Futility versus acceptability of the use of grafts taken from end of line in the national organ sharing Network

dc.authorid110105en_US
dc.contributor.authorSoyer, Vural
dc.contributor.authorKoç, Süleyman
dc.contributor.authorOnur, Asım
dc.contributor.authorSarıcı, Kemal Barış
dc.contributor.authorKayaalp, Cüneyt
dc.contributor.authorIşık, Burak
dc.contributor.authorÜnal, Bülent
dc.contributor.authorYoloğlu, Saim
dc.contributor.authorYılmaz, Sezai
dc.date.accessioned2017-08-07T07:17:10Z
dc.date.available2017-08-07T07:17:10Z
dc.date.issued2015
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground. The number of suitable donors for organ transplantation is limited in many countries. This limitation can be overcome with the use of organs removed from marginal donors (expanded-criteria donors [ECDs]). We examined the long-term results of 187 patients who underwent marginal cadaveric liver transplantation in our institution. Methods. The data of patients who underwent cadaveric liver transplantation from January 2007 to April 2014 were retrospectively reviewed. ECDs were evaluated by considering 19 internationally accepted criteria. The clinical data of recipients including age, clinical status, and Model for End-Stage Liver Disease (MELD) score were also assessed. Results. A total of 287 patients underwent cadaveric liver transplantation. A graft from an ECD was used in 181 (63.06%) patients. The mean MELD score was 18.8. In all, 45 patients (24.86%) underwent transplantations for fulminant liver failure and 136 patients (75.14%) underwent transplantations for other chronic conditions. The majority of donors died of cerebrovascular disease and trauma. Only hypotension requiring inotropic drugs and obesity significantly affected survival. The 90-day and 12-month survival rates of the recipients who received a graft from an ECD were 51.93% and 46.2%, respectively. Conclusions. The use of ECD allografts immediately and significantly expands the existing donor pool. Because of persistent organ scarcity, pressure to use a greater proportion of the existing donor pool will continue to increase.en_US
dc.identifier.citationSoyer, V. Koç, S. Onur, A. Sarıcı, K. B. Kayaalp, C. Işık, B. Ünal, B. Yoloğlu, S. Yılmaz, S. (2015). Futility versus acceptability of the use of grafts taken from end of line in the national organ sharing Network. Transplantation Proceedings. 47(5), 1257–1261.en_US
dc.identifier.doi10.1016/j.transproceed.2015.04.067en_US
dc.identifier.issue5en_US
dc.identifier.startpage1257en_US
dc.identifier.urihttp://linkinghub.elsevier.com/retrieve/pii/S0041134515003929
dc.identifier.uri00411345
dc.identifier.urihttps://hdl.handle.net/11616/7466
dc.identifier.volume47en_US
dc.language.isoenen_US
dc.publisherTransplantation Proceedingsen_US
dc.relation.ispartofTransplantation Proceedingsen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleFutility versus acceptability of the use of grafts taken from end of line in the national organ sharing Networken_US
dc.typeArticleen_US

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