Is there any difference in risk factors between male and female patients in new-onset atrialfibrillation after coronary artery bypass grafting?

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dc.contributor.authorAkca, Baris
dc.contributor.authorErdil, Nevzat
dc.contributor.authorColak, Mehmet Cengiz
dc.contributor.authorDisli, Olcay Murat
dc.contributor.authorBattaloglu, Bektas
dc.contributor.authorColak, Cemil
dc.date.accessioned2019-07-16T07:40:35Z
dc.date.available2019-07-16T07:40:35Z
dc.date.issued2018
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground We aimed to investigate the risk factors of post-coronary artery bypass grafting (CABG) atrial fibrillation (AF) in male and female patients without any history of AF, to identify the sex-specific risk factors, and to examine the effect of sex-specific risk factors on the overall population. Methods This retrospective study was conducted using the hospital database with 4,758 patients who underwent CABG surgery. Among them, 2,836 patients with complete data participated in this study. The female patients were divided into two groups as patients who developed new-onset AF after CABG and those who did not. The relationship between the patients' variables and risk factors of post-CABG AF was examined. Results The overall incidence of post CABG AF was 12.9% (386/2,836). Sex-specific incidence of AF was similar: 3.2% (91/690) and 12.9% (277/2146) in female and male patients, respectively (p = 0.849). Multiple analysis revealed the independent risk factors for male and female patients, respectively: mean age (odds ratio [OR] = 1.057, OR = 1,076), age over 65 years (OR = 2.156, OR = 2.736), the European System For Cardiac Operative Risk Evaluation Scores (EuroSCORE) (OR = 1.13, OR = 1.218), COPD (OR = 1.589, OR = 1.789), BUN level (OR = 1.026, OR = 1.019), mean cardiopulmonary bypass (CPB) time (OR = 1.007, OR = 1.010), prolonged CPB time (OR = 1.604, OR = 2.309), mean cross-clamp time (OR = 1.009, OR = 1.017), need of inotropic support (OR = 2.249, OR = 2.731), and mean mechanical ventilation time (VT) (OR = 1.026, OR = 1.027). Low left ventricular ejection fraction (LVEF) (OR = 1.419), left ventricular (LV) aneurysm repair (OR = 1.533), carotid artery disease (OR = 1.750), prolonged VT (OR = 1.729), and use of intra-aortic balloon pump (IABP) (OR = 2.436) were found to be the risk factors only for male AF patients. Unstable angina (OR = 1.969), right coronary artery (RCA) disease (OR = 2), prolonged cross-clamp time (OR = 2.152), and the number of grafts per operation (OR = 1.298) were found to be the risk factors only for female AF patients. Conclusion This study suggests that predictors of AF in the overall population may be due to isolated patient groups. Multiple regression analysis and artificial intelligence modelling should be performed on large-scale, isolated groups to make strong AF prediction.en_US
dc.identifier.citationAkca, B. Erdil, N.Colak, MC. Disli, OM. Battaloglu, B.Colak, C. (2018). Is there any difference in risk factors between male and female patients in new-onset atrialfibrillation after coronary artery bypass grafting?.Cilt:66. Sayı:6. 483-490 ss.en_US
dc.identifier.doi10.1055/s-0038-1629921en_US
dc.identifier.endpage490en_US
dc.identifier.issue6en_US
dc.identifier.startpage483en_US
dc.identifier.urihttps://hdl.handle.net/11616/12618
dc.identifier.volume66en_US
dc.language.isoenen_US
dc.publisherGeorg thıeme verlag kg, rudıgerstr 14, d-70469 stuttgart, germanyen_US
dc.relation.ispartofThoracıc and cardıovascular surgeonen_US
dc.rightsinfo:eu-repo/semantics/restrictedAccessen_US
dc.subjectCardıac-surgeryen_US
dc.subjectelderly-patıentsen_US
dc.subjectpredıctorsen_US
dc.subjecttachyarrhythmıasen_US
dc.subjectmultıcenteren_US
dc.subjectarrhythmıasen_US
dc.subjectvarıablesen_US
dc.subjectımpacten_US
dc.titleIs there any difference in risk factors between male and female patients in new-onset atrialfibrillation after coronary artery bypass grafting?en_US
dc.typeArticleen_US

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