Prostatic and testicular parameters in lepromatous patients

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dc.authoridAglamis, Erdogan/0000-0002-7497-7573;
dc.authorwosidAglamis, Erdogan/AAA-7464-2020
dc.authorwosidceylan, cavit/JVZ-8616-2024
dc.contributor.authorAglamis, Erdogan
dc.contributor.authorTasdemir, Cemal
dc.contributor.authorYucel, Mehmet Ozgur
dc.contributor.authorCeylan, Cavit
dc.contributor.authorErden, Ilker
dc.date.accessioned2024-08-04T21:00:55Z
dc.date.available2024-08-04T21:00:55Z
dc.date.issued2014
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjectives: To evaluate PSA (Prostate-specific antigen) parameters in patients with lepromatous leprosy (LL). Design: In a retrospective study, 23 male patients with LL were evaluated. PSA parameters (serum total PSA (tPSA), free PSA (fPSA), free-to-total PSA ratio (f/tPSA), PSA Density (PSAD)) were assessed. PSA parameters were compared with a control group. Results: The mean tPSA, fPSA, f/tPSA, prostate volume, and PSAD values of the patient group with LL were 1.87 +/- 0.81 ng/ml, 0.67 +/- 0.29 ng/ml, 0.36 +/- 0.11, 41.08 +/- 23.65 ml and 0.055 +/- 0.037, respectively. The mean tPSA, fPSA, f/tPSA, prostate volume, and PSAD values of the control group were 2.71 +/- 0.91 ng/ml, 0.80 +/- 0.34 ng/ml, 0.30 +/- 0.08, 65.0 +/- 28.73 ml and 0.049 +/- 0.028, respectively. The mean tPSA and prostate volume values were found to be significantly lower in the patient group with LL (p = 0.002 and 0.004, respectively). No significant difference was found between two groups in terms of mean fPSA and PSAD values (p = 0.18 and 0.5, respectively). The mean f/tPSA value was found to be significantly higher in the patient group with LL (p = 0.02). Testes in 16(69%) patients with LL were bilaterally atrophic. Conclusions: Serum tPSA values and prostate volumes in the patients with LL were significantly reduced and f/tPSA values were significantly increased. Testicular atrophy in the lepromatous cases might be due to leprosy-related orchids and associated with a reduction in prostatic volume.en_US
dc.identifier.endpage53en_US
dc.identifier.issn0305-7518
dc.identifier.issn2162-8807
dc.identifier.issue1en_US
dc.identifier.pmid24974442en_US
dc.identifier.startpage48en_US
dc.identifier.urihttps://hdl.handle.net/11616/103933
dc.identifier.volume85en_US
dc.identifier.wosWOS:000337776100006en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherLepraen_US
dc.relation.ispartofLeprosy Reviewen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectTo-Total Psaen_US
dc.subjectHypogonadal Menen_US
dc.subjectIv Prostatitisen_US
dc.subjectCanceren_US
dc.subjectAntigenen_US
dc.subjectLeprosyen_US
dc.subjectTestosteroneen_US
dc.subjectDiagnosisen_US
dc.subjectSelectionen_US
dc.subjectDensityen_US
dc.titleProstatic and testicular parameters in lepromatous patientsen_US
dc.typeArticleen_US

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