue1
dc.identifier.orcid0000-0002-2693-1167
dc.identifier.pmid41639834
dc.identifier.urihttps://doi.org/10.1186/s12882-026-04757-9
dc.identifier.urihttps://hdl.handle.net/11616/108971
dc.identifier.volume27
dc.identifier.wosWOS:001714340100001
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherBmc
dc.relation.ispartofBmc Nephrology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WOS_20250329
dc.subjectCrush syndrome
dc.subjectEarthquakes
dc.subjectAcute kidney injury
dc.subjectRhabdomyolysis
dc.subjectSoutheastern Turkiye
dc.titleImpact of crush syndrome severity on clinical outcomes after the earthquakes in southeastern Turkiye
dc.typeArticle

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