Assessment of left atrial volume and function by real time three-dimensional echocardiography inobese patients

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dc.contributor.authorYağmur, Julide
dc.contributor.authorCansel, Mehmet
dc.contributor.authorKurtoğlu, Ertuğrul
dc.contributor.authorHidayet, Siho
dc.contributor.authorAçıkgöz, Nusret
dc.contributor.authorErmis, Necip
dc.contributor.authorOzyalin, Fatma
dc.date.accessioned2019-07-30T07:41:31Z
dc.date.available2019-07-30T07:41:31Z
dc.date.issued2017
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjective: To evaluate left atrial (LA) volume and functions in obese subjects using real time three-dimensional echocardiography (RT3DE) and also the relationship between LA mechanical functions and N-terminal pro-atrial natriuretic peptide (NT-proANP). Methods: This study included 40 obese (26 females and 14 males, mean age 51.9 years) and 40 normal weight subjects (23 females and 16 males, mean age 53.5 years) with normal coronary angiograms. All the study participants underwent RT3DE to assess LA volume and mechanical function. Plasma NT-proANP was determined by ELISA method. Results: There was no significant difference between groups in left ventricular (LV) diameters and ejection fraction, which reflect LV systolic function. However, transmitral deceleration time, isovolumetric relaxation time, and peak late diastolic tissue Doppler velocity values, which reflect LV diastolic function, were found to be significantly higher in obese subjects when compared with controls. LA maximum volume (LAVmax), LAVmax index (LAVI), LA minimal volume (LAVmin), before atrial contraction volume (LAVpreA), LA active emptying volume, LA total emptying volume, and LA active emptying fraction, which reflect LA reservoir and pump functions, were also higher in obese subjects when compared with controls. LA passive emptying fraction was significantly lower in obese subjects than in controls. NT-proANP levels were similar between groups. There were positive correlations between NT-proANP level and LAVI, LAVmax, LAVmin, LAVpreA, and LA total and active emptying volumes. Conclusions: Left atrial mechanical functions and volumes are impaired in obese subjects. These findings may be regarded as early markers of subclinical cardiac failure in obese subjects who have not yet exhibited any clinical evidence of cardiovascular disease.en_US
dc.identifier.citationYagmur, J. Cansel, M. Kurtoglu, E. Hidayet, S. Acikgoz, N. Ermis, N. Ozyalin, F . (2017). Assessment of left atrial volume and function by real time three-dimensional echocardiography inobese patients.Cilt:34. Sayı:2. 210-216 ss.en_US
dc.identifier.doi10.1111/echo.13417en_US
dc.identifier.endpage216en_US
dc.identifier.issue2en_US
dc.identifier.startpage210en_US
dc.identifier.urihttps://hdl.handle.net/11616/13074
dc.identifier.volume34en_US
dc.language.isoenen_US
dc.publisherWıley, 111 rıver st, hoboken 07030-5774, nj usaen_US
dc.relation.ispartofEchocardıography-a journal of cardıovascular ultrasound and allıed technıquesen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBody-mass ındexen_US
dc.subjectrısken_US
dc.subjectfıbrıllatıonen_US
dc.subjecthearten_US
dc.subjectexpressıonen_US
dc.subjectpredıctoren_US
dc.subjectımpacten_US
dc.subjectsızeen_US
dc.titleAssessment of left atrial volume and function by real time three-dimensional echocardiography inobese patientsen_US
dc.typeArticleen_US

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