Uterine metastasis from infiltrating ductal carcinoma of breast in a patient receiving tamoxifen

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dc.contributor.authorMeydanli, MM
dc.contributor.authorKaradag, N
dc.contributor.authorAtaoglu, O
dc.contributor.authorKafkasli, A
dc.date.accessioned2024-08-04T21:02:23Z
dc.date.available2024-08-04T21:02:23Z
dc.date.issued2002
dc.departmentİnönü Üniversitesien_US
dc.description.abstractThe established relationship between tamoxifen and the development of endometrial cancer causes differential diagnostic problems between metastatic and primary uterine neoplasms. A 45-year-old woman underwent modified radical mastectomy because of left-breast cancer. She presented with abnormal vaginal bleeding 6 years later, while still on tamoxifen therapy. The endometrial curettage revealed undifferentiated adenocarcinoma. She underwent total abdominal hysterectomy, bilateral salphingoopherectomy as well as pelvic and periaortic lymphadenectomy. Microscopic examination revealed neoplastic cells which formed sheets and duct-like structures in the endometrium. The pattern was not that of a primary endometrial tumour and an immunohistochemical staining was performed using human breast gross cystic disease fluid protein-15 (GCDFP-15) which was found out to be positive in the tumour cells. A diagnosis of metastatic ductal carcinoma of the breast in the uterus was rendered. Uterine metastasis should be kept in mind in patients with a history of breast cancer who are on tamoxifen therapy. (C) 2002 Elsevier Science Ltd. All rights reserved.en_US
dc.identifier.doi10.1054/brst.2002.0447
dc.identifier.endpage356en_US
dc.identifier.issn0960-9776
dc.identifier.issn1532-3080
dc.identifier.issue4en_US
dc.identifier.pmid14965695en_US
dc.identifier.startpage353en_US
dc.identifier.urihttps://doi.org/10.1054/brst.2002.0447
dc.identifier.urihttps://hdl.handle.net/11616/104698
dc.identifier.volume11en_US
dc.identifier.wosWOS:000178709400014en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherChurchill Livingstoneen_US
dc.relation.ispartofBreasten_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCanceren_US
dc.subjectCorpusen_US
dc.titleUterine metastasis from infiltrating ductal carcinoma of breast in a patient receiving tamoxifenen_US
dc.typeArticleen_US

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