Endothelial Dysfunction in Patients with Acromegaly

dc.authoridSahin, Ibrahim/0000-0002-6231-0034;
dc.authorwosidBentli, Recep/AAB-4140-2021
dc.authorwosidSahin, Ibrahim/ABI-6050-2020
dc.authorwosidKutlusoy, Ergun/ABB-9017-2020
dc.authorwosidŞahin, İbrahim/HHY-8303-2022
dc.contributor.authorSahin, Ibrahim
dc.contributor.authorBentli, Recep
dc.contributor.authorTopal, Ergun
dc.contributor.authorKeskin, Lezzan
dc.date.accessioned2024-08-04T20:58:39Z
dc.date.available2024-08-04T20:58:39Z
dc.date.issued2005
dc.departmentİnönü Üniversitesien_US
dc.description.abstractIt has been shown that Growth hormone (GH) and insulin like growth factor 1 (IGF-1) has important effects on heart and vascular system. However, little is known about endothelial function in acromegaly. The aim of this study was to determine endothelial function in patients with acromegaly. Endothelial function was evaluated in 10 patients with active acromegaly (eight men, two women) and in 11 age, sex and weight matched control (eight men, two women) using a flow mediated dilatation (FMD) technique in the brachial artery. In acromegalic patients mean FMD was 8.3 +/- 3.5 % and significantly lower than that of control group (p=.023). However, there were no significant correlations between GH, IGF-1 levels and percentage of FMD. These findings suggest that endothelial function impaired in patients with acromegaly.en_US
dc.identifier.endpage84en_US
dc.identifier.issn1301-2193
dc.identifier.issue3en_US
dc.identifier.startpage81en_US
dc.identifier.urihttps://hdl.handle.net/11616/103055
dc.identifier.volume9en_US
dc.identifier.wosWOS:000217273900002en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherGalenos Yayinciliken_US
dc.relation.ispartofTurkish Journal of Endocrinology and Metabolismen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAcromegalyen_US
dc.subjectEndothelial dysfunctionen_US
dc.subjectGrowth hormoneen_US
dc.titleEndothelial Dysfunction in Patients with Acromegalyen_US
dc.typeArticleen_US

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